Disclosed are genetically modified nudiviruses capable of being sexually transmitted by an insect useful for controlling pest populations. The genetically modified nudiviruses are capable of causing sterility in a target population of insects. Also disclosed are insects infected with the disclosed genetically modified nudiviruses, methods of making the genetically modified nudiviruses, and methods of using the genetically modified nudiviruses to control an insect pest population.

Disclosed are genetically modified nudiviruses capable of being sexually transmitted by an insect useful for controlling pest populations. The genetically modified nudiviruses are capable of causing sterility in a target population of insects. Also disclosed are insects infected with the disclosed genetically modified nudiviruses, methods of making the genetically modified nudiviruses, and methods of using the genetically modified nudiviruses to control an insect pest population.

A composition for use in formulations for controlling insect populations, including populations of mosquito and flies. The composition comprises one or more double-stranded constructs inhibitory to RNA transcription of ribosomal proteins. The invention also relates to method of using the compositions in formulations to inhibit insect populations.

Insecticidal toxins described herein are fused toxin peptides made up of a targeting domain fused to a toxin domain. The targeting peptide generates a specific association with mosquitoes by causing the fused toxin peptide to bind mosquitoes in a way that leads to the insecticidal activity. Transgenic plants described herein are mosquitocidal by expressing an insecticidal toxin protein in nectar that includes a targeting peptide to ensure specificity against mosquitoes. These transgenic plants serve as role models for safety, since they are non-crop plants and specific to one mosquito species.

Insecticidal toxins described herein are fused toxin peptides made up of a targeting domain fused to a toxin domain. The targeting peptide generates a specific association with mosquitoes by causing the fused toxin peptide to bind mosquitoes in a way that leads to the insecticidal activity. Transgenic plants described herein are mosquitocidal by expressing an insecticidal toxin protein in nectar that includes a targeting peptide to ensure specificity against mosquitoes. These transgenic plants serve as role models for safety, since they are non-crop plants and specific to one mosquito species.

A method for mosquito control is provided in the form of mosquito larvicide carrying insects which can be introduced in a mosquito population to thereby control the mosquito population. The larvicide carrier insects may include artificially generated adult insect carriers of a mosquito larvicide in which the mosquito larvicide has minimal impact on the adult insect carrier and which mosquito larvicide affects juvenile mosquito survival or interferes with metamorphosis of juvenile mosquitoes to adulthood. The larvicide carrier insects may be either male or female and may include mosquitoes and non-mosquito insects.

A method for mosquito control is provided in the form of mosquito larvicide carrying insects which can be introduced in a mosquito population to thereby control the mosquito population. The larvicide carrier insects may include artificially generated adult insect carriers of a mosquito larvicide in which the mosquito larvicide has minimal impact on the adult insect carrier and which mosquito larvicide affects juvenile mosquito survival or interferes with metamorphosis of juvenile mosquitoes to adulthood. The larvicide carrier insects may be either male or female and may include mosquitoes and non-mosquito insects.

A method of delivering an agricultural composition to a plant including determining a dose of the agricultural composition required to deliver a treatment effective amount of the at least one agrochemical agent to a target soil depth using a computational model, the agricultural composition including a plurality of plant viral nanoparticles (VNPs) and/or virus-like particles (VLPs) and at least one agrochemical agent, and applying the determined dose of the agricultural composition to the plant.

A method of delivering an agricultural composition to a plant including determining a dose of the agricultural composition required to deliver a treatment effective amount of the at least one agrochemical agent to a target soil depth using a computational model, the agricultural composition including a plurality of plant viral nanoparticles (VNPs) and/or virus-like particles (VLPs) and at least one agrochemical agent, and applying the determined dose of the agricultural composition to the plant.

A device and a method for clinically providing a preparation of autologous phages, namely, those that can verifiably be traced back to originating from a very specific person and preferably are also only intended for use in this one specific person includes a phage culturing device which is a fluid line system that is sealed off with respect to the outside environment The phages in the fluid line system obtained after at least one-time culturing are separated from bacteria by way of filtration, and preferably by way of tangential flow filtration. The phages separated by way of filtration are transferred into a collection vessel that is connected to the fluid line system and are preferably removed from the fluid line system, using the collection vessel, as a usable, preferably autologous preparation.