A thulium fiber laser system can be used to treat tissues based on the ability for quick changes between laser pulses. For example, to treat stones in a tissue, a long pulse having low peak power can be used to create bubbles in front of the stone (calculi), then follow a series of shorter pulses and higher peak power can be used to break the stone. The sequence can be repeated to maintain large bubble formation, with the long pulse characteristics changed to accommodate for the changes in the tissue. A fluorescent sensing assembly can be used to detect the tissue conditions for selecting the conditions of the thulium fiber laser.

A system and method for detecting relative location of a surgical laser fiber tip relative to a surgical laser target during a surgical laser procedure utilizes a spectrophotometer to detect radiation indicative of the relative location. For example, the detected radiation may indicate contact between the fiber tip and a stone being subjected to laser lithotripsy, so as to prompt the surgeon to withdraw the fiber tip from the stone and/or take other action to limit contact-induced erosion of the fiber tip, and to avoid saturation of the endoscope camera resulting from the flash that occurs following contact. In addition, the absence of any detected radiation by the spectrophotometer may be used to indicate that the stone is no longer present, or that the fiber tip is no longer aimed at the stone, prompting the operator to reposition the fiber and/or temporarily cease firing of the laser. The main surgical laser may be a pulsed Holmium laser, which is delivered to the target through the optical fiber together with a pulsed 532 nm aiming beam.

A laser system includes a first laser configured to generate a laser light, the first laser light including a first wavelength, a second laser configured to generate a second laser light, the second laser light including a second wavelength different from the first wavelength, and a laser fiber operatively coupled to each of the first laser and the second laser to emit at least one of the first laser light or the second laser light at a target site.

A system for ablation of tissue has at least a guideplate having a front surface and a rear surface. The guideplate has multiple guideholes distributed over the front surface and passing from the front surface to the rear surface. The at least three longitudinally advancing laser emitters are on elongated supports. The at least three longitudinally advancing laser emitters on elongated supports have a diameters that allow their passage through the guideholes on the guideplate. Each of the three laser emitters has a projection area for emission of laser energy; and the projection areas for each of the three laser emitters overlapping only a portion of the projection areas for at least two others of the three laser emitters when the at least three laser emitters lie within a single geometric plane. Moving the laser emitters while active devascularizes changing volumes of tumor tissue.

Devices and systems used to ablate tissue of a tumor using laser energy are disclosed. The devices and systems include a laser probe and a magnetic resonance (MR) safe temperature probe. The MR safe temperature probe includes an optical sensor. A bone anchor fixture separates the laser probe and the MR safe temperature probe to prevent interference in the MR safe temperature probe data. Proton Resonance Frequency (PRF) thermometry is used to model a temperature of a pixel of an MR image located adjacent the optical sensor. The modeled pixel temperature and the measured temperature are compared and monitored. Exceeding a threshold difference value causes an intervening action to occur.

A system and method for detecting relative location of a surgical laser fiber tip relative to a surgical laser target during a surgical laser procedure utilizes a spectrophotometer to detect radiation indicative of the relative location. For example, the detected radiation may indicate contact between the fiber tip and a stone being subjected to laser lithotripsy, so as to prompt the surgeon to withdraw the fiber tip from the stone and/or take other action to limit contact-induced erosion of the fiber tip, and to avoid saturation of the endoscope camera resulting from the flash that occurs following contact. In addition, the absence of any detected radiation by the spectrophotometer may be used to indicate that the stone is no longer present, or that the fiber tip is no longer aimed at the stone, prompting the operator to reposition the fiber and/or temporarily cease firing of the laser. The main surgical laser may be a pulsed Holmium laser, which is delivered to the target through the optical fiber together with a pulsed 532 nm aiming beam.

The present disclosure generally relates to the field of laser based medical devices. Particularly, but not exclusively, the present disclosure relates to an apparatus and method for enhancing laser beam efficacy in a liquid medium. In many embodiments, laser pulses are modulated based on bubble dynamics to improve energy delivery to a target. A variety of exemplary pulse modulation scheme are described including modulating pulse power down during expansion of an index bubble and modulating pulse power up during collapse of the index bubble.

Laser ablation devices and related systems and methods may have laser outputs with multiple wavelengths. Laser ablation devices may include a laser energy source that can emit two or more laser outputs with different wavelengths. Some laser ablation devices include a processor to control the laser energy source to cause the laser energy source to emit a target wavelength blend with the laser outputs.

The present invention relates to Fiber Feedback (FFB) technology, and provides a method and system for estimating distance between a fiber end and a target. The method includes illuminating, by a Light Emitting, Transmitting and Detecting (LETD) system, the target with laser light of different wavelengths having low and high-water absorption coefficients, using different laser light sources, as well as receiving a returned signal corresponding to the incident laser light of different wavelengths, and detecting the returned signal to measure intensity values of the returned signal of a specific wavelength. Using the measured intensity values, a processing unit may estimate distance between the fiber end and the target. The present invention enables accurate estimation of distance between a fiber end and a target, and also provides a robust distance estimation technique which is compatible with different types of targets.

Dermatological systems and methods for providing a picosecond laser treatment a plurality of treatment wavelengths, at least one of which is provide by an optical parametric oscillator (OPO) capable of providing picosecond laser pulses at a wavelength in the red region of the visible electromagnetic spectrum for treating one or more target tissue types. In some embodiments, the OPO is capable of providing picosecond laser pulses at a wavelength in one of the near-infrared and the infrared region of the electromagnetic spectrum.