[Problem to be Solved] An object of the present invention is to provide an aqueous antimicrobial composition which exhibits excellent antibacterial and antifungal activities even at a low concentration and has high safety, low skin irritation, and excellent long-term stability. [Solution] Aqueous antimicrobial compositions comprising two or more compounds selected from (a) benzoic acid or a salt thereof, (b) δ-gluconolactone, (c) ketonic acid or a salt thereof, and (d) sorbic acid or a salt thereof; and at least one or more dicarboxylic acid represented by General Formula (I) or a salt thereof.

[Problem to be Solved] An object of the present invention is to provide an aqueous antimicrobial composition which exhibits excellent antibacterial and antifungal activities even at a low concentration and has high safety, low skin irritation, and excellent long-term stability. [Solution] Aqueous antimicrobial compositions comprising two or more compounds selected from (a) benzoic acid or a salt thereof, (b) δ-gluconolactone, (c) ketonic acid or a salt thereof, and (d) sorbic acid or a salt thereof; and at least one or more dicarboxylic acid represented by General Formula (I) or a salt thereof.

[Problem to be Solved] An object of the present invention is to provide an aqueous antimicrobial composition which exhibits excellent antibacterial and antifungal activities even at a low concentration and has high safety, low skin irritation, and excellent long-term stability. [Solution] Aqueous antimicrobial compositions comprising two or more compounds selected from (a) benzoic acid or a salt thereof, (b) δ-gluconolactone, (c) ketonic acid or a salt thereof, and (d) sorbic acid or a salt thereof; and at least one or more dicarboxylic acid represented by General Formula (I) or a salt thereof.

Compositions are provided that contain biologically active components of amniotic fluid including growth factors and other proteins, carbohydrates, lipids, and metabolites. The compositions containing biologically active components of amniotic fluid can be useful for a range of therapeutic treatments including joint and soft tissue repair, regulation of skin condition, and for use in organ preservation, such as for use in organ transplant procedures. Advantages of the compositions include that they can be reproducibly produced, without the inherent variability of amniotic fluid from individual donors, and that they are free of fetal waste.

Compositions are provided that contain biologically active components of amniotic fluid including growth factors and other proteins, carbohydrates, lipids, and metabolites. The compositions containing biologically active components of amniotic fluid can be useful for a range of therapeutic treatments including joint and soft tissue repair, regulation of skin condition, and for use in organ preservation, such as for use in organ transplant procedures. Advantages of the compositions include that they can be reproducibly produced, without the inherent variability of amniotic fluid from individual donors, and that they are free of fetal waste.

The present invention provides a method of controlling bacterial contamination using synergistic interactions of antimicrobials. The invention consists of combinations of chlorine dioxide and organic acid whose combined antimicrobial effect is greater than the sum of their individual activities, i.e., synergistic.

The present invention provides a method of controlling bacterial contamination using synergistic interactions of antimicrobials. The invention consists of combinations of chlorine dioxide and organic acid whose combined antimicrobial effect is greater than the sum of their individual activities, i.e., synergistic.

Solid low foaming and low pH all-purpose cleaning and disinfectant compositions are disclosed. The solid disinfectant compositions comprise approximately 50% w/w to approximately 75% w/w of citric acid encapsulated by a binder and approximately 1% to approximately 5.5% w/w of sodium benzoate. The solid cleaning and disinfectant compositions comprise approximately 50% w/w to approximately 75% w/w of citric acid encapsulated by a binder; approximately 1% to approximately 5.5% w/w of sodium benzoate; and approximately 10% w/w to approximately 15% w/w of sodium lauryl sulfate. The solid compositions are dissolved in water to produce a disinfectant solution comprising approximately 1.2% w/v to approximately 2% w/v citric acid and approximately 0.083% w/v to approximately 0.15% w/v sodium benzoate. A 10 minute contact time with the disinfectant solution provides a 5 log.sub.10 reduction in Staphylococcus aureus on a surface.

Solid low foaming and low pH all-purpose cleaning and disinfectant compositions are disclosed. The solid disinfectant compositions comprise approximately 50% w/w to approximately 75% w/w of citric acid encapsulated by a binder and approximately 1% to approximately 5.5% w/w of sodium benzoate. The solid cleaning and disinfectant compositions comprise approximately 50% w/w to approximately 75% w/w of citric acid encapsulated by a binder; approximately 1% to approximately 5.5% w/w of sodium benzoate; and approximately 10% w/w to approximately 15% w/w of sodium lauryl sulfate. The solid compositions are dissolved in water to produce a disinfectant solution comprising approximately 1.2% w/v to approximately 2% w/v citric acid and approximately 0.083% w/v to approximately 0.15% w/v sodium benzoate. A 10 minute contact time with the disinfectant solution provides a 5 log.sub.10 reduction in Staphylococcus aureus on a surface.

A topical sanitizing composition for reducing the concentration of non-enveloped viruses on the skin is provided. The topical sanitizing composition includes one or more pH adjusters, at least one carbomer, and at least about 50 wt. % of one or more C.sub.1-8 alcohols. The sanitizing composition with pH adjuster and carbomer is able to achieve at least a 3.0 log reduction in the concentration of the non-enveloped virus and in some cases passes the EN 14476 standard.