The present invention is a system and method for performing freeze drying of small quantities of a liquid for personal use, wherein a liquid material is disposed within a single-use container, the container is then coupled to a small-scale freeze-drying unit which extracts liquid from the material in the container using a freeze-drying process, and the freeze-dried material is then left in the container and the container is stored until rehydration. The container may be a specialized single-use container that may be used to rehydrate the liquid and then fitted with a delivery device to feed an infant or child.

The present invention is a system and method for performing freeze drying of small quantities of a liquid for personal use, wherein a liquid material is disposed within a single-use container, the container is then coupled to a small-scale freeze-drying unit which extracts liquid from the material in the container using a freeze-drying process, and the freeze-dried material is then left in the container and the container is stored until rehydration. The container may be a specialized single-use container that may be used to rehydrate the liquid and then fitted with a delivery device to feed an infant or child.

A novel method for freeze-related separations, involving the combination of water with a selected concentration of biogenic ice nucleation proteins, freezing the combination, and separating the ice, potentially via centrifugation or sublimation. In some instances, the freezing conditions and the concentration of the at least one biogenic ice nucleation protein are selected such that the aqueous solution, upon freezing, forms a lamellar ice crystal structure having at least one property selected from the group consisting of a solute inclusion volume at least 30% smaller than in the first material alone, a hydraulic diameter at least 30% larger than in the first material alone, an inclusion width that is less than 10% of a crystal dimension, a hydraulic diameter that is less more than 1.5 times that of an inclusion width, a deviation of crystal orientation angle in the transverse direction of less than 45 degrees, an ice crystal length in the transverse direction that is at least 10% larger than in the first material alone, and a length of the ice crystal structure in the longitudinal direction that is at least 10% larger than in the first material alone. The use of these structures result in a significant efficiency improvement and energy savings.

A novel method for freeze-related separations, involving the combination of water with a selected concentration of biogenic ice nucleation proteins, freezing the combination, and separating the ice, potentially via centrifugation or sublimation. In some instances, the freezing conditions and the concentration of the at least one biogenic ice nucleation protein are selected such that the aqueous solution, upon freezing, forms a lamellar ice crystal structure having at least one property selected from the group consisting of a solute inclusion volume at least 30% smaller than in the first material alone, a hydraulic diameter at least 30% larger than in the first material alone, an inclusion width that is less than 10% of a crystal dimension, a hydraulic diameter that is less more than 1.5 times that of an inclusion width, a deviation of crystal orientation angle in the transverse direction of less than 45 degrees, an ice crystal length in the transverse direction that is at least 10% larger than in the first material alone, and a length of the ice crystal structure in the longitudinal direction that is at least 10% larger than in the first material alone. The use of these structures result in a significant efficiency improvement and energy savings.

The present invention is a system and method for performing freeze drying of small quantities of a liquid for personal use, wherein a liquid material is disposed within a single-use container, the container is then coupled to a small-scale freeze-drying unit which extracts liquid from the material in the container using a freeze-drying process, and the freeze-dried material is then left in the container and the container is stored until rehydration. The container may be a specialized single-use container that may be used to rehydrate the liquid and then fitted with a delivery device to feed an infant or child.

The present invention is a system and method for performing freeze drying of small quantities of a liquid for personal use, wherein a liquid material is disposed within a single-use container, the container is then coupled to a small-scale freeze-drying unit which extracts liquid from the material in the container using a freeze-drying process, and the freeze-dried material is then left in the container and the container is stored until rehydration. The container may be a specialized single-use container that may be used to rehydrate the liquid and then fitted with a delivery device to feed an infant or child.

The present invention provides novel oral dosage comprising lyophilized mammalian (human) milk and optionally a physiologically acceptable excipient or carrier, and their use for improvement of mammalian (human) health. Also provided a novel process for preparing lyophilized mammalian milk with desired nutritional and cellular content, initially freezing raw milk obtained from a mammalian source, forming a layer of a predefined thickness from the frozen milk at a temperature from −4° C. to −80° C., and drying the formed layer at a temperature from −20° C. to +60° C. at a pressure from 5 micron Hg to atmospheric pressure to provide the lyophilized human milk. The process optionally comprises comprising treating said lyophilized milk via flash supercritical CO.sub.2 treatment comprising soaking said lyophilized milk with supercritical CO.sub.2

The present invention provides novel oral dosage comprising lyophilized mammalian (human) milk and optionally a physiologically acceptable excipient or carrier, and their use for improvement of mammalian (human) health. Also provided a novel process for preparing lyophilized mammalian milk with desired nutritional and cellular content, initially freezing raw milk obtained from a mammalian source, forming a layer of a predefined thickness from the frozen milk at a temperature from −4° C. to −80° C., and drying the formed layer at a temperature from −20° C. to +60° C. at a pressure from 5 micron Hg to atmospheric pressure to provide the lyophilized human milk. The process optionally comprises comprising treating said lyophilized milk via flash supercritical CO.sub.2 treatment comprising soaking said lyophilized milk with supercritical CO.sub.2

The present invention relates to a process for preparing a freeze-dried composition selected from infant formula, follow-on formula or growing up milk, said composition comprises large lipid globules, preferably coated with polar lipids.

The present invention relates to a process for preparing a freeze-dried composition selected from infant formula, follow-on formula or growing up milk, said composition comprises large lipid globules, preferably coated with polar lipids.