An ultrasound device (10) comprises a probe (12) including a tube (14) sized for in vivo insertion into a patient and an ultrasound transducer (18) disposed at a distal end (16) of the tube. A camera (20) is mounted at the distal end of the tube in a spatial relationship to the ultrasound transducer. At least one electronic processor (28) is programmed to: control the ultrasound transducer and the camera to acquire ultrasound images (19) and camera images (21) respectively while the ultrasound transducer is disposed in vivo; construct keyframes (36) during in vivo movement of the ultrasound transducer, each keyframe representing an in vivo position of the ultrasound transducer and including at least ultrasound image features (38) extracted from at least one of the ultrasound images acquired at the in vivo position of the ultrasound transducer and camera image features (40) extracted from at least one of the camera images acquired at the in vivo position of the ultrasound transducer; generate a navigation map (45) of the in vivo movement of the ultrasound transducer comprising the keyframes; and output navigational guidance (49) based on comparison of current ultrasound and camera images acquired by the ultrasound transducer and camera with the navigation map.

Systems and methods for treating tissue may include one or more delivery devices, a grasping element, a first ring for anchoring to a wall of a gastrointestinal tract, and a second ring operably couplable to a radially inward surface of the first ring. Other embodiments include methods of treating tissues, including tubular tracts of tissue, comprising coupling a first ring to first tissue of a wall of a tissue tract, relocating a target tissue proximally to a position proximal to the first ring, coupling a second ring to the first ring, and cutting tissue proximal to the interface of the first and second rings.

Systems and methods for treating tissue may include one or more delivery devices, a grasping element, a first ring for anchoring to a wall of a gastrointestinal tract, and a second ring operably couplable to a radially inward surface of the first ring. Other embodiments include methods of treating tissues, including tubular tracts of tissue, comprising coupling a first ring to first tissue of a wall of a tissue tract, relocating a target tissue proximally to a position proximal to the first ring, coupling a second ring to the first ring, and cutting tissue proximal to the interface of the first and second rings.

A catheter-based imaging system comprises a catheter having a telescoping proximal end, a distal end having a distal sheath and a distal lumen, a working lumen, and an ultrasonic imaging core. The ultrasonic imaging core is arranged for rotation and linear translation. The system further includes a patient interface module including a catheter interface, a rotational motion control system that imparts controlled rotation to the ultrasonic imaging core, a linear translation control system that imparts controlled linear translation to the ultrasonic imaging core, and an ultrasonic energy generator and receiver coupled to the ultrasonic imaging core. The system further comprises an image generator coupled to the ultrasonic energy receiver that generates an image.

An upper gastrointestinal bleeding monitoring system includes a detection device and a signal processing device to determine bleeding condition of an upper gastrointestinal tract by using relation of time and intensity ratios of RGB three primary colors. The detecting device is placed to the upper gastrointestinal tract of a patient via his/her mouth or nasal passage and then stay the upper gastrointestinal tract for several days for detection of bleeding. The signal processing device may receive and display signal from the detection device to help medical professionals check if bleeding occurs in an upper gastrointestinal tract. Moreover, a procedure of determination of bleeding in an upper gastrointestinal tract with the upper gastrointestinal bleeding monitoring system is described.

An endoscope system includes an image acquisition section, an attention area setting section, and a dimming control section. The image acquisition section acquires a captured image that includes an object image. The attention area setting section sets an attention area within the captured image based on information from the endoscope system. The dimming control section performs a dimming control process that controls the intensity of illumination light based on the attention area set by the attention area setting section.

An endoscope system includes an image acquisition section, an attention area setting section, and a dimming control section. The image acquisition section acquires a captured image that includes an object image. The attention area setting section sets an attention area within the captured image based on information from the endoscope system. The dimming control section performs a dimming control process that controls the intensity of illumination light based on the attention area set by the attention area setting section.

Systems, methods, and apparatus for esophageal panometry are provided. An example method includes capturing measurement data including an area and a pressure of an esophageal body via a measurement device positioned with respect to the esophageal body; generating representations of the exported measurement data; analyzing the measurement data to determine esophageal reactivity based on the area and pressure; assessing esophageal function based on the determined esophageal reactivity; and outputting an indication of esophageal function.

Systems, methods, and apparatus for esophageal panometry are provided. An example method includes capturing measurement data including an area and a pressure of an esophageal body via a measurement device positioned with respect to the esophageal body; generating representations of the exported measurement data; analyzing the measurement data to determine esophageal reactivity based on the area and pressure; assessing esophageal function based on the determined esophageal reactivity; and outputting an indication of esophageal function.

A method of analysis using mass spectrometry and/or ion mobility spectrometry is disclosed comprising: (a) using a first device to generate smoke, aerosol or vapour from a target in vitro or ex vivo cell population; (b) mass analysing and/or ion mobility analysing said smoke, aerosol or vapour, or ions derived therefrom, in order to obtain spectrometric data; and (c) analysing said spectrometric data in order to identify and/or characterise said target cell population or one or more cells and/or compounds present in said target cell population.