The present disclosure provides a method and system for estimating the clinical responsiveness of a patient to a dose of a plasminogen activating agent to treat a thrombosis, comprising determining a concentration of α2-antiplasmin in a blood sample of the patient, determining a concentration of activated fibrinolysis inhibitor (“TAFI”) in the blood sample, determining a concentration of plasminogen activator Inhibitor 1 (“PAI-1”) in the blood sample, computing a clot lysis time (“CLT”) based on the concentrations of a2-antiplasmin, TAFI and PAI-1 using the equation CLT=−2,813.6+31.1*a2-antiplasmin (percent activity)+31.1*TAFI (percent activity)+1.49 PAI-1 (ug/L), and determining that the patient is at increased risk of hemorrhage when the computed CLT is less than a first predetermined cutoff time.

A technology for a wearable medical device for monitoring medical parameters. Medical measurement data can be received at the wearable medical device from a medical measurement sensor attached to the wearable medical device or a medical measurement sensor in communication with the wearable medical device. A calibration coefficient can be determined for calibrating the wearable medical device based on the medical measurement data. The wearable medical device can be calibrated based on the calibration coefficient.

an object information acquiring apparatus comprises a light emission unit configured to emit light beams from a plurality of emission positions; a conversion unit configured to convert acoustic waves generated when an object is irradiated with the light beams emitted by the light emission unit into electric signals; a beam profile acquisition unit configured to acquire information relating to beam profiles of the light beams emitted by the light emission unit, the beam profiles corresponding respectively to the plurality of emission positions; and a characteristic information acquisition unit configured to acquire characteristic information of the object on the basis of the information relating to the beam profiles corresponding to the plurality of emission positions and the electric signals.

A mobile device, methods and systems provide the invention mobile Personal Health Records (PHR) management platform solution. The platform enables secure PHR data management, measuring user's medical parameters, managing PHR secured depository containing user's health data on the user's invention combined phone & add-on sleeve device, while blocking none legitimate users access to the invention devices secured storage content. The invention device user's authentication is based on the combined weighted fusion of at least two different human biological sensors within the device and their weighted output analysis. The multi-sensors ensure bio-authentication secured memory entry only for the legitimate device user. In case of authentication success it activates various types of applications on the user PHR data depository content stored in device. The system supports the user's PHR remote health management, remotely monitoring the user's measured medical parameters, updating & managing user's health medical history depository in the user's electronic sleeve.

In the present invention, a system and associated method is provided for monitoring vital parameters of a patient. The monitoring system includes sensors disposed on the patient and operably connected to a monitor. The parameters that are sensed by the sensors are transmitted to the monitor and compared with alarm thresholds stored within the monitor. The alarm thresholds stored within the monitor are modified by inputs supplied to the monitor regarding the particular condition(s) of the patient being monitored to provide more accurate alarm determinations for the patient. The dynamic adjustment of the alarm threshold during monitoring can be based on a set of proactive inputs to prevent and/or limit the occurrence of unnecessary or clinically irrelevant alarm conditions or a set of reactive inputs that follow immediately after an alarm event is detected, to enable medical personnel to appropriately respond to sensed alarm condition(s).

Systems and methods are provided for optimizing hemodynamics within a patient's heart, e.g., to improve the patient's exercise capacity. In one embodiment, a system is configured to be implanted in a patient's body to monitor and/or treat the patient that includes at least one sensor configured to provide sensor data that corresponds to a blood pressure within or near the patient's heart; at least one component designed to cause dyssynchrony of the right ventricle, and a controller configured for adjusting the function of the at least one component based at least in part on sensor data from the at least one sensor.

A method of analysis using mass spectrometry and/or ion mobility spectrometry is disclosed comprising: (a) using a first device to generate smoke, aerosol or vapour from a target in vitro or ex vivo cell population; (b) mass analysing and/or ion mobility analysing said smoke, aerosol or vapour, or ions derived therefrom, in order to obtain spectrometric data; and (c) analysing said spectrometric data in order to identify and/or characterise said target cell population or one or more cells and/or compounds present in said target cell population.

A wearable respiration monitoring system having a transmitter coil that is adapted to generate and transmit multi-frequency AC magnetic fields, two receiver coils adapted to detect variable strengths in two of the AC magnetic fields and generate AC magnetic field strength signals representing anatomical displacements of a monitored subject, and at least one accelerometer that is configured to detect and monitor anatomical positions and movement of the subject, and generate and transmit accelerometer signals representing same. The wearable monitoring system further includes an electronics module that is adapted to receive the AC magnetic field strength signals and accelerometer signals, and determine at least one respiratory disorder as a function of the AC magnetic field strength signals and at least one anatomical position of the subject as a function of the accelerometer signals.

There is described a method and system for measuring a level of anxiety. Measured data comprising EEG data collected from a parietal (P) EEG electrode is received. A group 8 indicator based on a power, P-power (dt), associated with a delta-theta frequency band, dt, within a delta-theta frequency range is extracted. Based on said group 8 indicator, a level of anxiety, LoA, is determined which is a value indicative of the level of anxiety of the subject.

A detection device for detecting and characterizing biological energy fields emitted by biological specimens is configured to collect and analyze an electromagnetic signal that includes millimeter-length waves generated by the interaction of atmospheric plasma with torsion waves of the biological energy field. The device performs spectral analysis on the millimeter waves to determine characteristics of the corresponding torsion waves that generated them. An array of several hundred non-thermal plasma plumes are placed directly in front of a circular horn. A switchable circular polarizer is used to select left hand circular, linear or right hand circular polarization. A low noise frequency converter allows a noise temperature of less than 1150 K. A frequency scan and averaging algorithm is developed to characterize noise temperature versus frequency, comparing signal and noise levels between plasma on and plasma off, and switching polarization sense.