Kits, diagnostic systems and methods are provided, which measure the distribution of colors of skin features by comparison to calibrated colors which are co-imaged with the skin feature. The colors on the calibration template (calibrator) are selected to represent the expected range of feature colors under various illumination and capturing conditions. The calibrator may also comprise features with different forms and size for calibrating geometric parameters of the skin features in the captured images. Measurements may be enhanced by monitoring over time changes in the distribution of colors, by measuring two and three dimensional geometrical parameters of the skin feature and by associating the data with medical diagnostic parameters. Thus, simple means for skin diagnosis and monitoring are provided which simplify and improve current dermatologic diagnostic procedures.

A method for site assessments of a catheter insertion site and/or dressing includes: scanning the catheter insertion site and/or dressing with an image capture device and/or sensor; selecting a patient baseline site location and skin tone; recording a baseline condition using a computing device; determining a site assessment rate using a computing device; prompting a clinician to make a site assessment of the catheter insertion site and/or dressing using a computing device; and recording site assessment information in an electronic medical record using a computing device.

The invention relates to a method for adjusting and/or calibrating a medical microscope, the following being implemented for at least one observer beam path of the medical microscope: capturing respective image representations of an object at different magnification levels of a zoom optical unit, and determining a zoom center using the captured image representations as a starting point, and i) capturing respective further image representations at different axis positions of at least one linear or rotational movement axis of the medical microscope, a rotation of the capture device relative to the at least one linear or rotational movement axis being determined using the captured further image representations as a starting point, and/or ii) capturing respective further image representations of the object in different focal planes and/or at different working distances in the case of an off-centered imaging optical unit, a rotation of the capture device being determined using the captured further image representations as a starting point, and a reference marking being determined using the determined zoom center and the determined rotation as a starting point and being provided for adjustment and/or calibration purposes. Further, the invention relates to a medical microscope.

A retinal imaging system is provided. The system comprises: a fundus camera having a focusing mechanism; an imaging module configured for imaging user's face and eyes and providing image date indicative of a relative orientation between an optical axis of the fundus camera and a line of sight of user's eye at user's eye target position; a position and alignment system configured and operable to utilize the image data indicative of said relative orientation for positioning the fundus camera at an operative position such that the optical axis substantially coincides with the line of sight of user's eye, to enable focusing the fundus camera on the retina; a sensing system comprising one or more sensors, configured and operable for monitoring a user's face position with respect to a predetermined registration position and generating corresponding sensing data; and a safety controller configured and operable to be responsive to the sensing data, and upon identifying that the user's face position with respect to the predetermined registration position

A process for calibrating a glucose sensor under sterile conditions includes providing separate, sterile, glucose-containing calibration fluids, each having a different glucose concentration, and in turn providing these fluids to a sensing zone containing a sensing probe of a glucose sensor. Each solution is typically, in turn, propelled into the sensing zone, thus flushing out used fluid already present in the sensing zone. The process provides rapid calibration of a glucose sensor in a sterile fashion and is therefore appropriate for point-of-use calibration.

A method for obtaining a spatial pattern of an anatomical structure of a subject includes comprising the steps of a) acquiring, from at least one digital image capturing device, at least one uncalibrated image of a calibration reference applied on a surface configured to receive the subject, the calibration reference having at least one known dimension and defining at least one known direction; b) defining an absolute calibrated reference system of three coordinates based on the calibration reference depicted in the at least one uncalibrated image; and c) acquiring, from the at least one digital image capturing device, at least a first and at least a second calibrated image of a plurality of markers applied on a corresponding plurality of body landmarks of the anatomical structure of the subject at respective contact points with the body landmarks, the plurality of markers being arranged within the absolute calibrated reference system,

A biological information measurement apparatus comprises: a spectrometer; a housing that contains the spectrometer and includes a surface on which a measurement target is to be placed, and an aperture portion through which light illuminating the measurement target placed on the surface and light reflected from the measurement target are to pass; and a shutter member that can move between a first position of opposing the aperture portion of the housing and a second position of retreating from the first position of opposing the aperture portion, the shutter member including a white reference surface. If the shutter member is at the first position, the spectrometer performs calibration using the white reference surface. If the shutter member is at the second position, the aperture portion and the measurement target oppose each other, and the spectrometer colorimetrically measures the measurement target.

Methods and devices are disclosed for calibrating intensity of a light source in a system of evaluating a skin lesion using Elastic-Scattering Spectroscopy (ESS). The ESS system may illuminate a sample of the skin lesion with a pulse from the light source adjusted to a high output setting, receive a signal comprising an elastic scattering spectrum from illuminating the skin lesion sample at the high output setting, determine whether the received signal has an intensity that is greater than a saturation threshold associated with at least one optical detection sensor, and if so, store the elastic scattering spectrum from illuminating the skin lesion sample at the high output setting. If not greater than the saturation threshold, the ESS system may illuminate the skin lesion sample with a pulse from the light source adjusted to a low output setting, receive a signal comprising an elastic scattering spectrum from illuminating the skin lesion sample at the low output setting, and store the elastic scattering spectrum from illuminating the skin lesion sample at the low output setting.

Methods and apparatuses for heart rate detection are described. In one example, a headphones apparatus and method includes emitting a first light in a first light direction directed at a left ear location from a left ear light emitter, and detecting a detected first light at a left ear light detector following interaction of the first light with a left ear tissue. The method includes emitting a second light in a second light direction directed at a right ear location from a right ear light emitter, the right ear location different from the left ear location. The method further includes detecting a detected second light at a right ear light detector following interaction of the second light with a right ear tissue, and estimating a heart rate from the detected first light and the detected second light.

A system for imaging and examination of a cervix, comprising a control module connectable with a changeable head configured to image the cervix and collect a tissue biopsy, the head selected from a group consisting of a digital colposcope module, a transvaginal optical probe module and an endo-cervical endoscope module. The system may additionally comprise light source(s) to illuminate cervix tissue; sensing device(s) to generate signal(s) from light and/or to acquire image(s) of a portion of a cervix; and processor(s) in communication with the sensing device(s). The system is configured to: (i) analyze the signal(s); (ii) detect the size of the cervix; (iii) determine parameters defining properties of the cervix; (iv) determine and distinguish normal tissue from abnormal tissue within the cervix; (v) determine the location of area(s) of abnormal tissue in the cervix; and (vi) generate a panoramic view of the cervix.