Temperature sensors are configured to sense a temperature for the sleeper and transmit temperature readings. A controller is configured to receive temperature readings; and send to a heating subsystem instructions to initiate a warming process that raises a distal temperature of the sleeper more than a proximal temperature of the sleeper. The heating subsystem that may include a heating element that, when engaged, can raise the distal temperature of the sleeper more than the proximal temperature of the sleeper.

A system includes a memory storing a user profile for a user of the system and machine-readable instructions and a control system including one or more processors configured to execute the machine-readable instructions to receive physiological data associated with the user during a sleep session, determine, based at least in part on the received physiological data, a set of sleep-related parameters for the sleep session, subsequent to the sleep session, select one of the set of sleep-related parameters as a targeted parameter, the selection of the targeted parameter being based at least in part on the stored user profile, the set of sleep-related parameters, or both, and cause information to be communicated to the user via a user device, the information being indicative of the targeted parameter, a recommendation associated with improving the targeted parameter for the user in one or more subsequent sleep sessions, or both.

Patient sleep is staged using personalized circadian models built with data collected by wearable devices over daytime and nighttime hours, thus capturing a patient's personal circadian rhythms. The circadian model is used to identify sleep intervals in incoming nightly data for the patient. The identified sleep intervals are analyzed by the machine learning system which stages epochs of sleep. Methods include receiving patient heart rate data from over a plurality of circadian cycles; creating a circadian model for the patient with a defined operation for applying sleep labels to new data from the wearable device; applying the circadian model to nightly test data from the device to identify a sleep interval; and assigning, with a classifier, sleep stages to epochs of the sleep interval.

A method includes receiving physiological data associated with a user during a sleep session. The method also includes determining a sleep-wake signal for the user during the sleep session based at least in part on the received physiological data. The method also includes determining one or more sleep-related parameters for the user during the sleep session based at least in part on the sleep-wake signal. The method also includes determining that the user experienced insomnia during the sleep session based at least in part on at least one of the one or more sleep-related parameters. The method also includes identifying a type for the insomnia experienced by the user based at least in part on the one or more sleep-related parameters.

An electronic device according to an embodiment includes a speaker capable of outputting a sound wave, a sensor capable of acquiring an optical signal related to blood flow at a measured part of a user, and a controller configured to measure blood flow information of the measured part based on the optical signal. The controller estimates a sleep state of the user based on the blood flow information and controls, based on the sleep state, a sound wave outputted from the speaker.

A smart ring includes a battery, memory, processing circuitry, a plurality of sensors, a plurality of antennas, and a battery, each coupled to one another and all enclosed in a casing, wherein the processing circuitry is configured to conserve the battery by any of sending data to the cloud service when an application is open on the user device, sending data to the cloud service when a threshold is crossed, waking up processing or communicating when there is a change in motion detected by the accelerometer.

The present disclosure provides a pharmaceutical composition for multi-stage release of psychoactive substances including cannabinoids. The pharmaceutical composition comprises two or more staged compositions having different release profiles or different release time such that the one or more active agents in each of the two or more staged compositions are released into the subject's blood stream at different time points.

Disclosed are devices and methods for estimating blood pressure, which implement a pulse-transit-time-based blood pressure model that can be calibrated. Some implementations provide reliable and user friendly means for calibrating the blood pressure model using blood pressure perturbation methods and multiple sensors.

A dynamic wake-up alarm is provided-for, including a clock, a contactless biometric sensor, a processor, memory, and a speaker. The processor may be configured to receive a wake-up rule based on at least two wake-up criteria including a time from the clock and data from the biometric sensor, and evaluate whether the criteria are met to activate an alarm.

The present invention relates to methods for modulating bursts of oscillatory brain activity, such as sleep spindles, in a subject. The invention further relates to methods of improving memory or cognitive function in a subject and method of modulating or enhancing the frequency of occurrence, structure, amplitude, and/or synchronization of sleep spindles in a subject by detecting a burst of oscillatory brain activity in the subject and passing an oscillating current through the skull of the subject.