A hollow probe enabling insertion and accommodation of endoscopic and other instruments advancing within a lumen includes a central valve unit featuring a central bore and at least one valve for controlling the introduction and withdrawal of fluid into the central bore. A sliding tubular sheath is movably disposed inside the central valve unit. An impermeable flexible sleeve is sealingly anchored to the central valve unit and folds over to cover both the inside and outside of the sheath to sealingly envelop the sheath and contain the fluid, together with the valve unit, while allowing sliding of the sleeve-covered-sheath. An endoscope adapter is mountable to the proximal end of the sleeve-covered-sheath, for allowing insertion of the endoscope through the adapter into the sleeve-covered-sheath, includes at least one gasket for sealing at least one gap between the endoscope and the sleeve-covered-sheath for withholding fluids from escaping.

Described embodiments include a capsule, including a cyclically everting sleeve shaped to define a sleeve interior, a fluid, configured to facilitate the everting of the sleeve, contained within the sleeve interior, and a plurality of electrically-conductive coils coupled to the sleeve. The coils are configured to, when at least two of the coils are magnetized, advance the capsule within a lumen by applying an everting force to the sleeve. Other embodiments are also described.

Devices and methods of use for an endoscopic accessory device that can be assembled and advanced over an endoscope positioned at a site within the body, the endoscopic accessory device including a body structure having seam structures on opposite sides of an elongate body structure, where the seam structures can be releasably joined to transform the body structure from a planar configuration to a tubular configuration.

The present disclosure provides an introducer device including an outer tube defining a first lumen, and an inner tube defining a second lumen, and a sheath coupled thereto. The first end of the inner tube is positioned in the first lumen of the outer tube, and the inner tube is configured to translate within the first lumen in a direction towards the first end of the outer tube from a first position to a second position. The first end of the sheath is coupled to the first end of the outer tube, and the second end of the sheath is coupled to the first end of the inner tube. The introducer device further includes an inlet port in fluid communication with the inner surface of the outer tube, and one or more steering wires coupled to the sheath that are configured to bias a direction of a leading edge of the sheath as the sheath everts from a retracted position to an extended position.

Biological navigation devices and methods are disclosed. The devices can be used as or to support colonoscopies or endoscopes. The devices can have longitudinally extensible cells that can be selectively inflated. The devices can have articulable links. The devices can be removably attached to elongated elements, such as colonoscopes or other endoscopes.

This invention relates to a robot to improve the inspection of a pipe or lumen. More particularly, this invention relates to a soft-pneumatic robot for endoscopy that is suitable for performing colonoscopy procedures. The robot of this invention comprises leading and tailing balloons configured for selective inflation to anchor a portion of the robot within the pipe or lumen and a soft-pneumatic actuator that is located between the leading balloon and the trailing balloon. The soft-pneumatic actuator is operable to extend or contract the robot in a longitudinal direction, in addition to positioning the leading balloon in a 360 degree circumference around the longitudinal direction by pneumatically controlling a fluid within a plurality of chambers within the soft-pneumatic actuator.

The present disclosure describes a rolling sleeve having a malleable body. The rolling sleeve is configured to protect an endoluminal shaft from surrounding tissue during insertion, navigation, and/or treatment within a body lumen.

An endoscopic probe which advances within a lumen having a central valve unit. The valve unit has a central bore defining a proximal end and a distal end, and at least one valve for controlling the introduction and withdrawal of fluid into the central bore. The probe further includes a sliding tubular sheath movably disposed inside the central valve unit, and a flexible sleeve, impermeable to the fluid and sealingly anchored to the central valve unit on both distal proximal ends. The sleeve is folded over to cover both the inside and outside of the sheath to sealingly envelop the sheath and contain the fluid, together with said valve unit, while allowing sliding of the sheath. A method for providing, assembling and operating the probe is also provided.

Provided is a system for advancing an article along a path. The system may include a head member, a dispatching member, and an eversion sleeve. Also provided is a method for assembling a system for advancing an article along a path.

Endolumenal devices and methods can be used for the treatment of health conditions including obesity and diabetes. In some embodiments, the methods and systems provided herein can cause weight loss or control diabetes by reducing the caloric absorption of an individual. For example, this document provides several devices and methods for treating obesity and diabetes by using electroporation to modulate the duodenal mucosa. In addition, this document provides devices and methods for bypassing portions of the gastrointestinal tract to reduce nutritional uptake.