Disclosed is an antenna device for measuring biometric information by using a leaky wave. The antenna device according to an embodiment may include an antenna main body formed to surround at least some portion of the body having a target analyte. The antenna main body may include a plurality of transmission-side slots and a plurality of reception-side slots formed on a surface surrounding the body portion. An electromagnetic wave is excited inside the antenna main body may be radiated to an inside of the body portion through at least one of the plurality of transmission-side slots. Information on an analyte within the body portion may be sensed based on a frequency of an electromagnetic wave received through at least one of the plurality of reception-side slots via the body portion.

The present disclosure relates to noninvasive methods, devices, and systems for measuring various blood constituents or analytes, such as glucose. In an embodiment, a light source comprises LEDs and super-luminescent LEDs. The light source emits light at at least wavelengths of about 1610 nm, about 1640 nm, and about 1665 nm. In an embodiment, the detector comprises a plurality of photodetectors arranged in a special geometry comprising one of a substantially linear substantially equal spaced geometry, a substantially linear substantially non-equal spaced geometry, and a substantially grid geometry.

Method and system for providing basal profile modification in insulin therapy for use with infusion devices includes periodically monitoring the analyte levels of a patient for a predetermined period of time in order to determine, based on the monitored analyte levels, an appropriate modification factor to be incorporated into the underlying basal profile which was running at the time the periodic monitoring of the analyte levels were performed.

Systems, methods, apparatuses, and devices, for the wireless communication of analyte data are provided. In some embodiments, a method and calibration station for calibrating a continuous analyte sensor system is provided. Methods and testing systems for testing a continuous analyte sensor system is provided. Continuous analyte sensor systems, display devices and peripheral devices configured for wireless communication of analyte, connection, alarm and/or alert data and associated methods are provided.

A fully or partially implantable analyte sensor for continuously monitoring analyte concentration in a body fluid has a substrate with a first surface configured to face towards the body fluid. The sensor has a working electrode and an interferent electrode. The interferent electrode and the working electrode are electrically separated layers located adjacently on the first surface. The sensor has a further electrode, the further electrode being a counter electrode, a reference electrode or a counter/reference electrode. The working electrode and the interferent electrode each have a layer of a conductive material. The working electrode has an enzyme whereas the interferent electrode is devoid of enzyme. A method for producing the fully or partially implantable analyte sensor for continuously monitoring analyte concentration in a body fluid is also disclosed.

Diabetes analysis system for analysis and interpretation of data related to glucose level (GL) in blood. The system includes an input module to receive GL related data from measurements of interstitial fluid in subcutaneous tissue, and a hypoglycemia identification module to identify hypoglycemic events by performing a computer-implemented automatic search of the received GL related data. All uninterrupted glucose levels less than a predetermined level in a same time series are considered as one hypoglycemic event. A hypoglycemia classification module analyzes, for each identified event, the glucose data during a predetermined first time period preceding the hypoglycemic event, to determine the glucose level during the first time period. The hypoglycemia classification module determines the type of hypoglycemia event, based upon the glucose level during the first time period, by applying a computer-implemented pattern search procedure on a predetermined hypoglycemic classification scheme, in order to identify the underlying cause of hypoglycemia.

The present invention is directed to the production of stretchable wrinkled film electrodes for use in wearable/portable ROC systems using electrochemical analysis techniques. A polymer layer is disposed on a conductive substrate and a sacrificial layer is disposed on said polymer layer. An electrode shape template is cut out of adhesive and disposed on the sacrificial layer. A metallic film is disposed on the sacrificial layer by the electrode shape template. The disposed layers are removed from the conductive substrate and placed in an oven to allow said layers to shrink. The shrunken metallic film is treated with a solution to promote bonding between the film and an elastomer. The elastomer is drop-cast onto the shrunken film and the sacrificial layer is dissolved to detach the shrunken polymer layer. The shrunken film and elastomer are placed in a chemical bath and dried, producing the stretchable wrinkled film electrode.

A method for evaluating a biological effect of far infrared (FIR) includes the following. An FIR radiation source is provided to emit FIR. An FIR biological effect index (FBI) of the FIR is measured. A ratio of a blood glucose level change of an experimental group irradiated with the FIR to a blood glucose level change of a control group not irradiated with FIR is defined as the FBI. When the FBI is greater than 1, it is evaluated that the FIR causes a biological effect on an organism.

A method of testing one or more analyte sensors each comprising a first electrode; a second electrode; and a material layer disposed on or above the first electrode; the method including (a) applying a voltage potential to the first electrode with respect to the second electrode; (b) measuring a test signal comprising an output current from the first electrode that results from the application of the voltage potential; (c) using the test signal from (b) to observe an electrical characteristic of the analyte sensor; and (d) correlating the electrical characteristic a parameter associated with an electrochemical response of the analyte sensor to an analyte, wherein the testing is under dry conditions without exposure of the electrodes to a fluid containing the analyte or an in-vivo environment containing the analyte.

Systems and methods are provided for non-invasive measurement of endogenous S-nitrosothiols and related measurements thereof. One or more sensors non-invasively measures a set of one or more biometric parameters within a region of interest of a subject to provide a time series of measurements for each of the set of biometric parameters. A medium stores machine-readable instructions that are executable by an associated processor to perform processing comprising receiving the time series of measurements of the biometric parameter, generating, using a predictive model, a value representing an endogenous S-nitrosothiol content of tissue within the region of interest from the time series of measurements of the biometric parameter, and providing, by a user interface, the value representing the endogenous S-nitrosothiol content of tissue within the region of interest to a user.