The present invention relates to a prolonged release formulation of caffeine, which comprises of caffeine embedded in a continuous phase of non-polymeric release controlling carrier. The formulation may be optionally comprised of one or more excipients which are acceptable in nutraceutical and food industry. The invention also relates to a process for preparation; wherein caffeine is uniformly distributed throughout the continuous phase of non-polymeric release controlling carrier to get single-phase granules. The formulation releases caffeine through continuous phase of non-polymeric release controlling carrier, wherein about 20 to 60% of caffeine is released in first hour, followed by about 50-90% of release in 4-8 hours and about 70 to 100% of caffeine release in 8-12 hours. Caffeine formulation can advantageously be administered to a subject for achieving stimulant effect through prolonged release of caffeine over entire day.

A liquid egg analog has a composition comprising water, lupin protein, pea protein, oil, high acyl and low acyl gellan gum, tetrasodium pyrophosphate, isomaltooligosaccharide, acidulant, and divalent cations of magnesium and calcium. A method of preparing the liquid egg analog combines water, lupin protein and pea protein to produce a protein mix, combines water and gellan gums to produce a gel mix, and combines the protein mix and gel mix with the remaining ingredients to produce a combined mixture. The combined mixture may then be pasteurized, cooled and bottled.

Complex containing betaine, transition metal and sulfate in a ratio of 1:1:1, the transition metal being coordinated with two oxygen atoms from the betaine.

Food distributed to consumers through a distribution chain may be traced by tagging the food with DNA tags that identify the origin of the food, such as the grower, packer and other points of distribution, and their attributes. This makes it much quicker and easier to trace the food in case of food contamination or adulteration. Preferably these attributes indicate the field, location, crew and machine used to grow and process the food, and the dates of the various steps of food harvesting, processing and distribution. Natural or synthetic DNA pieces may be used to tag items, including food items. Multidigit binary or other types of bar codes may be represented by multiple types of DNA. Each digit of the bar code may be represented by one, two or more unique DNA pieces.

Disclosed are TRPM8 modulators as defined by formula (I) for achieving a cooling effect on skin and mucosa.

The present invention relates to a pharmaceutical composition for preventing or treating hair loss, a health functional food composition or a cosmetic composition, including a specific compound or a pharmaceutically acceptable salt thereof as an active ingredient, wherein the compound exhibits an excellent hair growth recovery effect in hair follicle tissues in which hair growth is inhibited without cytotoxicity, and thus hair loss can be more effectively prevented, improved, or treated.

A formulation for providing hydration and nutritional components to a subject includes from about 1,000 mg/serving to about 7,000 mg/serving of trimethylglycine, a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable precursor thereof; from about 1 mg/serving to about 4,000 mg/serving of beta-hydroxybutyric acid or a pharmaceutically acceptable salt thereof; an electrolyte salt; optionally a purine nucleotide; and optionally a carbohydrate. The formulation may be an orally administered liquid including an aqueous carrier in an amount sufficient to provide a total volume/serving of about 2 oz. to about 32 oz.

The present disclosure is directed to compositions of caffeine citrate. In addition, the present disclosure includes processes of making compositions of caffeine citrate and methods of treatment using caffeine citrate. Such methods include methods of accelerating emergence from anesthesia by delivering compositions of caffeine citrate of the disclosure.

Supplemental food formulations are described herein that can contain various nutrients, including at least four of the following: amino acid blend, fulvic-humic acids, multi-minerals, glycerin, phosphatidylinositol, sesquiterpene alkaloids, terpenes, medium-chain triglycerides (MCTs), coconut oil, whole plant matter, plant seeds, mushrooms, seaweeds, kelp, and flavoring agents.

The present invention relates to a pharmaceutical composition, a food composition, and a food additive for the prevention and treatment or improvement of muscle loss, muscle weakness, and muscle atrophy, which contain Enterococcus faecalis, particularly Enterococcus faecalis EF-2001 among others, a culture solution thereof, or a killed body thereof as an active ingredient. Killed Enterococcus faecalis EF-2001 of the present invention exhibits a remarkable treatment effect for muscle loss, muscle weakness, and muscle atrophy by inhibiting the damage to muscle cells induced by oxidative stress, and thus killed lactic acid bacterium Enterococcus faecalis EF-2001 of the present invention or a culture solution thereof can be usefully used as an active ingredient in a pharmaceutical composition, a food composition, and a food additive for prevention of muscle atrophy and sarcopenia.