An antimicrobial composition comprising at least two quaternary ammonium compounds selected from: (i) a quaternary ammonium compound having the formula: A.sub.4-nSi(R—NH.sub.aR.sup.1.sub.bZ)n and (ii) a quaternary ammonium compound having the formula: NHcR.sup.1dZ wherein in each of the at least two quaternary ammonium compounds A, R, R.sup.1, a, Z and n are independently selected, and: A is a member selected from the group consisting of alkoxy radicals, alkylether alkoxy radicals, and alkyl radicals; R is a divalent hydrocarbon radical; each R.sup.1 is independently a member selected from the group consisting of benzyl, alkyl radicals, alkyl ether hydrocarbon radicals, hydroxyl-containing alkyl radicals, and nitrogen-containing hydrocarbon radicals; Z is a member selected from the group consisting of chloride, bromide, iodide, tosylate, hydroxide, sulfate and phosphate; a is 0, 1 or 2, b is 1, 2 or 3, and the sum of a and b is 3; c is 0, 1, 2 or 3, d is 1, 2, 3 or 4, and the sum of c and d is 4; and n is 1, 2 or 3; and wherein the composition comprises at least two quaternary ammonium compounds of formula (i). A method of making an anti-microbial composition, and a method of reducing the number of micro-organisms on a surface, are disclosed.

An antimicrobial composition comprising at least two quaternary ammonium compounds selected from: (i) a quaternary ammonium compound having the formula: A.sub.4-nSi(R—NH.sub.aR.sup.1.sub.bZ)n and (ii) a quaternary ammonium compound having the formula: NHcR.sup.1dZ wherein in each of the at least two quaternary ammonium compounds A, R, R.sup.1, a, Z and n are independently selected, and: A is a member selected from the group consisting of alkoxy radicals, alkylether alkoxy radicals, and alkyl radicals; R is a divalent hydrocarbon radical; each R.sup.1 is independently a member selected from the group consisting of benzyl, alkyl radicals, alkyl ether hydrocarbon radicals, hydroxyl-containing alkyl radicals, and nitrogen-containing hydrocarbon radicals; Z is a member selected from the group consisting of chloride, bromide, iodide, tosylate, hydroxide, sulfate and phosphate; a is 0, 1 or 2, b is 1, 2 or 3, and the sum of a and b is 3; c is 0, 1, 2 or 3, d is 1, 2, 3 or 4, and the sum of c and d is 4; and n is 1, 2 or 3; and wherein the composition comprises at least two quaternary ammonium compounds of formula (i). A method of making an anti-microbial composition, and a method of reducing the number of micro-organisms on a surface, are disclosed.

An antimicrobial composition comprising at least two quaternary ammonium compounds selected from: (i) a quaternary ammonium compound having the formula: A.sub.4-nSi(R—NH.sub.aR.sup.1.sub.bZ)n and (ii) a quaternary ammonium compound having the formula: NHcR.sup.1dZ wherein in each of the at least two quaternary ammonium compounds A, R, R.sup.1, a, Z and n are independently selected, and: A is a member selected from the group consisting of alkoxy radicals, alkylether alkoxy radicals, and alkyl radicals; R is a divalent hydrocarbon radical; each R.sup.1 is independently a member selected from the group consisting of benzyl, alkyl radicals, alkyl ether hydrocarbon radicals, hydroxyl-containing alkyl radicals, and nitrogen-containing hydrocarbon radicals; Z is a member selected from the group consisting of chloride, bromide, iodide, tosylate, hydroxide, sulfate and phosphate; a is 0, 1 or 2, b is 1, 2 or 3, and the sum of a and b is 3; c is 0, 1, 2 or 3, d is 1, 2, 3 or 4, and the sum of c and d is 4; and n is 1, 2 or 3; and wherein the composition comprises at least two quaternary ammonium compounds of formula (i). A method of making an anti-microbial composition, and a method of reducing the number of micro-organisms on a surface, are disclosed.

[Problem to be Solved] An object of the present invention is to provide an aqueous antimicrobial composition which exhibits excellent antibacterial and antifungal activities even at a low concentration and has high safety, low skin irritation, and excellent long-term stability. [Solution] Aqueous antimicrobial compositions comprising two or more compounds selected from (a) benzoic acid or a salt thereof, (b) δ-gluconolactone, (c) ketonic acid or a salt thereof, and (d) sorbic acid or a salt thereof; and at least one or more dicarboxylic acid represented by General Formula (I) or a salt thereof.

[Problem to be Solved] An object of the present invention is to provide an aqueous antimicrobial composition which exhibits excellent antibacterial and antifungal activities even at a low concentration and has high safety, low skin irritation, and excellent long-term stability. [Solution] Aqueous antimicrobial compositions comprising two or more compounds selected from (a) benzoic acid or a salt thereof, (b) δ-gluconolactone, (c) ketonic acid or a salt thereof, and (d) sorbic acid or a salt thereof; and at least one or more dicarboxylic acid represented by General Formula (I) or a salt thereof.

