Systems and methods for sonicating a body within an organ of a patient include supplying ultrasound energy to the body in order to produce a liquified material, which can then be aspirated from the body via a catheter. Image guidance is used during aspiration of the liquified material.

A drill guide fixture may be configured to prepare a skull for attachment of a cranial insertion fixture. The drill guide fixture may include a central drill guide and a bone anchor guide at a base of the drill guide fixture. The central drill guide may define a central drill guide hole therethrough, wherein the central drill guide hole has a first opening at a base of the drill guide fixture and a second opening spaced apart from the base of the drill guide fixture. The bone anchor drill guide may define a bone anchor drill guide hole therethrough, and the bone anchor drill guide hole may be offset from the central drill guide hole in a direction that is perpendicular with respect to a direction of the central drill guide hole. Related cranial insertion fixtures, robotic systems, and methods are also discussed.

A guide tube is used for guiding an instrument through a hole within tissue of a patient. The guide tube includes a cannula member defining a passage extending therethrough along an axis. The passage is operable to receive the instrument and guide the instrument through the hole within the tissue of the patient. The guide tube also includes an expansion member that is moveably coupled to the cannula member to selectively move radially between a retracted position and an expanded position relative to the axis of the cannula member. The expansion member is at least partially insertable into the hole when the expansion member is in the retracted position. The expansion member is operable to engage with a surface of the hole when the expansion member is in the expanded position.

An access system having a communication component that interfaces with a first device and a second device, where the first device is located inside or on an entity and coupled to a biological organism of the entity, and where the second device is located outside the entity and a controller component that controls a function of the first device, employing the communication component, to provide treatment to the biological organism of the entity coupled to the first device based on a request received from the second device.

An optical imaging system for imaging a target during a medical procedure, the optical imaging system involving a first camera for capturing a first image of the target, a second wide-field camera for capturing a second image of the target, at least one optional path folding mirror disposed in an optical path between the target and a lens of the second camera, and a processor for receiving the first image and the second image, the processor configured to apply an image transform to one of the first image and the second wide-field image and combine the transformed image with the other one of the images to produce a stereoscopic image of the target.

A computing device having a first processor configured to receive three-dimensional imaging data acquired by an imaging system, the three-dimensional imaging data being from ahead of a subject. The first processor can be configured to determine vascular structures from the three-dimensional imaging data, generate a three-dimensional model of the head of the subject from the three-dimensional imaging data, the three-dimensional model of the head including a three-dimensional model of the vascular structures and a three-dimensional model of a portion of a frontal horn of the subject, determine an entry point on the three-dimensional model of the head of the subject, determine a plurality of trajectories, each trajectory intersecting the three-dimensional model of the portion of the frontal horn and does not intersect the three-dimensional model of the vascular structures, and each trajectory is linear, and select a final trajectory from the plurality of trajectories.

An auxiliary tool for surgery includes an auxiliary tool main body part, and a first leg pair located on the auxiliary tool main body part. A tail end of the first leg pair is connected to the auxiliary tool main body part, a first mounting part is formed at a front end of the first leg pair, and the first mounting part is configured to clamp and press a surgical device to place the surgical device in a predetermined position.

An introducer system for use with a navigation probe. The introducer system has an introducer and a probe retainer configured to selectively connect to the introducer. The probe retainer includes a receiver configured to receive a navigation probe shaft and limit movement of the navigation probe shaft in the lateral direction. A first clamp and a second clamp are connected to the receiver with the receiver located between the first clamp and the second clamp. Each of the first clamp and the second clamp is selectively engageable with respective portions of the introducer sidewall to hold the receiver at a fixed location relative to the introducer. The receiver, the first clamp, and the second clamp are configured to provide a visual path through the probe retainer and into the introducer passage.

A system for aspirating thrombus and delivering an agent includes an aspiration catheter having a supply lumen having a proximal end, a distal end, and a wall, and an aspiration lumen having a proximal end, an open distal end, and an interior wall surface adjacent the open distal end, and at least one orifice at or adjacent the distal end of the supply lumen, in fluid communication with the aspiration lumen and located proximally of the open distal end of the aspiration lumen, wherein the at least one orifice is configured to create a spray pattern that is caused to impinge on the interior wall surface of the aspiration lumen such that the spray pattern upon impinging on the interior wall surface is caused to transform into at least a substantially distally-oriented flow capable of exiting the open distal end of the aspiration lumen.

Disclosed is a drug injection device that is implanted between the skull and the subcutaneous layer of an animal. The disclosed drug injection device includes: a main body that is positioned on the skull and implanted and fixed in the subcutaneous layer; a guide member that guides a trocar such that the drug is injected into brain parenchyma inside the skull of the animal; a cover member that is installed inside the main body and connected to the guide member in the center and has a hole for guiding drug injection trocar so as to be inserted; and a sealing member that is installed between the main body and the cover member and prevents reverse flow of drugs and the introduction of foreign substances.