A sensing system for sensing a potential complication at a venous catheter site. The system includes a sensor module for attachment at the site of the catheter. The sensor module includes a pressure sensor configured to generate pressure data representing measured pressure at the site of the catheter; a temperature sensor configured to generate temperature data representing measured temperature at the site of the catheter; and two pairs of bio impedance electrodes that generate bioelectrical signals representing bioelectrical activity at the site of venous catheter and a transmitter for transmitting the pressure, temperature data and bio impedance data. The system also includes a computing device configured to receive the response signal that includes the generated pressure, temperature and bio impedance data; and transmit the pressure temperature and bio impedance data to a user device for comparing the generated pressure temperature bio impedance data to threshold values indicative of intravenous complications.

Methods, systems, and coaptation measurement devices as described herein include an elongate sensor body at the end of a proximal connecting member, and a plurality of sensors in an array across a face of the sensor body, wherein each sensor of the plurality of sensors is configured to detect if a portion of a heart valve is in contact with the sensor.

The present invention relates to an electrocardiogram measurement apparatus (measurement sensor) which can be used in combination with a smartphone by an individual. The electrocardiogram measurement apparatus according to the present invention comprises: two amplifiers for receiving electrocardiogram signals from a first electrode and a second electrode; one electrode driving unit; a third electrode for receiving an output of the electrode driving unit; an A/D converter connected to an output terminal of each of the two amplifiers and converting analog signals into digital signals; a microcontroller for receiving the digital signals from the A/D converter; and a communication means for transmitting the digital signal, wherein: the microcontroller is supplied with power from a battery; the microcontroller controls the A/D converter and the communication means; and each of the two amplifiers amplifies one electrocardiogram signal so as to simultaneously measure two electrocardiogram signals.

Disclosed are devices and methods for estimating blood pressure, which implement a pulse-transit-time-based blood pressure model that can be calibrated. Some implementations provide reliable and user friendly means for calibrating the blood pressure model using blood pressure perturbation methods and multiple sensors.

Analyte sensors and methods of manufacturing same are provided, including analyte sensors comprising multi-axis flexibility. For example, a multi-electrode sensor system 800 comprising two working electrodes and at least one reference/counter electrode is provided. The sensor system 800 comprises first and second elongated bodies E1, E2, each formed of a conductive core or of a core with a conductive layer deposited thereon, insulating layer 810 that separates the conductive layer 820 from the elongated body, a membrane layer deposited on top of the elongated bodies E1, E2, and working electrodes 802′, 802″ formed by removing portions of the conductive layer 820 and the insulating layer 810, thereby exposing electroactive surface of the elongated bodies E1, E2.

Remote monitoring of a subject wearing a sports helmet is enabled. In one aspect, an example system includes a safety helmet and a sensor integrated with the helmet for continuously gathering head acceleration force data, the head acceleration force data associated with the head movements of a subject. The system can also include a wireless transceiver coupled to the sensor for transmitting the head acceleration force data and a mobile device for receiving the head acceleration force data from the wireless transceiver. The system can further include a database engine for displaying the head acceleration force data to a user.

An apparatus is suitable for measuring a photoplethysmogram (PPG). A photoplethysmographic sensor apparatus may include a casing defining a surface, a plurality of optical emitters configured to emit radiation extending from the surface, at least one photo sensor configured to capture radiation emitted by at least a subset of the plurality of optical emitters. At least a first measurement configuration and a second configuration is defined by the plurality of optical emitters and the at least one photo sensor such that the first and the second measurement configuration provide different measurement channels by including at least partially different sets of at least one optical emitter and at least one photo sensor. The first and second measurement configurations define different spatial configurations, each of which is line symmetric with respect to an imaginary line along the surface.

A catheter may include electrodes for transvascular nerve stimulation. The electrodes may be positioned within lumens of the catheter and aligned with apertures in the outer wall of the catheter. The electrodes may produce focused electrical fields for stimulation of one or more nerves. In one embodiment, the catheter may include a set of proximal electrodes and a set of distal electrodes, and the proximal electrodes may stimulate a patient's left phrenic nerve and the distal electrodes may stimulate a patient's right phrenic nerve.

Devices and methods for vascular navigation, assessment and/or diagnosis are disclosed where a location detection system generally includes an elongate body defining a lumen at least partially along a length of the elongate body. One or more sensors are positioned near or at a distal tip of the elongate body and one or more openings are defined along the elongate body in proximity to the one or more sensors. The one or more openings are configured to control a boundary distance between the one or more sensors and a fluid with a parameter of a known initial value when emitted from the one or more openings. A controller is in communication with the one or more sensors and is configured to track a change in the parameter relating to concentration over the one or more sensors and determine a position of the one or more sensors within a body.

Systems and methods for measuring and monitoring intracavitary tissue temperature. The system may include a catheter shaft with a circuit board disposed therein, the circuit board having an array of sensors disposed thereon. The catheter shaft may have an opening and an expandable structure surrounding the opening to provide a field of view of the intracavitary tissue for the array of sensors through the opening. The system may include a software-based programming system run on a computer such that a clinician may review information indicative of temperature of the intracavitary tissue, and be alerted if the temperature exceeds a predetermined threshold.