Provided are a method and ultrasound diagnosis apparatus for measuring and displaying an elasticity of an object. The ultrasound diagnosis apparatus includes: a processor configured to obtain elasticity data of a measurement target region of an object, calculate elasticity values of a plurality of regions included in the measurement target region based on the elasticity data by using different calculating methods, and combine the calculated elasticity values of the plurality of regions to calculate a final elasticity value; and a display configured to display the final elasticity value.

Systems and methods for harmonic shear wave detection using low frame rate ultrasound, or a three-dimensional (3D) volumetric scan, are provided. As one example, spurious motion sources, such as intrinsic tissue motion and waves that are not at the incident wave harmonic frequency, are removed based on a scanning sequence in which repeated acquisitions from a given subvolume occur closely in time so as to render effects of the spurious motions negligible. As another example, sampling frequency and center frequency are selected such that the spurious motion signal spectra do not overlap with aliased shear wave motion spectra, such that the spurious motions can be filtered.

An apparatus comprising an array of polymer-based capacitive micromachined ultrasonic transducers positioned on a substrate. The substrate may be at least substantially transparent to ionizing radiation, be flexible, and/or have walls positioned thereon to protect the transducers.

Methods and devices for producing cavitation in tissue are provided. Methods and devices are also provided for surgical navigation, including defining a target treatment zone and navigating a focus of a therapy transducer to the target treatment zone. Embodiments are provided for co-registering a plurality of surgical imaging and navigation systems. Systems for performing Histotripsy therapy are also discussed.

Disclosed are an elasticity imaging method, a system and a storage medium. The method comprises: controlling an ultrasonic probe to transmit first ultrasound waves to a target object to generate shear waves propagating in a region of interest of the target object; controlling the ultrasonic probe to transmit second ultrasonic waves to the ROI to track the shear waves propagating in the ROI and receive echoes of the second ultrasonic waves, and acquiring second ultrasonic echo data based on the echoes of the second ultrasonic waves; generating a shear wave elasticity image and a strain elasticity image based on the second ultrasonic echo data; and displaying the shear wave elasticity image and the strain elasticity image. As such, the strain elasticity data is calculated according to the shear wave detection data, to enable the combination of shear wave elasticity imaging and strain elasticity imaging.

The invention relates to an ultrasonic method for estimating a nonlinear shear wave elasticity of a medium, the method comprising the following steps: A1. a first collection step in which a first set comprising one shear wave elasticity data point of the medium is collected at a first level of deformation applied to the medium, A2. a second collection step in which a second set comprising one shear wave elasticity data point of the medium is collected at a second level of deformation applied to the medium different to the first level, A3. a deformation estimation step in which the difference of deformation between the first and the second level of deformation is estimated, B1. a calculation step in which a gradient between at least two data points respectively belonging to the first and the second set is calculated as a function of the difference of deformation between the first and the second level of deformation, B2. an elasticity estimation step in which the nonlinear shear wave elasticity of the medium is estimated as a function of the gradient.

An ultrasound imaging device includes: a first transmitter configured to transmit a transmission signal to at least one piezoelectric element; a receiver configured to receive a reception signal from the at least one piezoelectric element; a second transmitter configured to transmit a given signal to the at least one piezoelectric element; a timing controller configured to control a transmitting timing at which the first transmitter transmits the transmission signal and a receiving timing at which the receiver receives the reception signal; and a signal controller configured to cause the second transmitter to transmit the given signal to a first area to which the first transmitter does not transmit the transmission signal at the transmitting timing or cause the second transmitter to transmit the given signal to a second area from which the receiver does not receive the reception signal at the receiving timing.

Disclosed are a system and a method for ultrasound elastography and a method for dynamically processing frames in real time. The system includes an elasticity processing apparatus having an elasticity information detecting module for extracting elasticity information representing the elasticity of a target to be detected; a quality parameter calculating module for calculating at least a quality parameter reflecting quality of each elasticity image corresponding to the elasticity information; and a frame processing module for determining whether to output corresponding elasticity image based on the quality parameter of each elasticity image. When calculating a strain of consecutive images, the parameter reflecting the quality of each image is also computed, through which, the current elasticity image is determined whether to be displayed, thus avoiding the situation that colors of acquired successive elasticity images may vary greatly due to large difference existing in stress.

Ultrasound-based estimation of disease activity, such as for NAS or other activity index for NAFLD for liver disease, is provided. Ultrasound measures acoustic scatter and shear wave propagation parameters, such as measuring acoustic backscatter coefficient, shear wave velocity, and shear wave damping ratio. A score for the disease activity is determined from these scatter and shear wave propagation parameters. The physician may be assisted by relatively inexpensive and rapid ultrasound as compared to biopsy or MRI based scoring in scoring activity of a disease, such as NAFLD. Ultrasound imaging is more readily available and less expensive and MRI, and is non-invasive.

An analysis apparatus includes processing circuitry configured to obtain quantitative values of a plurality of types of tissue properties relating to a region of interest of a subject, and generate a diagram of the region of interest based on the quantitative values.