Various embodiments provide an electrosurgical instrument for delivering electromagnetic (EM) energy and ultrasonic vibrations for treating biological tissue. The electrosurgical instrument comprises: an instrument shaft arranged to convey EM energy and an electrical signal for driving a magnetostrictive ultrasound transducer; a distal end assembly arranged at a distal end of the instrument shaft to receive the EM energy from the instrument shaft and deliver the EM energy from the distal end assembly for tissue treatment; and a magnetostrictive ultrasound transducer arranged to receive the electrical signal from the instrument shaft and generate ultrasonic vibrations around the distal end assembly for tissue treatment. Other embodiments provide an electrosurgical generator, and an electrosurgical apparatus comprising the instrument and generator.

An electrosurgical apparatus and method for performing thermal treatment in the gastrointestinal tract, e.g. to ablate duodenal mucosal tissue. The apparatus comprises an instrument having a flexible cable and an applicator suitable for use with a gastroscope, which can be deployed within a patient to delivery energy in a targeted or otherwise controllable manner. The applicator can deliver microwave energy by radiation. The direct and depth-limited nature of microwave energy can be make it more effective than treatments that rely on thermal conduction. The applicator may include a radially extendable portion arranged to move an microwave energy delivery structure into contact with duodenal mucosal tissue at the treatment region. The applicator may comprise any of a balloon, bipolar radiator, movable paddle, and rotatable roller element.

A method for determining a change of temperature of an object. The method may include heating an object and measuring scattering parameters (S-parameters) of scattered microwave electric fields from the object. A distorted Born iterative method may be used to determine a change of a dielectric property of the object based on the measured S-parameters. A change of temperature of the object may be determined based on the change of the dielectric property of the object.

A microwave ablation probe includes a cable comprising an antenna configured to deliver Radio Frequency (RF) energy to a target zone and a cooling path defined by a first channel and a second channel configured to circulate cooling fluid in the probe. The inner tube also comprises a choke formed thereon configured to reduce RF energy reflected away from the antenna.

A multicarrier ablation system comprising: an antenna for application to biological tissue; a multi-carrier signal generator configured to provide a forward radio frequency (RF) signal to the antenna, the forward RF signal comprising multiple subcarriers that occupy respective frequencies within a bandwidth of the RF signal; and a monitoring circuit configured to receive a reflected RF signal from the antenna and control the multi-carrier signal generator to adjust one or more parameters of the forward RF signal during an ablation procedure based on the reflected RF signal.

The device includes an outer conductor and an inner conductor arranged approximately coaxial with each other. The outer conductor surrounds the inner conductor. The outer conductor and the inner conductor are arranged and configured to generate an electromagnetic field with lines of force extending from a front surface of the inner conductor to a front surface of the outer conductor. The device further includes an energy delivery window arranged in front of the outer conductor and the inner conductor.

A flexible microwave ablation antenna and a microwave ablation needle including the same are disclosed. The flexible microwave ablation antenna including: a radiator for transmitting microwave for ablation; a coaxial cable for propagating the microwave for ablation generated by a microwave generator to the radiator; wherein the flexible microwave ablation antenna is bendable. Preferably, an annular composite structure is disposed around a periphery of the coaxial cable to suppress the electromagnetic wave from propagating along the coaxial cable in a reverse direction. The annular composite structure includes an annular non-metallic layer and an annular metallic layer surrounding the annular non-metallic layer. The annular metallic layer is electrically insulated from the coaxial cable.

A system for neuromodulation includes a split-ring resonator (SRR) comprising a resonance circuit, the SRR being implantable in a cranial target site and a source of microwave signals, wherein the microwave signals are deliverable wirelessly to couple with the SRR to produce a localized electrical field, wherein the localized electrical field inhibits one or more neurons at the cranial target site with submillimeter spatial precision.

The present invention relates to comprehensive systems, devices and methods for delivering energy to tissue for a wide variety of applications, including medical procedures (e.g., tissue ablation, resection, cautery, vascular thrombosis, treatment of cardiac arrhythmias and dysrhythmias, electrosurgery, tissue harvest, etc.). In certain embodiments, systems, devices, and methods are provided for delivering energy to difficult to access tissue regions (e.g. peripheral lung tissues), and/or reducing the amount of undesired heat given off during energy delivery.

An electrosurgical apparatus and method for performing thermal treatment in the gastrointestinal tract, e.g. to ablate duodenal mucosal tissue. The apparatus comprises an instrument having a flexible cable and an applicator suitable for use with a gastroscope, which can be deployed within a patient to delivery energy in a targeted or otherwise controllable manner. The applicator can deliver microwave energy by radiation. The direct and depth-limited nature of microwave energy can be make it more effective than treatments that rely on thermal conduction. The applicator may include a radially extendable portion arranged to move an microwave energy delivery structure into contact with duodenal mucosal tissue at the treatment region. The applicator may comprise any of a balloon, bipolar radiator, movable paddle, and rotatable roller element.