A device for treating a tissue opening includes a proximal portion including an elongated flexible member, a capsule releasably coupled to a distal end of the flexible member and including a lumen extending therethrough and a clip including a pair of arms movably housed within the capsule. A suture extending along a first one of the pair of arms and including a loop at a distal end thereof extending across an opening extending through the first one of the pair of arms. A suture grabbing element extending laterally from a second one of the pair of arms and including a hook so that, when the pair of arms are moved toward a closed configuration, the hook extends through the opening to grab the loop and draw the distal end of the suture from the first one of the pair of arms toward the second one of the pair of arms.

Medical devices for applying a cinch to a suture and methods for making and using such devices are disclosed. An example medical device may include an elongated shaft including a proximal region and a distal region. The distal region may define a lumen having a lumen dimeter, and a distally facing end surface. The medical device may also include an outer cinch member defining a bore and having an outer surface defining a shoulder. An elongated inner shaft may extend through and be longitudinally movable within the lumen and the bore and including a distal end section. An inner cinch member may be engaged with the distal end section of the elongated inner shaft.

An anchor for anchoring tensile members to bone includes: a housing extending along a central axis, with a hollow interior; a collet in the hollow interior having a central bore for accepting tensile members and an exterior surface, the collet being configured to swage around and against tensile members; a sleeve having a peripheral wall defining interior and exterior surfaces, the sleeve disposed in the housing's hollow interior axially adjacent to the collet, and movable parallel to the central axis between first and second positions; and wherein at least one of the collet exterior surface and the sleeve interior surface is tapered and the sleeve and the collet are arranged so movement of the sleeve from the first position to the second position causes the sleeve interior surface to bear against the collet exterior surface, causing the collet to swage radially inwards around and against one or more tensile members.

A rotatable jaw device for use with an endoscope and method of using a rotatable jaw device. The device includes a fork, and two jaws pivotally mounted to the fork. The jaws are movable between a predetermined closed position and a predetermined open position. At least one jaw has at least one protrusion on a surface of the jaw. The at least one protrusion prohibits movement of the two jaws in the opening direction beyond the predetermined open position. One jaw may have an elongated center void defined by twin jaw extensions, and the other jaw may rotate within the elongated center void when the two jaws move toward the predetermined closed position.

Apparatus for securing an object to bone, the apparatus including an anchor assembly comprising an anchor and an actuation element extending from the anchor, wherein applying a force to the actuation element when the anchor is disposed in a hole formed in a bone secures the anchor to the bone; and an inserter for deploying the anchor assembly in a hole formed in a bone, the inserter including a shaft for releasably engaging the anchor; and a force delivery mechanism mounted to the shaft and connected to the actuation element, the force delivery mechanism being constructed so as to receive an input force from an external source and to selectively apply an output force to the actuation element, with the force delivery mechanism being constructed so that the magnitude of the output force is limited regardless of the magnitude of the input force.

A forward-pushing for releasing suture locking device configured to fix a suture in a locking pin includes a collet and a thrust rod assembly sleeved outside the collet. The thrust rod assembly includes a thrust rod. A recessed portion is arranged at the thrust rod, and a protruding portion corresponding to the recessed portion is arranged at the collet. In a process that the thrust rod continuously moves distally in an axial direction, the thrust rod first pushes against a gradually raised side of the protruded portion, so as to allow the collet to deform to compress the locking pin, and allow the locking pin compressed by the collet to deform and fix the suture; and then the protruding portion is gradually accommodated in the recessed portion, so that at least part of deformations of the collet is restored to release the locking pin.

Extra-urethral implants and methods of use are disclosed. Implants can treat disorders or diseases of the prostate by, for example, enlarging the lumen of the prostatic urethra.

Methods and devices for transvascular prosthetic chordae tendinea implantation are disclosed. A catheter is advanced into the left atrium. From an atrium side, the catheter can be anchored to a superior surface of a mitral valve leaflet and a leaflet anchor can be advanced into the mitral valve leaflet to secure the mitral valve leaflet to a leaflet suture. A ventricular anchor is anchored to the wall of the ventricle to secure the ventricular wall to a ventricle suture. The leaflet suture and the ventricle suture may be tensioned and connected by a suture lock to form an artificial chordae.

A minimally invasive surgical suture end locking device includes a hooking assembly, a clamping structure, a power rod and an external conduit. The hooking assembly includes an annular structure enclosed by a flexible material and a force application end, the clamping structure is configured to press the locking pin, the power rod is configured to press the clamping structure by linear motion, and the external conduit is provided with a through hole, the through hole being provided on the side of a position where the clamping structure and the power rod contact each other for a portion of the suture passing through the through area to be led out. There is provided in the present invention a device that allows to tighten and lock the suture directly at the end proximal to the position where the suture is led out from the human tissue.

The present disclosure relates to a device for meniscal repair for use in areas of a human body where tissue can either be surgically reattached to bone or surgically repaired when a tear forms in the tissue. The device may take one of three forms; in a first form, the device comprises a handle and a deployment member permitting the deployment of anchors or sutures to the tissue requiring repair; subsequently the device may take a second form comprising the handle, still in place, and a cutter member for manipulating and cutting anchors and sutures to assist in repair of the tissue; in its third form, the device comprises the handle, still in place, and a fluid injection member for applying a fluid to aid in improving biological conditions for the tissue to heal.