A self-sampling device used for collecting a homogenized sample of cells from different areas within the vaginal canal by a user. The device, comprises a hollow, cylindrical elongated tubing, a cell collecting area which is covered by an adhesive collecting element is disposed at one end, a channel disposed along the length of the cell collecting area for collecting the cells from different areas along length of the vaginal canal via one insertion, so as to mix the cells within the channel resulting in the homogenized collection of cells, further the collecting element has plurality of organized ridges arranged along the length of the cell collecting area to facilitate cell collection and a handle comprising an ergonomically shaped finger grip, wherein one end of the finger grip having a design or marking to facilitate easy counting of the complete rotations of the device, the handle and the tubing is designed to form a unitary structure.

In an embodiment of the invention, a frictional tissue sampling device for obtaining a histological sample from an epithelial layer includes a platform with an axis, an abrasive material comprising a plurality of fibers associated with the platform, where the abrasive material is adapted to abrade the epithelial layer to dislodge the histological sample, where rotation of the platform around the axis rotates the abrasive material, and a collector material comprising a plurality of loops associated with the platform, where rotation of the platform around the axis rotates the collector material, where the collector material is adapted to collect the histological sample dislodged by the abrasive material, where contacting the platform with the epithelial layer and rotation of the platform moves the abrasive material and the collector material over the epithelial layer thereby obtaining the sample.

A universal single-handed device for self-collection of a biological sample is described herein. The single-handed device may comprise a sheath comprising a distal end for insertion into a portion of a user's body, a shaft at least partially within the sheath, having a collection head for collecting the biological sample positioned at the distal end thereof, and an actuator coupled to the shaft to transition the distal end between an open configuration and a closed configuration. The collection head is covered by the distal end in the closed configuration and is exposed when the distal end is in the open configuration.

Methods and devices for performing minimally invasive procedures useful for Fallopian tube diagnostics are disclosed. In at least one embodiment, the proximal os of the Fallopian tube is accessed via an intrauterine approach; an introducer catheter is advanced to cannulate and form a fluid tight seal with the proximal os of the Fallopian tube; a second catheter inside the introducer catheter is provided to track the length of the Fallopian tube and out into the abdominal cavity; a balloon at the end of the second catheter is inflated and the second catheter is retracted until the balloon seals the distal os of the Fallopian tube; irrigation is performed substantially over the length of the Fallopian tube; and the irrigation fluid is recovered for cytology or cell analysis.

Methods and devices for performing minimally invasive procedures useful for Fallopian tube diagnostics are disclosed. In at least one embodiment, the proximal os of the Fallopian tube is accessed via an intrauterine approach; an introducer catheter is advanced to cannulate and form a fluid tight seal with the proximal os of the Fallopian tube; a second catheter inside the introducer catheter is provided to track the length of the Fallopian tube and out into the abdominal cavity; a balloon at the end of the second catheter is inflated and the second catheter is retracted until the balloon seals the distal os of the Fallopian tube; irrigation is performed substantially over the length of the Fallopian tube; and the irrigation fluid is recovered for cytology or cell analysis.

Devices, systems and methods useable for useable for monitoring a physiological variable in a target tissue or body fluid located within the thorax of a subject by optical spectroscopy.

A sex toy collects a body fluid and/or cells as present in a genital, especially in a female vagina, for a diagnostic test, especially an in-vitro diagnostic test and/or a biomarker test. The sex toy includes a housing having at least one sampling port leading into at least one sampling channel for collecting a sample of body fluid and/or cells through the sampling port and the sampling channel inside the housing. The sex toy includes a test module adapted for analyzing and/or screening and/or monitoring diagnostic parameters of a collected sample body fluid and/or cells with medical implications as well as general health and lifestyle parameters. The test module includes comprising at least a first analyzing unit for carrying out a diagnostic test.

An excision apparatus for removing cellular tissue includes a housing provided with a fixation portion. The fixation portion is configured to be arranged on cellular tissue such that a closed space is formed by the cellular tissue and an inner surface of the fixation portion. The fixation portion is configured to fixedly retain the cellular tissue near the inner surface by removal of air from the closed space via an air evacuating means. The apparatus further includes a cutting element moveably arranged in the housing such that the cutting element is movable between a retracted position and an extended position with respect to the fixation portion. The cutting element includes an electrode arranged at a distal end of the cutting element and is configured for cutting a section of cellular tissue retained by the fixation portion when the cutting element is in the extended position.

Methods and devices for performing minimally invasive procedures useful for Fallopian tube diagnostics are disclosed. In at least one embodiment, the proximal os of the Fallopian tube is accessed via an intrauterine approach; an introducer catheter is advanced to cannulate and form a fluid tight seal with the proximal os of the Fallopian tube; a second catheter inside the introducer catheter is provided to track the length of the Fallopian tube and out into the abdominal cavity; a balloon at the end of the second catheter is inflated and the second catheter is retracted until the balloon seals the distal os of the Fallopian tube; irrigation is performed substantially over the length of the Fallopian tube; and the irrigation fluid is recovered for cytology or cell analysis.

An integrated scope and biopsy device having visualization for use in many different medical applications, such as, but not limited to, collection of uterine tissue biopsy is disclosed. The device may further include an integrated camera and light for visualizing the interior of the uterus and the tissue biopsy site itself. Further, the device is configured to evacuate tissue biopsies through aspiration and irrigation.