A device for therapeutic neuromodulation in a nasal region can include, for example, a shaft and a therapeutic element at a distal portion of the shaft. The shaft can locate the distal portion intraluminally at a target site inferior to a patient's sphenopalatine foramen. The therapeutic element can include an energy delivery element configured to therapeutically modulate postganglionic parasympathetic nerves at microforamina of a palatine bone of the human patient for the treatment of rhinitis or other indications. In other embodiments, the therapeutic element can be configured to therapeutically modulate nerves that innervate the frontal, ethmoidal, sphenoidal, and maxillary sinuses for the treatment of chronic sinusitis.

A controller for a cooled radiofrequency ablation system is configured to sequentially activate a plurality of pump assemblies with a pump activation time delay between the activation of each of the plurality of pump assemblies, measure a temperature drop delay time for each of a plurality of cooled radiofrequency ablation probes, map each respective pump assembly of the plurality of pump assemblies to a corresponding cooled radiofrequency ablation probe of the plurality of cooled radiofrequency ablation probes based on the temperature drop delay time and an activation time of each of the plurality of pump assemblies, and confirm the mapping of each respective pump assembly to the corresponding cooled radiofrequency ablation probe by comparing, for each of the plurality of cooled radiofrequency probes, the measured temperature drop delay time to an expected temperature drop delay time.

A cooled radiofrequency ablation system and method are provided. In particular, a method to map active radiofrequency channels to respective pump assemblies for cooled radiofrequency ablation is provided. The system includes a pump system having a plurality of pump assemblies, a radiofrequency generator unit, and a plurality of cooled radiofrequency probes, wherein each cooled radiofrequency probe comprises a cable-tubing assembly having a radiofrequency cable connected to the radiofrequency generator unit and fluid tubing in communication with a pump assembly and connected to a cooling fluid source. Each pump assembly of the plurality of pump assemblies is activated individually in sequence. The system and method map each cooled radiofrequency probe to a respective pump assembly connected thereto by measuring a temperature drop delay time at the tip of each probe. The system and method can further detect the presence of multiple probes daisy-chained to a single pump assembly.

A variable length interstitial probe apparatus includes: a probe for effecting thermal therapy and/or cryotherapy to a tissue; a flexible umbilical sheath permanently affixed to the probe, including at least one interface for supplying energy, cooling fluid, cooling gas, heating fluid, and/or heating gas to the probe; and an adjustable depth stop configured to slide along a length of a shaft region of the probe, and lock to the shaft region at a selected position. The adjustable depth stop is configured to engage a probe driver and/or a skull mount apparatus to stabilize positioning of the probe and to control a depth of entry of the probe into a patient. The probe may be configured to effect temperature modulation therapy, where processing circuitry activates a modulation pattern of thermal therapy emission and cryogenic therapy emission for applying a thermal dose to the tissue.

A device for providing a cryotherapy ablation treatment includes a piping assembly and a snow horn adapted to create a spray of snow from a pressurized source of a low-temperature liquid, a tubular applicator for collecting a mass of snow at a prescribed density that is sufficient to allow the mass to serve as the needed, low temperature, thermal reservoir for the device after the applicator's distal end has been disconnected from the snow horn end so that it can to be used during the treatment process, and an applicator tip adapted to allow it to connect to the applicator's distal end and be used to treat those specific locations which are to receive this treatment.

Systems for treating a subject's tissue can include a thermally conductive cup with vacuum features configured to facilitate removal of air located between the cup and the subject's skin. The vacuum features can extend along cup to provide airflow paths to a vacuum port. The applicator can cool and/or heat the retained tissue to affect targeted tissue. After the treat period, the vacuum can be reduced or stop and the applicator can be removed from the subject.

The present invention generally relates to improved medical devices, systems, and methods. In many embodiments, devices, systems, and methods for locating and treating a target nerve with integrated cold therapy and electrical stimulation systems are provided. For example, nerve stimulation and cryoneurolysis may be delivered concurrently or alternately with the cryo-stimulation device. In some embodiments, the device may be operated by a single operator or clinician. Accordingly, embodiments of the present disclosure may improve nerve targeting during cryoneurolysis procedures. Improvements in nerve localization and targeting may increase treatment accuracy, physician confidence in needle placement during treatment, and clinical efficacy and safety. In turn, such improvements may decrease overall treatment times, the number of repeat treatments, and the re-treatment rate. Further, additional improvements in nerve localization and targeting may reduce the number of needle insertions, applied treatment cycles, and may also reduce the number of cartridge changes.

Present disclosure provides a cooling device with safety features and methods for controlling temperature of the cooling device for safe cooling of target surface.

Embodiments relate to illuminated electrosurgical devices and related systems and methods. An electrosurgical device can include an electrosurgical blade having a proximal end and a distal end and comprising a plurality of light elements. A plurality of separation walls and a plurality of apertures can be arranged relative to the plurality of light elements to guide light from the plurality of light elements to illuminate an area around the distal end of the electrosurgical blade.

Present disclosure provides a cooling device with safety features and methods for controlling temperature of the cooling device for safe cooling of target surface.