The present invention relates to aqueous compositions of associative polyelectrolyte complexes (PECs), optionally containing surfactants, biocidal agents and/or oxidants, which can provide surface protection to treated articles including reduced soiling tendency, reduced cleaning effort and improved soil repellancy, as well as providing bacteriostatic properties to treated surfaces that thereby gain resistance to water, environmental exposure and microbial challenge. Treatment means and compositions are provided that employ associative polyelectrolyte complexes formed by combining a water soluble cationic first polyelectrolyte with a water soluble second polyelectrolyte bearing groups of opposite charge to the first polyelectrolyte under suitable mixing conditions where the one polyelectrolyte present in molar excess is added in the form of a first aqueous solution during a mixing step to a second aqueous solution comprising the oppositely charged polyelectrolyte present in molar deficiency. Also provided are means to form stable associative polyelectrolyte complexes in aqueous solutions having R values from about 0.10 to 20, including near stoichiometric R values approaching 1, being the ratio of charged groups present on the component polyelectrolytes employed.

The present invention relates to aqueous compositions of associative polyelectrolyte complexes (PECs), optionally containing surfactants, biocidal agents and/or oxidants, which can provide surface protection to treated articles including reduced soiling tendency, reduced cleaning effort and improved soil repellancy, as well as providing bacteriostatic properties to treated surfaces that thereby gain resistance to water, environmental exposure and microbial challenge. Treatment means and compositions are provided that employ associative polyelectrolyte complexes formed by combining a water soluble cationic first polyelectrolyte with a water soluble second polyelectrolyte bearing groups of opposite charge to the first polyelectrolyte under suitable mixing conditions where the one polyelectrolyte present in molar excess is added in the form of a first aqueous solution during a mixing step to a second aqueous solution comprising the oppositely charged polyelectrolyte present in molar deficiency. Also provided are means to form stable associative polyelectrolyte complexes in aqueous solutions having R values from about 0.10 to 20, including near stoichiometric R values approaching 1, being the ratio of charged groups present on the component polyelectrolytes employed.

The invention relates to an aqueous coating composition comprising a compound having reactive groups A, and a quaternary ammonium compound according to Formula I, II or III

##STR00001## wherein R.sup.1 is an alkyl, alkenyl, alkylaryl or arylalkyl group having from 5 to 50 carbon atoms; R.sup.2 is a C.sub.1-C.sub.100 hydrocarbyl group, optionally containing heteroatoms; R.sup.3 and R.sup.4 are alkylene groups having from 1 to 4 carbon atoms; R.sup.5 and R.sup.6 are H or C.sub.1-C.sub.100 hydrocarbyl group, optionally containing heteroatoms; R.sup.7 is a C.sub.1-C.sub.100 hydrocarbyl group, optionally containing heteroatoms; R.sup.8 is a C.sub.1-C.sub.100 hydrocarbyl group, optionally containing heteroatoms; R.sup.9 is H or a methyl group; Z is a substituent containing at least one reactive group B which is capable of reacting with the reactive group A; X.sup.− is an anion; y is 0 or 1; a is 0 or 1; and the sum of y and a is 1 or 2 and m is an integer from 1 to 30, preferably between 1 and 10, or between 2 and 6 n is an integer from 0-30, preferably between 1 and 10, or 2 and 6 T is a monomer unit; U is a monomer unit; V is a C.sub.1-C.sub.100 hydrocarbyl group, optionally containing hetero atoms; d is an integer between 1 and 5, preferably 1; e is an integer between 1 and 1000, preferably between 5 and 100; g is an integer between 1 and 100, preferably between 2 and 10; h is an integer between 1 and 5, preferably 2 or 3.

The invention relates to an aqueous coating composition comprising a compound having reactive groups A, and a quaternary ammonium compound according to Formula I, II or III

##STR00001## wherein R.sup.1 is an alkyl, alkenyl, alkylaryl or arylalkyl group having from 5 to 50 carbon atoms; R.sup.2 is a C.sub.1-C.sub.100 hydrocarbyl group, optionally containing heteroatoms; R.sup.3 and R.sup.4 are alkylene groups having from 1 to 4 carbon atoms; R.sup.5 and R.sup.6 are H or C.sub.1-C.sub.100 hydrocarbyl group, optionally containing heteroatoms; R.sup.7 is a C.sub.1-C.sub.100 hydrocarbyl group, optionally containing heteroatoms; R.sup.8 is a C.sub.1-C.sub.100 hydrocarbyl group, optionally containing heteroatoms; R.sup.9 is H or a methyl group; Z is a substituent containing at least one reactive group B which is capable of reacting with the reactive group A; X.sup.− is an anion; y is 0 or 1; a is 0 or 1; and the sum of y and a is 1 or 2 and m is an integer from 1 to 30, preferably between 1 and 10, or between 2 and 6 n is an integer from 0-30, preferably between 1 and 10, or 2 and 6 T is a monomer unit; U is a monomer unit; V is a C.sub.1-C.sub.100 hydrocarbyl group, optionally containing hetero atoms; d is an integer between 1 and 5, preferably 1; e is an integer between 1 and 1000, preferably between 5 and 100; g is an integer between 1 and 100, preferably between 2 and 10; h is an integer between 1 and 5, preferably 2 or 3.

Provided herein are photosensitizer compounds for use in a variety of clinical, industrial, and research applications. In particular, provided are deep eutectic solvents and natural deep eutectic solvents for use in killing of bacteria.