The invention comprises an elongated device adapted for insertion, including self-insertion, through the body, especially the skull. The device has at least one effector or sensor and is configured to permit implantation of multiple functional components through a single entry site into the skull by directing the components at different angles. The device may be used to provide electrical, magnetic, and other stimulation therapy to a patient's brain. The lengths of the effectors, sensors, and other components may completely traverse skull thickness (at a diagonal angle) to barely protrude through to the brain's cortex. The components may directly contact the brain's cortex, but from there their signals can be directed to targets deeper within the brain. Effector lengths are directly proportional to their battery size and ability to store charge. Therefore, longer angled electrode effectors not limited by skull thickness permit longer-lasting batteries which expand treatment options.

Aspects of the disclosure can provide a method and device for detecting EEG signals of a first person in proximity to the device. The device can include a non-contact EEG directional circuit having non-contact sensors, the non-contact EEG directional circuit being configured to detect the EEG signals produced by a brain of the first person without making contact with the first person. The device can further include a processor coupled to the non-contact EEG directional circuit that is configured to analyze the EEG signals to detect patterns in the EEG signals that correspond to a state of the first person in proximity to the non-contacting sensor and feedback device that is configured to provide a second person with an indication of the state of the first person in proximity to the non-contacting sensor. Additionally, the device can include a contact EEG circuit having sensors that are in contact with the second person and that is configured to detect second EEG signals produced by a brain of the second person, wherein the processor is coupled to the contact EEG circuit and is configured to analyze the second EEG signals to detect patterns in the second EEG signals that correspond to a state of second the person.

The disclosed embodiments include systems and methods to provide a patient suffering from at least one communication and memory impairment with positive stimuli. In one of such embodiments, the method includes obtaining data indicative of a current condition of a first patient. The method also includes determining, based on prior patient data of the first patient, a first stimulus that triggered a positive response from the first patient while the first patient was in a condition similar to the current condition. The method further includes providing a first recommendation for the first patient to experience the first stimulus for display on an electronic device. The method further includes receiving a first response triggered by the first stimulus. The method further includes storing data indicative of the first response in a storage medium.

A method for functional analysis of neurophysiological data by decomposing neurophysiological data and EEG signal to form a plurality of signal features. The signal features may then optionally be analyzed to determined one or more patterns.

Disclosed is a method for scoring in real time neural signals of a subject with respect to a reference state characterized by k=1 . . . K reference covariance matrices, the method including the following steps: (i) obtaining neural signals from the subject; (ii) computing a covariance matrix of the neural signals; (iii) computing the Riemannian distances between the covariance matrix and k=1 . . . K reference covariance matrices; (iv) computing a continuous score s in real time based on at least one of the distances computed in step (iii). Also disclosed is a system and method for self-paced modulation or external modulation of neural activity of a subject.

Certain examples provide systems and methods to enhance slow wave sleep. An example method includes identifying a sleep stage for slow wave sleep in a subject being monitored. The example method also includes generating, following identification of slow wave sleep and using a processor including a phase locked loop, an output signal based on a phase of a reference input signal, the output signal phase locked according to the reference input signal. The example method includes delivering, during slow wave sleep for the subject, a stimulus to the subject based on the phase locked output signal. The delivering includes providing the stimulus in a series of signal pulses for a first period of time; and providing a refractory period without pulses in a second period of time. The method further includes measuring feedback from the stimulus.

A brain training system and method are provided that incorporates a first phase and a second phase of brain training. The first phase is designed to increase attention by requiring the completion of an attention-based activity or task. This may require the identification of match or mismatched images. The second phase is designed to increase working memory by requiring the completion of a working memory-based task that requires the repetition of an illumination sequence. Each phase may be implemented in a self-contained handheld device, similar to the shape of a tablet, or may be implemented in a computer application, such as software. The answers of each phase are recorded in a central database and the system may provide recommendations based on the answers.

A portable monitoring device comprises a hearing aid having a housing, a microphone (24), an acoustic signal processing means (43), and an acoustic output transducer (33). The portable monitoring device further comprises an EEG monitoring system arranged at least partly in said housing, and comprising a measuring unit (3) having electrodes (12) arranged external to the housing. The EEG monitoring system comprises a processing unit (42) for analyzing the EEG signal for identifying or predicting specific biological incidences, such as a seizure, in said person, decision means for deciding, based on said analyzed EEG signal, when an alarm or information must be provided to said person, and means for providing said alarm or information through said output transducer (33). The invention further provides a method of monitoring an EEG signal of a hearing impaired person.

Provided are methods of enhancing the performance of a subject on a cognitive task by improved self-regulation of internal distraction. The methods include presenting a computer-based cognitive training program to a subject, where performance of the subject on the cognitive task is enhanced by the cognitive training program. Computer readable media and devices useful for practicing the methods of the present disclosure are also provided.

A neurostimulation device includes a plurality of electrodes adapted to be electrically connected to a subject to receive multichannel electrical signals from the subject's brain, a multichannel seizure detection unit electrically connected to the plurality of electrical leads to receive the multichannel electrical signals, and a neurostimulation unit in communication with the multichannel seizure detection unit. The plurality of electrodes are at least three electrodes such that the multichannel electrical signals are at least three channels of electrical signals, and the multichannel seizure detection unit detects a presence of a seizure based on multichannel statistics from the multichannel electrical signals including higher order combinations than two-channel combinations.