To generate a medical image with high visibility in fluorescence observation. A medical image generation apparatus (100) according to the present application includes an acquisition unit (131), a calculation unit (132), and a generation unit (134). An acquisition unit (131) acquires a first medical image captured with fluorescence of a predetermined wavelength and a second medical image captured with fluorescence of a wavelength different from the predetermined wavelength. A calculation unit (132) calculates a degree of scattering, indicating a degree of blurring of fluorescence of a living body, included in the first medical image and the second medical image acquired by the acquisition unit (131). A generation unit (134) generates an output image on the basis of at least one of the degrees of scattering calculated by the calculation unit (132).

A medical image processing apparatus includes an image processor configured to: receive a plurality of first image data captured at different times and generated by illumination of light in a first wavelength band in sequence; receive a plurality of second image data captured at different times and generated by illumination of light in a second wavelength band different from the first wavelength band in sequence; generate first and second images based on the received first and second image data, respectively; and output the generated first image and second image to a display in chronological order of the first and second images and in accordance with a preset display pattern of the first and second images.

A medical imaging system is described that comprises an heating element configured to apply at least one heating pattern element to a material to locally heat the material; a sensor configured to capture the position of the heated material a predetermined time after the application of the heating pattern element; and circuitry configured to determine the change of the heating pattern applied to the material based upon the captured position of the heated material after the predetermined time.

The present disclosure relates to compounds that are useful as near-infrared fluorescence probes, wherein the compounds include i) a ligand that binds to the active site of carbonic anhydrase, ii) a dye molecule, and iii) a linker molecule that comprises an amino acid, amide, ureido, or polyethylene glycol derivative thereof. The disclosure further describes methods and compositions for making and using the compounds, methods incorporating the compounds, and kits incorporating the compounds.

Fluorescence imaging with reduced fixed pattern noise is disclosed. A method includes actuating an emitter to emit a plurality of pulses of electromagnetic radiation and sensing reflected electromagnetic radiation resulting from the plurality of pulses of electromagnetic radiation with a pixel array of an image sensor to generate a plurality of exposure frames. The method includes applying edge enhancement to edges within an exposure frame of the plurality of exposure frames. The method is such that at least a portion of the plurality of pulses of electromagnetic radiation emitted by the emitter comprises one or more of electromagnetic radiation having a wavelength from about 770 nm to about 790 nm.

A neurosurgical ultrasonic focusing assisted three-stage atomization cooling and postoperative wound film forming device has a transducer housing and a nozzle, wherein a horn is arranged in the transducer housing, at least two layers of piezoelectric ceramic sheets are arranged at the top of the horn, an electrode sheet connected with an ultrasonic generator is arranged between two adjacent layers of piezoelectric ceramic sheets, the bottom of the transducer housing is of a hemispherical structure, and a plurality of piezoelectric elements connected with the ultrasonic generator are arranged inside the hemispherical structure; and the nozzle is arranged at the bottom of the horn and connected with a medical nanofluid storage cup, compressed gas can also be introduced into the nozzle, and an electrode is also arranged inside the nozzle.

A visualization system including multiple light sources, an image sensor configured to detect imaging data from the multiple light sources, and a control circuit is disclosed. At least one of the light sources is configured to emit a pattern of structured light. The control circuit is configured to receive the imaging data from the image sensor, generate a three-dimensional digital representation of the anatomical structure from the pattern of structured light detected by the imaging data, obtain metadata from the imaging data, overlay the metadata on the three-dimensional digital representation, receive updated imaging data from the image sensor, and generate an updated three-dimensional digital representation of the anatomical structure based on the updated imaging data. The visualization system can be communicatively coupled to a situational awareness module configured to determine a surgical scenario based on input signals from multiple surgical devices.

An endoscope with an optical channel is held and positioned by a robotic surgical system. A capture unit captures (1) a visible first image at a first time and (2) a visible second image combined with a fluorescence image at a second time. An image processing system receives (1) the visible first image and (2) the visible second image combined with the fluorescence image and generates at least one fluorescence image. A display system outputs an output image including an artificial fluorescence image.

An endoscope device includes: an normal light image acquisition unit that acquires an normal light image; a special light image acquisition unit that acquires a special light image; a blended image generation unit that generates a blend image by combining one color component image from among a plurality of color component images constituting the normal light image and the special light image; and a superimposed image generation unit that generates a color superimposed image by combining the blended image with another color component image. The blended image generation unit generates the blended image by replacing a part of the pixels of the one color component image with the corresponding pixels of the special light image such that they are blended in a substantially uniform distribution over the entire blended image.

An endoscope system includes an image pickup section that picks up, light included in return light generated according to radiation of excitation light, and reference light, the return light including the fluorescence, light in a first wavelength band, and light in a second wavelength band; an observation image generation section that generates an observation image using first through third image signals obtained by picking up the return light; and a control section that controls the observation image generation section such that the observation image is generated, by causing the first image signal to be assigned to a green component, and by causing one image signal having a relatively large signal value, between the second image signal and the third image signal, to be assigned to a red component and another image signal having a relatively small signal value to be assigned to a blue component and the green component.