Systems, instruments, and methods are described in which an apparatus comprises a housing including a scalpet device. The scalpet device includes a scalpet array that includes scalpets arranged in a pattern. The scalpets are deployable from the housing to generate incised skin pixels at a target site. The housing is positioned and the scalpet array is deployed into tissue at the target site. Incised skin pixels are generated when the target site is a donor site, and skin defects are generated when the target site is a recipient site. The incised skin pixels are harvested.

Systems, instruments, and methods for minimally invasive procedures including one or more of fractional resection, fractional lipectomy, fractional skin grafting, fractional scar revision, and/or fractional tattoo removal are described. Embodiments include instrumentation comprising a scalpet assembly coupled to a carrier, and the scalpet assembly includes a scalpet array. The scalpet array includes one or more scalpets configured for fractional resection, fractional lipectomy, fractional skin grafting, fractional scar revision, and/or fractional tattoo removal. The system includes a vacuum component coupled to the scalpet assembly and configured to evacuate tissue from the a site. The carrier is configured to control application of a rotational force and/or a vacuum force to the scalpet assembly.

The present invention relates to a joining member for an anastomosis system for realizing anastomosis between first and second hollow structures, such as end-to-side anastomosis. The joining member is annular and is adapted for joining the first and second hollow structures. The joining member includes a plurality of interconnected loops forming the annular body and a plurality of joining elements for joining the hollow structures connected to the annular body at locations where adjacent loops are interconnected to each other, and wherein the loops are configured to permit radial expansion of said annular body to expand said joining member from a first position to a second position having a second, larger diameter than the first position.

Methods and apparatus are provided for affecting an appearance of skin by harvesting small portions of tissue from a donor (first) site and applying them at a recipient (second) site. A plurality of micrografts can be formed from a piece of graft tissue and attached to a dressing material. The dressing material can then be expanded to increase a separation distance between the micrografts, and the dressing material having spaced-apart micrografts attached thereto can be applied to a prepared recipient site. An apparatus can be provided that expands the dressing material using a pressurized fluid. A further method can include providing a suspension of small portions of graft tissue in a solution. The solution can be injected into blisters formed at a recipient (second) site and the tissue portions allowed to attach and proliferate. A method and apparatus can also be provided for forming corresponding blisters at a donor site and at a recipient site. The raised (removed) portions of the blisters can be removed and attached to a dressing material, and the portions from the donor (first) site can be placed onto the exposed blister areas at the recipient site.

Systems and methods for controlling clinical soil are provided. A system includes a device cover formed of a flexible polymer sheet defining an interior volume for a skin grafting device, and includes at least a first opening configured to receive a portion of the skin grafting device. The system further includes a cincture having a gasket configured to be affixed to a perimeter of the first opening of the device cover and to secure the device cover about the first opening to the skin grafting device to inhibit fluid ingress into the interior volume of the device cover during a skin grafting process performed using the skin grafting device.

This disclosure details a surgical system and method for changing one or more dimensions of harvested tissue, such an autograft, which is harvested from one location in a patient's body and used for a surgical repair or reconstruction procedure in another location in the patient's body. An example surgical system includes a first press component defining a cavity configured to receive harvested tissue, and a second press component including a projection insertable into the cavity. Further, at least one of the first and second press components are made of a transparent or semi-transparent material such that when harvested tissue is in the cavity and when the projection is inserted into the cavity, the harvested tissue is visible through at least one of the first and second press components.

The present disclosure provides methods and devices for wound closure. In some exemplary embodiments, a tissue approximation device is provided. In some embodiments, the tissue approximation device includes a first scissors arm having a proximal end and a distal end and a second scissors arm having a proximal end and a distal end. In some embodiments, the second scissors arm is connected to the first scissors arm at a pivot point. In some embodiments, the tissue approximation device further includes a first rake member connected to the distal end of the first scissors arm via a first articulating joint. In some embodiments, the first rake member includes a plurality of hooks configured to grip tissue.

In one embodiment, a tissue planing assembly includes a base frame, a plurality of disassemblable components assembled to the base frame and having a ready configuration, a sample conveyor, a blade assembly configured to be coupled to the base frame, a control unit communicatively coupled to the sample conveyor, and one or more component sensors communicatively coupled to the control unit. The plurality of disassemblable components is configured to support a tissue sample. The sample conveyor is configured to convey the tissue sample through the blade assembly. The one or more components sensors are configured to output a signal indicative of at least one of the plurality of disassemblable components missing from the ready configuration, wherein the control unit prohibits operation of the sample conveyor when at least one of the plurality of disassemblable components is missing from the ready configuration.

Autografts are produced using material harvested from the patient without creation of a new wound. For example, material is harvested from the patient's very wound to which the autograft is to be applied.

Methods and apparatus are provided for affecting an appearance of skin by harvesting small portions of tissue from a donor (first) site and applying them at a recipient (second) site. A plurality of micrografts can be formed from a piece of graft tissue and attached to a dressing material. The dressing material can then be expanded to increase a separation distance between the micrografts, and the dressing material having spaced-apart micrografts attached thereto can be applied to a prepared recipient site. An apparatus can be provided that expands the dressing material using a pressurized fluid. A further method can include providing a suspension of small portions of graft tissue in a solution. The solution can be injected into blisters formed at a recipient (second) site and the tissue portions allowed to attach and proliferate. A method and apparatus can also be provided for forming corresponding blisters at a donor site and at a recipient site. The raised (removed) portions of the blisters can be removed and attached to a dressing material, and the portions from the donor (first) site can be placed onto the exposed blister areas at the recipient site.