The present disclosure includes a device for retrieving foreign material within a blood vessel of a patient. Some foreign retrieval devices include an elongated body configured to be disposed within a catheter, the elongated body having a proximal end, and a distal end opposite the proximal end; and one or more arms, each arm having a proximal end coupled to the distal end of the elongated body, and a distal end extending toward the proximal end of the elongated body. In some foreign retrieval devices, each of the arms is configured to be actuated from a closed position to an open position.

Balloon/infusion catheters comprise internal corewires within a single lumen structure in which the corewire can slide relative to the catheter tube within limits, and the balloon is attached to the catheter tube on one end and to the sliding corewire on the other end. The lumen provides fluid to inflate the balloon and to infuse fluid into the vessel proximal to the balloon. The infusion ports can have a polymer valve to limit infusion to lumen pressures at which the balloon is appropriately inflated. The balloon/infusion catheter can have an integral flow meter near its proximal end. Corresponding methods for use of the balloon/infusion catheter are described, such as for the delivery of hydraulic forces when used in conjunction with an aspiration catheter.

a dilatable balloon catheter, comprising: a guide wire inserted and disposed in the inside of the catheter, an operation portion is fixedly connected to one end of the catheter, a balloon is disposed at the outer side of the catheter remote from the operation portion, the lumen of the catheter and the inner cavity of the balloon are connected by a communication structure provided on the catheter, the guide wire includes a first guide wire and a second guide wire which are separated from each other, the rear end of the first guide wire is connected to insertion-extraction structure in the rear end of the operation portion, the second guide wire is fixed to the inside of the catheter by a fixing process. The guide wire of the dilatable balloon catheter and the liquid injection lumen can share the same lumen, greatly reducing the diameter of the catheter in the present invention, so that the dilatable balloon catheter can be inserted into a narrow duct or lumen that needs to be expanded in human body through an device channel of an endoscope, and realize visualization operation.

A stent system according to the present invention is for use in retrieving a blood clot from the brain region and includes a wire; a first stent connected to a distal portion of the wire; a first outer sheath that covers and is fixed to a portion of the wire proximal to the first stent; and a second stent disposed on a portion of the wire proximal to the first stent, in which the second stent is configured to be movable toward or away from the first stent.

A vascular closure system includes a body portion, an anchor, at least one suture member, and a plurality of needles. The anchor assembly includes a hub and a wire assembly. The hub has at least one aperture defined in a sidewall thereof. The wire assembly includes an actuator member extending proximally through the body portion and hub, and at least one pre-formed wire having a free proximal end and a distal end that is connected to the actuator member. Withdrawing the actuator member extends the proximal end of the at least one pre-formed wire out of the at least one aperture to capture a portion of the vessel wall between the pre-formed wire and the body portion. The plurality of needles extend through the vessel wall adjacent to the vessel puncture and are configured to connect to the at least one suture member.

A rotational atherectomy device includes a drive shaft, a cutter mechanism coupled to the drive shaft and configured to cut occlusive material from a lesion, and a multi-stage macerator coupled to the drive shaft and configured to macerate cut occlusive material into a fine slurry. Successive stages of the multi-stage macerator macerate the cut occlusive material into successively smaller particles, which are moved proximally through a lumen of a sheath of the device that surrounds the drive shaft proximal to the macerator. The device may include a movable cutter mechanism guard that is passively rotatable between a first position in which it covers the cutter mechanism and a second position in which it exposes the cutter mechanism. One or more features of the device may limit a depth to which the cutter mechanism is able to cut the occlusive material to reduce a likelihood of undesirable tissue dissection.

An aspiration system exhibits an accelerated drop in negative pressure at the distal end of an aspiration catheter from the time of opening a valve. The system includes an aspiration pump in communication with a first chamber, and an aspiration catheter configured for placement into fluid communication with the first chamber by way of an elongate aspiration tube. A second chamber is provided between the aspiration tube and the catheter, and a valve is provided between the second chamber and the aspiration catheter. Upon opening of the valve with negative pressure at equilibrium in the first and second chambers, resistance to fluid flow between the second chamber and the distal end of the catheter is less than the resistance to fluid flow between the second chamber and the first chamber, causing a rapid aspiration into the second chamber.

A method of treating a lesion in a body lumen to enlarge a passageway in the lumen including providing a cutting member, connecting a tracking member to the cutting member to form an assembly, inserting the connected cutting member and tracking member through a first lumen of a catheter, withdrawing the catheter from the cutting member and tracking member, inserting the catheter over the tracking member and leaving the cutting member outside the catheter, and expanding a portion of the catheter to move the cutting member into cutting contact with the lesion. A device for treating a lesion in a body lumen including a cutting member having a coupler to connect a tracking member is also provided.

A clot removal device for removing a clot from a body vessel is presented. The device can facilitate clot retrieval by expanding in such a way as to engage the clot over a significant surface area. The clot can have at least one firm portion and at least one soft portion. At least one firm portion of the clot can be pinched by a proximal portion of the device while at least one soft portion of the clot can be retained by the distal portion of the device upon extraction. However, dislodgement and removal of the clot can cause softer portions the clot to shear or break, resulting in small floating fragments of clot in the vessel no longer attached to the main clot. This device can also capture and retain sheared or expanded distal portions of the clot upon removal of the clot from a vessel.

A mechanical thrombectomy device, and methods of manufacturing and using the mechanical thrombectomy device, are described. The mechanical thrombectomy device includes several clot arrestors independently mounted on a support wire. The clot arrestors have expandable frames that are eccentrically supported on the support wire. The independently and eccentrically mounted clot arrestors are arranged to allow a clot to pass into, and be captured by, one of the expandable frames. Furthermore, the independently and eccentrically mounted clot arrestors deform independently of one another such that retraction of the mechanical thrombectomy device through tortuous vasculature can stretch one clot arrestor without stretching another one of the clot arrestors to allow the clot to be retained by the unstretched clot arrestors. Other embodiments are also described and claimed.