Compositions and methods for achieving hemostasis. Hemostatic compositions comprise a phospholipid, and optionally, an anti-infective agent. The hemostatic composition can be administered to a bleeding bone to achieve hemostasis.

Methods of using organophosphorus or organosulfur compounds to disperse, remove, or inhibit the growth of a biofilm, or inhibit the growth of, or kill a fungus or bacteria are provided.

Methods of using organophosphorus or organosulfur compounds to disperse, remove, or inhibit the growth of a biofilm, or inhibit the growth of, or kill a fungus or bacteria are provided.

Methods of using organophosphorus or organosulfur compounds to disperse, remove, inhibit the growth of a biofilm, or inhibit the growth of, or kill a fungus or bacteria provided.

Methods of using organophosphorus or organosulfur compounds to disperse, remove, inhibit the growth of a biofilm, or inhibit the growth of, or kill a fungus or bacteria provided.

The invention relates to the use of a wetting composition comprising (a) from 20 to less than 50 wt % of one or more C10 to C14 alcohol, (b) 25 to 70 wt % of a surfactant selected from a non-ionic, cationic, anionic and amphoteric surfactant, and (c) from 5 to 50 wt % of a polar component comprising at least one selected from (i) water, and (ii) up to 25 wt % of a water-miscible C1-C3 organic solvent in lowering the surface tension of non-aqueous liquids, to methods for using the wetting composition, and products and non-aqueous compositions containing the wetting composition.

The invention relates to the use of a wetting composition comprising (a) from 20 to less than 50 wt % of one or more C10 to C14 alcohol, (b) 25 to 70 wt % of a surfactant selected from a non-ionic, cationic, anionic and amphoteric surfactant, and (c) from 5 to 50 wt % of a polar component comprising at least one selected from (i) water, and (ii) up to 25 wt % of a water-miscible C1-C3 organic solvent in lowering the surface tension of non-aqueous liquids, to methods for using the wetting composition, and products and non-aqueous compositions containing the wetting composition.

The invention relates to the use of a wetting composition comprising a surfactant selected from a non-ionic, cationic, anionic and amphoteric surfactant in combination with from 10 to less than 50 wt % of at least one C10 to C14 alcohol and 10 to 30 wt % of a C4-C6 oxygen containing co-solvent in lowering the surface tension of non-aqueous liquids, to methods for using the wetting composition, and products including non-aqueous compositions containing the wetting composition.

The invention relates to the use of a wetting composition comprising a surfactant selected from a non-ionic, cationic, anionic and amphoteric surfactant in combination with from 10 to less than 50 wt % of at least one C10 to C14 alcohol and 10 to 30 wt % of a C4-C6 oxygen containing co-solvent in lowering the surface tension of non-aqueous liquids, to methods for using the wetting composition, and products including non-aqueous compositions containing the wetting composition.

Disclosed are compounds of Formula (I): ##STR00001##
or a salt thereof, wherein: X is CR.sub.4 or N; R.sub.1, R.sub.2, R.sub.3, R.sub.4, and A are defined herein. Also disclosed are methods of using such compounds as inhibitors of Bruton's tyrosine kinase (Btk), and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as autoimmune diseases and vascular disease.