During a medical procedure, a transseptal fenestration is made at a septum of the heart and a shunt is implanted into the transseptal fenestration. During the same medical procedure, a transapical puncture is made into a left ventricle of the heart. A prosthetic valve is delivered via the transapical puncture and implanted at a mitral valve of the heart. Subsequently to delivering the prosthetic valve and making the transseptal fenestration, the transapical puncture is closed. Other embodiments are also described.

This invention relates to a medical device. The device includes an elongate cannula which is insertable into a blood vessel and which is resiliently biased towards a closed condition in which it inhibits fluid flow through the cannula. The cannula is displaceable away from its closed position by the introduction of a displacement arrangement such as a device or instrument or a pressurised fluid and reverts to its closed condition when the displacement arrangement is removed from the cannula to inhibit the flow of blood therethrough. The invention further relates to a needle for use with the medical device, to a kit and to a method of accessing a blood vessel. In addition, it relates to a method of closing an incision in a blood vessel and to a closure member for use in the method.

An apparatus includes an occlusion device operable to fit securely in an anatomical passageway within a head of a human. The occlusion device is configured to move unitarily with the head when the occlusion device is installed in the anatomical passageway. The occlusion device is further configured to prevent passage of fluid through the anatomical passageway when the occlusion device is installed in the anatomical passageway. A position sensor is fixedly integrated into the occlusion device. The position sensor generates signals indicating a position of the occlusion device in three-dimensional space, thereby indicating the position of the head in three-dimensional space. A connector communicatively coupled to the position sensor is operable to receive and transmit the signals generated by the position sensor.

A vascular closure device configured to seal a puncture site in the vessel wall in a more efficient manner is disclosed. The vascular closure device includes a guide member that extends through a portion of the sealing device and that is removable from the portion the sealing device.

Degree of occlusion is monitored for an occlusive device configured to occlude passage of fluid between two compartments in a lumenal space of a body of a patient. In some embodiments, changes in an electrical signal measured from the body of the patient are induced by perturbing the fluid; for example, by “tagging” a portion of fluid with a perturbation of temperature and/or composition. The degree of occlusion is estimated based on the measured changes. The electrical signal changes may be indicative of fluid movements redistributing the perturbed fluid among the two compartments; for example, by diffusion, mixing, and/or jetting of fluid.

An atrial shunt regulation device, a braid tool and a braid method thereof. The left disk (1) and the right disk (2) of the atrial shunt regulation device are connected via the intermediate portion (3) as a single piece, and the left disk (1), the intermediate portion (3) and the right disk (2) are braided by a single braid wire (10). The ends of the braid wires are secured by one nut in the single-braid method, which reduces the number and size of the nuts and easily forms a cortical layer. The braid tool for braiding an atrial shunt regulation device comprises a cylinder braid body mold (20), the cylindrical braid body mold (20) includes positioning pins (21) that are evenly connected to an outer wall of the braid body mold. The braid method of the atrial shunt regulation device comprises braiding, thermoforming, braiding a binding-off wire, securing ends of wires by a nut, and thermoforming again. The braid method is easy, the process is easy, and the device can be made manually in small batches to reduce costs.

A device, method, and use of a device for temporary management of a wound, such as a wound in a heart. The device has a shaft, a blood flow blocking membrane at the first end of the shaft for blocking blood flow through the wound, and an abutment member that is mounted to the shaft and is axially movable along the shaft towards and away from the blood flow blocking membrane for abutting the wound and holding the blood flow blocking membrane adjacent the wound. The blood flow blocking membrane is resiliently flexible and movable between at least a first collapsed state for inserting the blood flow blocking membrane through the wound, and a deployed state for blocking blood flow through the wound.

Some embodiments are directed to methods and systems for percutaneously treating dissections in a patient's vasculature, such as, without limitation, the aorta. The method can include deploying a catheter containing a collapsed anchoring element, frame, and cover through a first vessel to an entry point of the dissection. The anchoring element can be secured to the second branch vessel. The frame can be expanded in the first branch vessel. The cover can be unfolded over at least a portion of the entry point. The cover then reduces blood flow into the entry point.

Devices and methods for creating hemostasis at a subcutaneous vascular puncture are disclosed. The methods and devices may be used to close vascular punctures following trans-radial arterial procedures, e.g., catheterization and percutaneous coronary intervention. The devices may include a housing defining a suction chamber and an anvil disposed within the suction chamber and adhesively attached to the limb of a patient such that the apparatus creates a pulling force as well as a pushing force on the patient's skin, subcutaneous tissue, and artery. Alternatively, the pulling force and pushing force may be accomplished be mechanical means.

The present disclosure, when used by a live actor, may allow users to safely simulate hemorrhaging in some of the most challenging blood vessels in the most challenging anatomical locations such as the carotid artery, the axillary artery, and the femoral artery. The present disclosure may further provide the ability for users to safely perform hemorrhage control procedures, such as compression and ligation. The simulated wound of the present disclosure may be compressed to control hemorrhage. The simulated wound receptacle of the present disclosure may be packed with hemostatic or simple gauze to control hemorrhage. The simulated blood vessel of the device may be ligated with hemostats or other ligating instruments or material and bandaged with pressure dressings to control hemorrhage.