A device for separating a sample of tissue in a controlled and precise manner and, more particularly, to produce a piece of tissue having a generally planar configuration and, optionally, additional desired characteristics, such as a predetermined maximum thickness, and selected tissue type. The device is adjustable to allow for different thicknesses and different operational speeds for application to different types of recovered tissue samples.

Embodiments include devices and methods configured to fractionally resect skin and/or fat. Fractional resection is applied as a stand-alone procedure in anatomical areas that are off-limits to conventional plastic surgery due to the poor tradeoff between the visibility of the incisional scar and amount of enhancement obtained. Fractional resection is also applied as an adjunct to established plastic surgery procedures such as liposuction, and is employed to significantly reduce the length of incisions required for a particular application. The shortening of incisions has application in both the aesthetic and reconstructive realms of plastic surgery.

The present invention relates to a method for producing skin grafts for rehabilitation of skin defects, where the method is carried out in a closed system operated and controlled in an automated manner.

Systems, instruments, methods, and compositions are described involving removing a portion of the epidermis within a donor site on a subject, and harvesting dermal plugs within the donor site. An injectable filler is formed by mincing the dermal plugs. The injectable filler is configured for injecting into a recipient site on the subject.

A process and system provides for atraumatic preparation of morselized Tissue Particles (TP)s, such as Full Thickness Skin Graft Particles (FTSGPs), cartilage particles and other organ tissue particles, in a liquid medium. The resultant tissue product may be a suspension of Tissue Particles in an aqueous solution and containing highly viable cells and may be rapidly prepared at bedside or in the operating room and conveniently delivered to a patient through a syringe or similar applicator. The morselized Tissues Particles may be used for surgical applications including wound healing, cosmetic surgery, and orthopedic cartilage repairs.

A skin mesher apparatus and method including a cover with a crank and a base attached to the cover which encloses a cutting roller and a propulsion roller wherein the cutting roller and propulsion roller are configured vertically align with each other to communicate with the crank and the cutting roller includes a stacked repeating pattern of a first cutting blade with teeth and notches and a second cutting blade with teeth and notches, wherein the second cutting blade is in a mirrored configuration to the first cutting blade.

A system may include a blade die, a first clamping caul positioned on a first side of the blade die, and a second clamping caul positioned on a second side of the blade die. A molding surface of the blade die and a molding surface of the first clamping caul may be configured to bend a first interchangeable blade positioned therebetween into a first shape in response to a first compression force. A second molding surface of the blade die and a molding surface of the second clamping caul may be configured to bend a second interchangeable blade positioned therebetween into a second shape in response to a second compression force.

The present disclosure provides methods and devices for wound closure. In some exemplary embodiments, a tissue approximation device is provided. In some embodiments, the tissue approximation device includes a first scissors arm having a proximal end and a distal end and a second scissors arm having a proximal end and a distal end. In some embodiments, the second scissors arm is connected to the first scissors arm at a pivot point. In some embodiments, the tissue approximation device further includes a first rake member connected to the distal end of the first scissors arm via a first articulating joint. In some embodiments, the first rake member includes a plurality of hooks configured to grip tissue.

An apparatus for automatically separating hair follicles includes a follicle separating unit configured to cut a skin tissue of a scalp cut from a back of a head of an alopecic patient in units of follicles and to classify follicles by a number of hairs included in each follicle in an incisional hair transplant or to classify follicles each directly extracted from the back of the head of the alopecic patient by the number of hairs included in each follicle in a non-incisional hair transplant, and a follicle separation control unit configured to control an operation of the follicle separating unit.

Systems, instruments, and methods for minimally invasive procedures including one or more of fractional resection, fractional lipectomy, fractional skin grafting, and/or fractional scar revision are described. Embodiments include instrumentation comprising a scalpet assembly coupled to a carrier, and the scalpet assembly includes a scalpet array. The scalpet array includes one or more scalpets configured for fractional resection, fractional lipectomy, fractional skin grafting, and/or fractional scar revision. The system includes a vacuum component coupled to the scalpet assembly and configured to evacuate tissue from the a site. The carrier is configured to control application of a rotational force and/or a vacuum force to the scalpet assembly.