A method to visualize, display, analyze and quantify angiography, perfusion, and the change in angiography and perfusion in real time, is provided. This method captures image data sequences from indocyanine green near infra-red fluorescence imaging used in a variety of surgical procedure applications, where angiography and perfusion are critical for intraoperative decisions.

Disclosed are various embodiments for integrated diffuse correlation spectroscopy. A first control signal can be sent to a switch to cause an integrator to integrate a current from a photodiode. An integrated current can be received from the integrator, and a data signal can be sent to a computing device based at least in part on the integrated current. A second control signal can be sent to a switch to cause the integrator to cease integrating the current from the photodiode.

Systems and methods are provided for non-invasive measurement of endogenous S-nitrosothiols and related measurements thereof. One or more sensors non-invasively measures a set of one or more biometric parameters within a region of interest of a subject to provide a time series of measurements for each of the set of biometric parameters. A medium stores machine-readable instructions that are executable by an associated processor to perform processing comprising receiving the time series of measurements of the biometric parameter, generating, using a predictive model, a value representing an endogenous S-nitrosothiol content of tissue within the region of interest from the time series of measurements of the biometric parameter, and providing, by a user interface, the value representing the endogenous S-nitrosothiol content of tissue within the region of interest to a user.

Disclosed herein are systems, methods, and devices for calibrating contrast measurements from laser speckle imaging systems to accurately determine unknown particle motion characteristics, such as flow rate. The calibration stores to memory calibration data, which may include a set of measurements from samples with known particle characteristics and/or estimates of noise, including the effects on contrast arising from undesired signals unrelated to the unknown particle motion characteristics. The calibration data may be accessed and used to correct an empirical measurement of contrast and/or interpolate a value of the unknown particle motion characteristic. The system may include a light source, photodetector, processor, and memory, which can be combined into a single device, such as a wearable device, for providing calibrated flow measurements. The device may be used, for example, to measure blood flow, cardiac output, and heart rate, and can be used to amplify the pulsatile signal.

A method of displaying an operational parameter of a surgical system is disclosed. The method includes receiving, by a cloud computing system of the surgical system, first usage data, from a first subset of surgical hubs of the surgical system; receiving, by the cloud computing system, second usage data, from a second subset of surgical hubs of the surgical system; analyzing, by the cloud computing system, the first and the second usage data to correlate the first and the second usage data with surgical outcome data; determining, by the cloud computing system, based on the correlation, a recommended medical resource usage configuration; and displaying, on respective displays on the first and the second subset of surgical hubs, indications of the recommended medical resource usage configuration.

Embodiments herein relate to reflective optical medical sensor devices. In an embodiment, a reflective optical medical sensor device including a central optical detector and a plurality of light emitter units disposed around the central optical detector is provided. A plurality of peripheral optical detectors can be disposed to the outside of the plurality of light emitter units. Each of the plurality of peripheral optical detectors can form a channel pair with one of the plurality of light emitter units. The reflective optical medical sensor device can also include a controller in electrical communication with the central optical detector, the light emitter units, and the peripheral optical detectors. The controller can be configured to measure performance of channel pairs; select a particular channel pair; and measure a physiological parameter using the selected channel pair. Other embodiments are also included herein.

A medical imaging system is described that comprises an heating element configured to apply at least one heating pattern element to a material to locally heat the material; a sensor configured to capture the position of the heated material a predetermined time after the application of the heating pattern element; and circuitry configured to determine the change of the heating pattern applied to the material based upon the captured position of the heated material after the predetermined time.

An electronic device according to an embodiment includes a speaker capable of outputting a sound wave, a sensor capable of acquiring an optical signal related to blood flow at a measured part of a user, and a controller configured to measure blood flow information of the measured part based on the optical signal. The controller estimates a sleep state of the user based on the blood flow information and controls, based on the sleep state, a sound wave outputted from the speaker.

Non-contact biological sensors 1, 2 that detect biological information of a person by electromagnetic waves are provided in a seat 10 on which the person sits. The biological sensors 1, 2 are disposed in the seat 10 at positions away from members A1, A2, A3 (22, 32) which are the members, from among the members that constitute the seat 10, that interfere with the passage of electromagnetic waves. The biological sensors each have a first sensor 100 and a second sensor 200 that emit electromagnetic waves of different frequencies towards the person, and the first sensor 100 is disposed adjacent to the second sensor 200. Due to this configuration, it becomes easier to accurately detect biological information.

A photonic integrated device comprising: a photonic integrated chip (PIC) adapted to investigate blood flow at a portion of tissue of a user, said PIC comprising: a laser having an optical output, or waveguide for guiding an optical output from an external laser, the optical output being split into a first optical component and a second optical component; wherein the first optical component is arranged to be transmitted to and generate speckle at the portion of tissue of the user; the photonic integrated device further comprising: one or more detectors, each detector configured to receive the speckle generated by the first optical component at the portion of tissue; and one or more optical splitters optically coupling the second optical component to one or more respective input(s) of the one or more detectors; wherein the photonic integrated device is further adapted to measure interference at the one or more detectors between a sample arm formed by the first optical component and a reference arm formed by the second optical component.