To provide a chemical ablation device that enables simple performance of chemical ablation treatment including pre- and post-treatment potential measurements. A chemical ablation device according to the present invention includes an electrode-equipped guidewire (30) with which intracardiac potential is measurable, an over-the-wire balloon catheter (40) having a guidewire lumen (415) into which the electrode-equipped guidewire (30) is to be inserted, a Y-shaped connector (50) connected to a proximal side of the balloon catheter (40) and including a guidewire port (51) and an expansion port (53), and a hemostasis valve (60) connected to the guidewire port (51) of the Y-shaped connector (50) and including a side-infusion tube (65) for supplying ethanol to the guidewire lumen (415) of the balloon catheter (40). The ethanol supplied to the guidewire lumen (415) of the balloon catheter (40) is ejected from an opening of a distal tip (47).

An apparatus includes a shaft, a balloon, a tip member, and a heating feature. The tip member is distal to the balloon and has a larger outer diameter than the shaft. The heating feature is operable to ablate tissue of the Eustachian tube contacting the balloon in the expanded state. The heating feature may include an illuminating element and a photosensitive coating on the balloon. Alternatively, the heating feature may include a thermal heating element that heats the balloon inflation fluid and thereby heats the wall of the balloon. Another apparatus includes a shaft, a tip member, and an electrode assembly. The electrode assembly includes a plurality of electrodes positioned along the shaft near the distal end, proximal to the tip member. The electrodes are spaced apart from each other along a longitudinal axis and are operable to apply RF energy to tissue to thereby ablate the tissue.

Thermochemical ablation techniques may provide ablation of bodily tissue using chemical reaction energy.