The invention relates to a fluid analysis module that comprises for blood analysis: a module housing with a fluid inlet port; at least one fluid sensor that is integrated within the module housing and comprises a sensor surface that is able to make a fluidic connection with the fluid inlet port; a chamber integrated within the module housing. The chamber can be brought into a fluidic connection with the sensor surface of the at least one fluid sensor. At least one first liquid reservoir attached within the chamber which is able to be brought into a fluidic connection with the sensor surface of the at least one fluid sensor; and at least one module housing surface, on which an elastic, fluid-tight separating wall that is embodied in membrane-like fashion is attached At least in portions, under a separating wall at least one fluidic functional configured as a flow valve and at least one fluidic functional element configured as a delivery pump is attached so that the fluidic functional elements are operable by local mechanical deformation of the separating wall: a) only deliver fluid from the fluid inlet port into the chamber via the sensor surface and b) only deliver a liquid housed in the liquid reservoir from the liquid reservoir into the chamber via the sensor surface.

Methods, systems, and apparatus, including biological fluid monitoring systems comprising a microneedle layer; at least one electromagnet assembly; and at least two liquid chambers coupled via a microfluidic layer, wherein the microneedle layer comprises a plurality of microneedles configured to extract interstitial fluid (ISF) from a patient in to one of the at least two liquid chambers, and wherein the at least one electromagnet assembly is configured to a move a test sample of the extracted ISF through the at least two liquid chambers to conduct a test cycle.

In one aspect, a dermal patch is disclosed, which comprises at least one needle configured for puncturing a subject's skin so as to allow drawing blood from the subject, a first blood-transfer fluidic channel for receiving at least a portion of the drawn blood, and a serum-separation element fluidly coupled to said first blood-transfer fluidic channel for receiving at least a portion of the drawn blood and separating a serum component thereof. In some embodiments, the dermal patch may include at least one reservoir for storing blood-processing reagent(s).

This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow real-time detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications.

A method of measuring body fluid content, the method comprising computer executed steps, the steps comprising: receiving a value of a temperature of a body part of a subject, and generating corrective data based on the received measured temperature value and on previously gathered data, the corrective data being usable for correcting a measurement of content of a fluid sample taken from the body part.

The present disclosure generally relates to receiving bodily fluid through a device opening. In one aspect, the device includes an interface that facilitates piercing of skin and/or withdrawal of fluid from the skin. The skin may be subjected to vacuum from a vacuum source.

A vacuum pad may include a top layer forming a top surface of the vacuum pad; a bottom layer forming a bottom surface of the vacuum pad; and a plurality of spacers located between the top layer and the bottom layer such that an interior space is formed between the top layer and the bottom layer. The interior space may have at least one channel extending around at least one spacer of the plurality of spacers. The vacuum pad may also include an outlet tube in fluid communication with the interior space, where the top layer includes a plurality of holes. A vacuum system may include the vacuum pad along with a canister and a vacuum source for moving fluid from the vacuum pad to the canister.

Methods and systems for determining the concentration of one or more analytes from a sample such as blood or plasma are described. The systems described herein can be configured to withdraw a certain volume of sample from a source of bodily fluid, direct a first portion of the withdrawn sample to an analyte monitoring system and return a second portion of the sample to the patient. The analyte monitoring system can include an automated blood withdrawal system that is configured to withdraw blood from the patient's vasculature at low pressure and/or withdrawal rates so as to reduce or prevent contamination of the withdrawn fluid from the infusion fluids.

A sampling apparatus can have an elongate tube and a liquid partitioning unit, first port can receive an incoming flow of test liquid and a second port may be coupled to the elongate tube. The liquid partitioning unit can combine the flow of test liquid with a plurality of partitioning elements to define a plurality of discrete liquid samples for movement along and storage in the elongate tube.

A fluid control device includes an inlet configured to be placed in fluid communication with a bodily fluid source and an outlet configured to be placed in fluid communication with a fluid collection device. The fluid control device has sequestration portion that can be vented or evacuated. The fluid control device has a first state in which an initial volume of bodily fluid can flow from the inlet to the sequestration portion and a second state in which (1) the initial volume is sequestered in the sequestration portion, and (2) a subsequent volume of bodily fluid, being substantially free of contaminants, can flow through at least a portion of the fluid control device and into the fluid collection device. The fluid control device can transition automatically or in response to an actuation of a portion of the fluid control device after the sequestration portion receives the initial volume.