Embodiments described herein are directed to a system for providing alternating freeze and thaw cycles. The system includes a controller, a vessel for holding a working fluid, a pressure generator, a cooler, a cooler heat exchanger, a heater, a heater heat exchanger, a check valve, and a treatment instrument. In some embodiments, the treatment instrument includes a distal end, a proximal end, a connecting portion adjacent to the proximal end, a needle element adjacent the distal end, a handle portion disposed between the proximal and distal end, and a depth-limiting element to limit an injection depth of the needle element.

A fractional handpiece and systems thereof for skin treatment include a passively Q-switched laser assembly operatively connected to a pump laser source to receive a pump laser beam having a first wavelength and a beam splitting assembly operable to split a solid beam emitted by the passively Q-switched laser assembly and form an array of micro-beams across a segment of skin. The passively Q-switched laser assembly generates a high power sub-nanosecond pulsed laser beam having a second wavelength.

The disclosure relates to a nozzle for a device for the dermo-cosmetic treatment of dark skin spots by cyto-selective cryotherapy comprising a spray jet supplied by a tank of pressurised liquified cryogenic gas. The nozzle comprises an upper ring for connecting to a shell, extended by a central body of which the side wall which narrows downwards has longitudinal openings and delimits a gas expansion chamber communicating with a frustoconical dispersal conduit arranged inside an end piece to be applied to the skin and opening to the outside through a discharge port.

Systems and methods utilizing RF energy to treat a patient's skin (e.g., dermis and hypodermis) or other target tissue including at a depth below a tissue surface (e.g., skin surface, mucosal surfaces of the vagina or esophagus) are provided herein. In various aspects, the methods and systems described herein can provide a RF-based treatment in which the deposition of RF energy can be selectively controlled to help ensure heating uniformity during one or more of body sculpting treatment (lipolysis), skin tightening treatment (laxity improvement), cellulite treatment, vaginal laxity or rejuvenation treatment, urinary incontinence treatment, fecal incontinence treatment, all by way of non-limiting examples. In various aspects, the systems can comprise one or more sources of RF energy (e.g., a RF generator), a treatment applicator comprising one or more electrode arrays configured to be disposed in contact with a tissue surface, and a return electrode (e.g., a neutral pad) to the tissue surface.

Embodiments include devices and methods configured to fractionally resect skin and/or fat. Fractional resection is applied as a stand-alone procedure in anatomical areas that are off-limits to conventional plastic surgery due to the poor tradeoff between the visibility of the incisional scar and amount of enhancement obtained. Fractional resection is also applied as an adjunct to established plastic surgery procedures such as liposuction, and is employed to significantly reduce the length of incisions required for a particular application. The shortening of incisions has application in both the aesthetic and reconstructive realms of plastic surgery.

A method and system for tattoo removal from a subject by exposing tattoo ink particles trapped within the dermis to a cold plasma is described herein. The tattoo removal method and system can be used to remove the tattoo from the skin of the subject being treated. In addition, the method and system described allows for the extraction of the tattoo ink particles, which may have toxic properties, from the subject's body.

A method of treating a patient with a therapeutic laser pulse includes applying a cooling mechanism to a first skin area, cooling a target skin area within the first the skin area from a first surface temperature to a second temperature through application of the cooling mechanism prior to application of the therapeutic laser pulse, initiating application of the therapeutic laser pulse at a first timepoint, while continuing to apply the cooling mechanism, determining a surface temperature of the target skin area a plurality of times during application of the therapeutic laser pulse at a refresh rate of 25 Hz to 400 Hz, and terminating the application of the therapeutic laser pulse at a second timepoint, based on the surface temperature determinations. Each of the plurality of surface temperature determinations occurs during a single therapeutic laser pulse duration from the first time point to the second timepoint.

An unattended approach can increase the reproducibility and safety of the treatment as the chance of over/under treating of a certain area is significantly decreased. On the other hand, unattended treatment of uneven or rugged areas can be challenging in terms of maintaining proper distance or contact with the treated tissue, mostly on areas which tend to differ from patient to patient (e.g. facial area). Delivering energy via a system of active elements embedded in a flexible pad adhesively attached to the skin offers a possible solution. The unattended approach may include delivering of multiple energies to enhance a visual appearance.

According to some embodiments, a method of treating a skin surface of a subject comprises heating a skin surface, abrading native skin tissue of a subject using a microdermabrasion device, wherein using the microdermabrasion device comprises moving the microdermabrasion device relative to the skin surface while simultaneously delivering at least one treatment fluid to the skin surface being treated and cooling the abraded skin surface.

The invention relates to a dispensing system for use in cryogenic skin treatment that is capable of targeted delivery of a cryogen at a high rate, thereby achieving rapid freezing of targeted skin tissue. The dispensing system of the present invention uses a cryogen that contains dimethyl ether and is designed to deliver the cryogen in an accurate and very effective manner.