Methods of decreasing muscle atrophy and/or promoting muscle regeneration in a subject at risk of muscle atrophy comprise orally administering a nutritional composition comprising at least one of protein, fat and carbohydrate, and bovine milk-isolated exosomes comprising intact exosomes. In specific embodiments, the subject suffers from malnutrition, acquired immune deficiency syndrome (AIDS), cancer, diabetes, chronic obstructive pulmonary disease (COPD), amyotrophic lateral sclerosis (ALS), non-alcoholic fatty liver disease (NAFLD), or a burn injury, or has undergone clinical corticosteroid treatment.

The present application relates to the administration of plasma, fractions thereof, or mixtures thereof to humans or animals to treat or otherwise improve cognitive impairment disorders, including dementia (e.g., vascular dementia, dementia with Lewy bodies, dementia resulting from Alzheimer's disease, dementia resulting from Parkinson's disease, frontotemporal dementia, and dementia resulting from normal pressure hydrocephalus in humans, and cognitive dysfunction syndrome in companion animals), concussion, and traumatic brain injury. In certain embodiments, the invention comprises a method of treating a cognitive impairment disorder in a human or companion animal subject, said method comprising: administering to said subject one or more cognitive functioning tests to identify a subject suffering from a cognitive impairment disorder; and administering to said subject a therapeutically effective amount of an animal plasma composition; wherein said administration provides an improvement in said subject's results in said one or more cognitive impairment tests.

The present application relates to the administration of plasma, fractions thereof, or mixtures thereof to humans or animals to treat or otherwise improve cognitive impairment disorders, including dementia (e.g., vascular dementia, dementia with Lewy bodies, dementia resulting from Alzheimer's disease, dementia resulting from Parkinson's disease, frontotemporal dementia, and dementia resulting from normal pressure hydrocephalus in humans, and cognitive dysfunction syndrome in companion animals), concussion, and traumatic brain injury. In certain embodiments, the invention comprises a method of treating a cognitive impairment disorder in a human or companion animal subject, said method comprising: administering to said subject one or more cognitive functioning tests to identify a subject suffering from a cognitive impairment disorder; and administering to said subject a therapeutically effective amount of an animal plasma composition; wherein said administration provides an improvement in said subject's results in said one or more cognitive impairment tests.

The present invention relates to a composition comprising amniotic epithelial cell-derived exosomes as an active ingredient for prevention or treatment of ocular diseases and, more specifically, to a pharmaceutical composition for prevention or treatment of ocular diseases and a health functional food composition for prevention or alleviation of ocular diseases, each composition comprising amniotic epithelial cell-derived exosomes as an active ingredient. The amniotic epithelial cell-derived exosomes have ability to heal wounds on ocular tissues, recover the lacrimal gland destroyed by ocular diseases to induce lacrimation, and reduce the secretion of various inflammatory cytokines, thereby further effectively preventing or treating ocular diseases.

An antibiotic composition containing a wasp extract as an active ingredient, and more particularly, a pharmaceutical composition and a health functional food for preventing, ameliorating or treating diabetes by α-amylase inhibition and α-glucosidase inhibition, which contain a wasp extract as an active ingredient. The wasp extract exhibits strong antidiabetic activity by effectively inhibiting amylase, has no human erythrocyte hemolytic activity, has excellent heat stability, and the activity thereof is not lost even under an acidic condition of pH 2 and in plasma. The wasp extract of the present disclosure may be processed into various forms such as extracts, powders, pills or tablets, which can be taken at all times.

An antibiotic composition containing a wasp extract as an active ingredient, and more particularly, a pharmaceutical composition and a health functional food for preventing, ameliorating or treating diabetes by α-amylase inhibition and α-glucosidase inhibition, which contain a wasp extract as an active ingredient. The wasp extract exhibits strong antidiabetic activity by effectively inhibiting amylase, has no human erythrocyte hemolytic activity, has excellent heat stability, and the activity thereof is not lost even under an acidic condition of pH 2 and in plasma. The wasp extract of the present disclosure may be processed into various forms such as extracts, powders, pills or tablets, which can be taken at all times.

The invention relates to a method for the provision of degutted insects, such as black soldier fly larvae and mealworm, preferably live degutted insects. The invention also relates to degutted (live or dead) insects such as larvae and to processed degutted insects such as larvae. The invention also relates to the use of the degutted insect according to the invention or use of the processed degutted insect of the invention for the separation of the degutted insect or of the processed degutted insect in at least a fat fraction and/or at least a protein fraction. In addition, the invention relates to an insect product, wherein the insect product is any one of live or dead insect, insect puree, minced insect, insect powder, particulate insect, granulated insect, or insect meal, dried insect, oven-dried insect, lyophilized insect, or oven-dried insect using refractive drying obtained from degutted insect provided with the method of the invention. The invention also relates to an insect product, wherein the insect product is insect gut content, wherein the gut content is provided with the method of the invention. Finally, the invention relates to the method, the degutted insect provided with the method, the degutted insect, insects products, insect gut content according to the invention, wherein the insect is black soldier fly, preferably black soldier fly larvae, or wherein the insect is mealworm.

The present invention relates to a composition comprising Cricket or an extract thereof for improving a bowel movement function or weight loss.

The invention is a nutritional composition in unit dosage form for oral administration to an animal or human, which includes at least one ingredient from each of six biological Kingdoms selected from the group consisting of animals, plants, fungi, bacteria, protist and archaea. Each ingredient is co-admixed with every other said ingredient without further addition of synthetic excipients or fillers, and is typically formulated in dried powder form as a drink mix, food or beverage additive or as the fill for hard or soft capsules or other dosage forms including tablets (the compositions of the invention can generally be tableted without addition of ingredients beyond the nutrients themselves).

The invention is a nutritional composition in unit dosage form for oral administration to an animal or human, which includes at least one ingredient from each of six biological Kingdoms selected from the group consisting of animals, plants, fungi, bacteria, protist and archaea. Each ingredient is co-admixed with every other said ingredient without further addition of synthetic excipients or fillers, and is typically formulated in dried powder form as a drink mix, food or beverage additive or as the fill for hard or soft capsules or other dosage forms including tablets (the compositions of the invention can generally be tableted without addition of ingredients beyond the nutrients themselves).