A hand-held applicator (10) for collecting, mixing, diluting and discharging a sample liquid, comprising a main body (20) having an inlet-aperture (24), an outlet-aperture (26) and a chamber (22) for storing a liquid solution, wherein the chamber is connected to the inlet-aperture and the outlet-aperture, a lid (12) for covering the inlet-aperture and a tube (40), moveably supported in the inlet-aperture when the lid is covering the upper portion of the main body, wherein the tube (40) is moveable between a predetermined position outside the chamber and a position, in which the tube is at least partly located in the chamber.

A blood-viscosity measurement blood collection tube includes a bottomed tube provided with an opening at one end in a length direction and a bottom at the other in the length direction, and a sealing plug. The sealing plug includes a sealing part fitted in the opening of the bottomed tube in a hermetically sealed state, a cap part, and a thin connecting part. The sealing part includes a vertically penetrated insertion hole. The sealing part of the sealing plug is fitted in the opening of the bottomed tube, and an inner space of the bottomed tube is in a negative pressure state. The cap part is configured to be removed from the sealing plug by breaking the connecting part with an external force applied to the cap part, and the insertion hole is exposed at an upper surface of the sealing part when the cap part has been removed.

A syringe for obtaining a target volume of blood is presented. The syringe (1) comprises a barrel (2), wherein a plunger (4) is arranged within the barrel (2) to be displaceable along a displacement direction (X). Furthermore the barrel (2) and the plunger (4) together provide for a first stop (20) and second stop (22), wherein the first stop (20) is configured for positioning a filter (100) at a predetermined location along the displacement direction (X) thereby defining a target volume of blood and a buffer volume. Moreover, the second stop (22) is configured to stop the plunger (4) from expelling more than the buffer volume from the syringe (1) for obtaining the target volume of blood when the plunger (4) is pushed towards the distal end (30) of the syringe (1) along the displacement direction (X). In addition, the syringe (1) facilitates that the syringe (1) fills itself with the target volume of blood by a self-filling procedure using blood that is under pressure, like arterial blood, and using the filter (100) located in the plunger (4).

A secure specimen sample bottle includes a base container for receiving a specimen. The base container has a plurality of locking protrusions formed along an inner surface of the base receptacle. A bottle includes a lock ring that has an upright spire structure that has a closed top end and the opposing open bottom end including a plurality of flexible fins that are configured to interlockingly mate with the locking protrusions so as to prevent removal of the lock ring relative to the base container upon engagement of the flexible fins to the locking protrusions. A removable cap is coupled to the lock ring.

A biological fluid collection system that receives a sample and provides flow-through blood stabilization technology and a precise sample dispensing function for point-of-care and near patient testing applications is disclosed. A biological fluid collection system of the present disclosure is able to effectuate distributed mixing of a sample stabilizer within a blood sample and dispense the stabilized sample in a controlled manner. In this manner, a biological fluid collection system of the present disclosure enables blood micro-sample management, e.g., passive mixing with a sample stabilizer and controlled dispensing, for point-of-care and near patient testing applications.

A blood collection tube for physically separating the plasma and red blood cell fractions of a centrifuged sample is described. The blood collection tube has an elastomeric sleeve with rigid tube segments at both ends. Following blood collection and centrifugation, the elastomeric sleeve may be twisted to constrict its inner diameter and physically separate the two fractions. The blood collection tube may be secured in this position with a pin and a clamp, and further with an adhesive tape with pH paper. This enables blood samples to be transferred over long distances to a central lab facility without spoiling.

A cap and seal system for a liquid medicament container. The system comprises a cap formed from a substantially rigid material, and has a retention component integrally formed therewith. A seal is formed from a material which is less hard than the cap and positioned within the cap such that, when the retaining component retains the cap on a container in use the seal is positioned such that it forms a fluid tight seal between the cap and the container. A recess is formed in the seal through which a liquid outlet channel can pass in use to access the contents of the container via the cap and the seal.

An apparatus includes a transfer adapter, a puncture member, a disinfection member, and a fluid reservoir. The transfer adapter has a proximal end portion and a distal end portion, and defines an inner volume configured to receive the puncture member. The transfer adapter is coupled to the disinfection member. The distal end portion of the transfer adapter includes a port fluidically coupled to the puncture member and configured to be placed in fluid communication with a bodily-fluid of a patient. The proximal end portion is configured to receive a portion of the fluid reservoir to allow the fluid reservoir to be moved within the inner volume between a first position, in which a surface of the fluid reservoir is placed in contact with the disinfection member, and a second position, in which the puncture member punctures the surface to place the puncture member in fluid communication with the fluid reservoir.

The invention provides devices that improve tests for detecting specific cellular, viral, and molecular targets in clinical, industrial, or environmental samples. The invention permits efficient detection of individual microscopic targets at low magnification for highly sensitive testing. The invention does not require washing steps and thus allows sensitive and specific detection while simplifying manual operation and lowering costs and complexity in automated operation. In short, the invention provides devices that can deliver rapid, accurate, and quantitative, easy-to-use, and cost-effective tests.

Methods and devices are provided for sample collection. In one example, a device is provided comprising at least one capillary tube or collection channel directed to a sample vessel, wherein in a one-step removal step of detaching the sample vessel from the collection channel, a vacuum force is created within the sample vessel, due in part of the pulling of the sealed vessel away from the device, wherein this vacuum force draw out residual sample that may still be resident in the collection channel.