This disclosure relates to a method of manufacturing an in vivo analyte sensing device, which is adapted for detecting at least one analyte in a body fluid or tissue and an in vivo analyte sensing device obtainable by said manufacturing method. Further, this disclosure relates to a method of manufacturing a sensor base plate and a sensor base plate obtainable by said manufacturing method. The sensor base plate may be used for the manufacture of an in vivo analyte sensing device.

Ablation electrode assemblies include an inner core member and an outer shell surrounding the inner core member. The inner core member and the outer shell define a space or separation region therebetween. The inner core member is constructed from a thermally insulative material having a reduced thermal conductivity. In an embodiment, the space is a sealed or evacuated region. In other embodiments, irrigation fluid flows within the space. The ablation electrode assembly further includes at least one thermal sensor in some embodiments. Methods for providing irrigation fluid during cardiac ablation of targeted tissue are disclosed that include calculating the energy delivered to irrigation fluid as it flows within the ablation electrode assembly through temperature measurement of the irrigation fluid. Pulsatile flow of irrigation fluid can be utilized in some embodiments of the disclosure.

One variation of a system for collecting biosignal data includes: a left junction; a right junction; a first band spanning the left and right junctions; a first band adjuster configured to adjust a length of the first band between the left and right junctions; a second band spanning the left and right junctions and radially offset from the first band about a lateral axis spanning the left and right junctions; a second band adjuster configured to adjust a length of the second band between the left and right junctions; a first electrode fixedly mounted to the first band and centered between the left and right junctions; a second electrode mounted to the first band offset from the first electrode and laterally-adjustable along the length of the first band; and a third electrode mounted to the second band and laterally-adjustable along the length of the second band.

The present disclosure provides systems, apparatuses, and methods for use of wearable electrode assemblies. The electrode assemblies improve comfort by providing increased overall surface area of their bottom surfaces, which make contact with the patient's scalp and hair. Collapse, compression, or telescoping of the bottom surface will thereby decrease the direct force and/or pressure applied by the distal member or members of the bottom surfaces to the skin. This may be advantageous in patients who have little to no hair in electrode contact areas, patient populations that are particularly skin-sensitive, and/or patients which must wear the electrode assemblies of an extended time period. The electrode assemblies further include structures to dispense and/or maintain conductive gel placed over the patient's skin, thereby maintaining electrical connection quality, and/or to facilitate the clearing of skin and/or hair prior to establishing an electrical connection.

A method of controlling a wearable device including a signal generator, two stimulation electrodes, and two sensing electrodes to monitor a level of edema of a subject, includes generating, by the generator, a signal that causes a current to flow between the stimulation electrodes and measuring an impedance between the sensing electrodes disposed on a skin of the subject at an interval of time during a testing period, thereby providing impedance measurements, validating each impedance measurement against a model set of impedance measurements, eliminating a measurement from the impedance measurements if the measurement fails the validating, thereby providing a validated sub-set of impedance measurements, converting each of the validated sub-set of impedance measurements to an edema index, thereby providing edema indices, averaging the edema indices and generating an average edema index for the testing period, and generating an alert depending on the average edema index.

An oximeter measures oxygen saturation for two or more different tissue depths and shows these results on a screen. A probe of the oximeter has multiple different distances between source and detector sensors. One probe implementation has fixed sensor positions. Other implementations include sensors on a moveable platform or openings to accept sensors, which allow a user to vary a distance between sensors.

The invention relates to a system for determining blood flow within a blood vessel (18). A fluid infusion unit (4, 10, 11) continuously infuses a fluid into the blood vessel, and a temperature values determining unit (14, 21) determines simultaneously a first temperature value at a first location and a second temperature value at a second location such that the first temperature value is indicative of the temperature of the fluid and the second temperature value is indicative of the temperature of a mixture of the fluid and the blood. The blood flow is determined based on the measured first and second temperature values and the infusion rate. This kind of determining the blood flow leads to an increased accuracy and is less cumbersome than known techniques requiring a movement of a temperature sensor for measuring temperatures at different locations.

A method of measuring signals from a surface. The method comprises: placing on the surface a flexible sensing device having an array of coated electrodes, wherein at least one electrode of the array is metallic and is at least partially coated by a polymer; and collecting signals from the sensing device.

A method for configuring a myoelectrically controlled prosthetic system with a prosthesis socket and several lead electrodes for recording electric muscle activities, featuring the steps: placement of a surface electrode arrangement comprising several surface electrodes around the circumference of a residual limb, recording of electric muscle activity in muscles of the residual limb as electromyograhic signals, the activity being recorded by the surface electrodes, evaluation of the myoelectric signals with regards to the distinctness of the signals, selection of the control procedure that is to be used to control the prosthesis system, based on the evaluation of the distinctness of the signals, and fixing of the lead electrodes to the prosthesis socket.

This patent application provides a method and equipment for promoting measurement of movement of substances/bolus in a tubular organ and for use in the impedance phase reading in the esophagus, thus integrating the field of exams performed for medical diagnoses, particularly for carrying out in the esophagus. The method is characterized by taking the difference between tension and current (impedance phase) as a parameter in the Impedance audiometry exam, from an excited element with alternate current; the proposed method uses a probe (5) defined by a flexible insulating catheter (1), including metallic rings (2) that is introduced in the organ (3) to be examined; the metallic rings (2) are connected by wires (4) that run internally through the probe (5) defined by the flexible insulating catheter (1); the probe (5) is connected to an equipment (6) that applies an electric excitation to the metallic rings (2) which act as electrodes.