The disclosed apparatus, systems and methods relate to devices, systems and methods for intra-operative imaging.

The present invention provides a breast computed tomography system in which the body motion and the pain of an examinee during capturing of images of the breast are reduced. The breast computed tomography system includes a gantry accommodating a light emitting unit that radiates light onto the breast. The gantry includes a gripper having a right gripping portion and a left gripping portion.

an object information acquiring apparatus comprises a light emission unit configured to emit light beams from a plurality of emission positions; a conversion unit configured to convert acoustic waves generated when an object is irradiated with the light beams emitted by the light emission unit into electric signals; a beam profile acquisition unit configured to acquire information relating to beam profiles of the light beams emitted by the light emission unit, the beam profiles corresponding respectively to the plurality of emission positions; and a characteristic information acquisition unit configured to acquire characteristic information of the object on the basis of the information relating to the beam profiles corresponding to the plurality of emission positions and the electric signals.

A breast cancer diagnosis system includes a probe that sequentially outputs light of a plurality of wavelengths of a near-infrared area to a target object, receives reflected light, and sequentially processes the reflected light; a central control device that receives optical data of the reflected light sensed by the probe, calculates a concentration of chromophore of the target object for each chromophore, and generates an image of the chromophores indicating a distribution of the concentration value of each chromophore; and a display that outputs the image, in which in the probe, one or more channel signal processing units including one or more light irradiation modules and light collection modules may be disposed, and each of the channel signal processing units sequentially operates so that each of the channel signal processing units may generate the optical data of the reflected light.

The present invention provides compositions and methods for imaging tumor resections.

This invention is a smart bra for optical scanning of breast tissue which has light emitters which transmit light into breast tissue, light receivers which receive the light after it has been transmitted through the breast tissue, and expandable components which selectively move light emitters and/or receivers closer to the surface of a breast where there are air gaps.

A method for determining a view angle of a thermal image from a user and generating a suggestion to enable the user for adaptive positioning of a subject for capturing the thermal image is provided. The method includes (i) receiving a thermal image of a body of a subject, (ii) automatically determining a view angle of the thermal image from a user using a view angle estimator, (iii) determining an angular adjustment to be made to a view position of the thermal imaging camera or a position of the subject by comparing the determined view angle with a required view angle as per thermal imaging protocol when the thermal image does not meet the required view angle and (iv) generating instructions to the user for adjusting the view position of the thermal imaging camera for capturing a new thermal image at the required view angle as per thermal imaging protocol.

The present disclosure relates to compounds that are useful as near-infrared fluorescence probes, wherein the compounds include i) a pteroyl ligand that binds to a target receptor protein, ii) a dye molecule, and iii) a linker molecule that comprises an amino acid or derivative thereof. The disclosure further describes methods and compositions for incorporating the compounds as used for the targeted imaging of tumors. Conjugation of the amino acid linking groups increase specificity and detection of the compound. Methods and compositions for use thereof in diagnostic imaging are contemplated.

The medical imaging apparatus of the present invention includes a bath tank for accommodating a test subject, the test subject being at least a portion of a body of a human subject; a measurement device movable in a predetermined direction, the measurement device including ab group of elements to emit a radiation wave into the bath tank and receive a scattered radiation wave; and a control unit for measuring by the measurement device when at least one of a location of the test subject within a plane orthogonal to the predetermined direction, a location of the test subject in the predetermined direction, and continuity of data measured by the measurement device satisfies a predetermined condition. Because of this configuration, the medical imaging apparatus is able to acquire data covering the entire measurement target site.

The present invention provides compositions and methods for imaging tumor resections.