A stapling assembly comprising an anvil, a staple cartridge, and a tissue cutting knife is disclosed. The staple cartridge comprises a longitudinal slot, a first group of staple cavities, a second group of staple cavities, staple drivers, and staples. The staples comprise a first group of staples positioned in the first group of staple cavities, and a second group of staples positioned in the second group of staple cavities. The first group of staples are deformed against the anvil to a first formed height by the staple drivers during a staple firing stroke. The second group of staples are deformed against the anvil to a second formed height by the staple drivers during the staple firing stroke. The second formed height is different than the first formed height. The tissue cutting knife is movable longitudinally within the longitudinal slot to drive the staple drivers during the staple firing stroke.

An end effector for use by a surgeon to staple an anatomical structure of a patient during a surgical procedure includes an anvil and a cartridge. Each of the anvil and the cartridge has a face that is positionable on the anatomical structure. The anvil is coupled to the cartridge at first and second ends. The anvil is movable relative to the cartridge to define a first gap between the faces at the first ends that is different from a second gap between the faces at the second ends.

A staple cartridge assembly for use with a surgical stapling instrument includes a staple cartridge including a plurality of staples and a cartridge deck. The staple cartridge assembly also includes a compressible adjunct positionable against the cartridge deck, wherein the staples are deployable into tissue captured against the compressible adjunct, and wherein the compressible adjunct comprises a first biocompatible layer comprising a first portion, a second biocompatible layer comprising a second portion, and crossed spacer fibers extending between the first portion and the second portion.

An end effector for stapling and cutting an anatomical structure includes an anvil, a cartridge, and a blade. The anvil has an anvil face and a plurality of staple pockets positioned on the anvil face. The cartridge has a cartridge face defining a cartridge blade channel, the cartridge being configured to retain a plurality of staples. Each of the plurality of staples comprises a first staple leg, a second staple leg, and a crown connecting the first and second staple legs and having a midpoint. Each of the plurality of staples comprises an open staple configuration and a closed staple configuration where a first portion of the first staple leg and a second portion of the second staple leg are bent relative to the crown such that the first portion of the first staple leg and the second portion of the second staple leg cross the midpoint of the crown.

A fastener cartridge can include, one, a cartridge body comprising a deck and a plurality of fastener cavities and, two, a plurality of fasteners positioned in the fastener cavities. The cartridge body can further comprise extensions extending from the deck having different sizes and/or configurations. The extensions can control the flow of tissue relative to the deck and/or support the fasteners as they are ejected from the fastener cavities.

A surgical stapling device includes tool assembly having an anvil and a cartridge assembly. The cartridge assembly includes a channel member that defines a cavity, a staple cartridge supported within the cavity of the channel member, and a biasing member. The staple cartridge supports staples, each having a back span and a pair of legs depending from the back span. The biasing member is positioned within the channel member and is deformable to allow the cartridge body to move vertically within the cavity of the channel member. The anvil incudes staple deforming pockets that are configured to deform the legs of the staples from a position within the same plane as the back span to positions laterally offset from the back span.

Embodiments include an end effector including an anvil, the anvil having an anvil face, an anvil blade channel defined by the anvil face, a first pocket row of first row staple pockets, a second pocket row of second row staple pockets, a third pocket row of third row staple pockets, a fourth pocket row of fourth row staple pockets, a fifth pocket row of fifth row staple pockets, a sixth pocket row of sixth row staple pockets, a cartridge having a cartridge face defining a cartridge blade channel, the cartridge being configured to retain a plurality of staples, and a blade, the blade having a cutting edge, where the blade is movable from a first position at a distal end of the cartridge to a second position at a proximal end of the cartridge.

A method of stapling tissue is disclosed. The method can include obtaining a staple cartridge including a plurality of staples, wherein each staple has a base and a leg extending from the base. The stapling method can also include firing the staples from the staple cartridge, wherein the staples are fired into tissue in a staple line. The staple line can include a first portion having a first flexibility and a second portion having a second flexibility, wherein the second flexibility is different than the first flexibility. A method of stapling tissue can also include adapting an anvil with an anvil plate having an arrangement of staple-forming pockets that differs from the staple-forming pockets in the anvil.

A surgical stapling instrument is disclosed. An end effector for the surgical stapling instrument comprises a staple cartridge assembly and an anvil. The staple cartridge assembly comprises a proximal end, a distal end, and a cartridge body comprising a shortened nose at the distal end. The staple cartridge assembly further comprises staples removably stored in the cartridge body, a driver configured to support at least one of the staples, and a sled movable toward the distal end. The sled comprises a ramp configured to lift the driver and at least one of the staples and a base, wherein the shortened nose of the cartridge body is shorter than the base of the sled. The anvil comprises a staple forming surface comprising a plurality of staple forming pockets and a blunt distal nose extending downward toward the staple cartridge assembly.

An end effector assembly for use with a surgical instrument is disclosed. The end effector assembly comprises a staple cartridge jaw, a threaded rod, and a replaceable staple cartridge configured to be seated in the staple cartridge jaw. The replaceable staple cartridge comprises a proximal end, a distal end, a longitudinal slot extending between the proximal end and the distal end, and a driver configured to support a staple, wherein the driver comprises a surface facing the threaded rod, wherein the surface comprises a clearance, and wherein at least a portion of the threaded rod is configured to be received in the clearance when the replaceable staple cartridge is seated in the staple cartridge jaw.