Delivery system for fixation device, including guide catheter with proximal end portion having proximal end port, distal end portion having distal end port, and inner surface defining inner lumen extending in fluid communication between proximal end port and distal end port. Delivery catheter extending through the inner lumen to define annular space between outer surface of the delivery catheter and inner surface of the guide catheter. A pressure sensor proximate the proximal end portion in fluid communication with the annual space to monitor fluid pressure. The distal end portion of the guide catheter includes flow passages in fluid communication between an exterior of the distal end portion and the annular space.

A multiple-point basket-type or crown-shaped catheter device provides simultaneously mapping over a three-dimensional (3D) region of a subject, such as, one or more chambers of a subject's heart. The catheter device may include a series of splines each having a wave-like profile formed of a periodic series of peaks and troughs, with electrodes located at the peaks and troughs for mapping purposes.

A catheter including one or more echogenic members facilitate guiding the catheter to a selected locations within a patient using ultrasound imaging. The echogenic members may include expandable members, such as balloons, be positioned near a distal end of the catheter. The echogenic members include an echogenic material, such as a coating or a fluid, that is configured to enhance the diffuse sound scattering of the echogenic member. An expanded echogenic member is detectable using ultrasound imaging.

Methods and systems for use of the Q-wave to R-wave interval to guide placement of a leadless cardiac pacemaker are disclosed. An implant delivery device is equipped with sensing electrodes to sense R-wave onset in a ventricle of a patient's heart to allow placement at a location of last or latest onset of the R-wave. Guidance tools are provided to assist in determination of the Q-wave to R-wave interval during implantation. For a chronic system, a cooperative approach is disclosed in which an implantable medical device and a leadless cardiac pacemaker exchange data to determine Q-wave to R-wave intervals and enhance cardiac resynchronization therapy delivery by the leadless cardiac pacemaker.

A deep intracranial electrode which comprises a flexible wire, an electrode contact, a connector and a shield sleeve, one end of the flexible wire is connected to the electrode contact, the other end connected to the connector; the shield sleeve sheathes around the flexible wire, a sum of a length of a part of the flexible wire arranged outside the shield sleeve and a length of the shield sleeve being adjustable. When the shield sleeve sheaths around the flexible wire, the length of the flexible wire inside the radio-frequency magnetic field of the magnetic resonance equipment may equal to a sum of the length of the shield sleeve and a length of the flexible wire outside the shield sleeve.

This invention relates to an aneurysm occluder, and more particularly but not exclusively, to an endovascular aneurysm occluder that can be inserted into an aneurysm cavity by using endovascular surgical procedures. The aneurysm occluder has a deformable housing and an absorber or material that causes blood clotting made of an absorbent material in or attached to the housing.

A system that provides an independent and agnostic cardiovascular sensing ability that can be deployed prior to the standard treatment methods for blocked cardiovascular arteries, and placed in the zone of a vascular lesion for treatment, placing sensors that can monitor blood and vessel specificity to manage the acute and long term biologic reaction to the treatment zone communicating information for analytical management and decision processing to an external or internal receiving station.

Disclosed is a stent-mesh and microelectrode assembly that is deployable using a catheter or cannula to form a neural interface for recording and/or stimulation of neural tissue. In some embodiments, the assembly may include a thin-film microelectrode array attached to a spring-like stent-mesh component. The thin-film microelectrode array may include an electrode body having two lateral wing-like appendages located distal to a thin-film flexible cable that terminates at the proximal end in a thin-film connector region. The stent-mesh may be attached to the thin-film microelectrode array and configured to be advanced to a target area in a collapsed state and then expanded after reaching the target area to transition the thin-film microelectrode array to a deployed configuration. Accordingly, the assembly may deliver the thin-film microelectrode array to a target area in a minimally invasive manner.

A method for determining a location of an arrhythmogenic foci (632) in or near a heart (101) includes the steps of positioning a locator assembly (100) within the heart (101), the locator assembly (100) including a plurality of electrodes (102) that receive electrical signals from the heart (101), generating a first signal array (733) from the electrical signals received by the plurality of electrodes (102) to determine an actual location of the arrhythmogenic foci (632), artificially stimulating the heart (101) based on the actual location determined by the first signal array (733) to generate a second signal array (733), and confirming the actual location of the arrhythmogenic foci (632) by comparing the first signal array (733) with the second signal array (735). In some embodiments, the locator assembly (100) includes a plurality of bipolar electrodes (102).

Devices, systems, and methods for remotely monitoring physiologic cardiovascular data are disclosed. At least some of the embodiments disclosed herein provide access to the external surface of the heart through the pericardial space for the delivery of the sensor to the epicardial surface of the heart. In addition, various disclosed embodiments provide for a memory device capable of receiving the physiologic cardiovascular data collected by the sensors and transmitting such data wirelessly to a remote location.