A target biopsy system employing an ultrasound probe (20), a target biopsy needle (30) and a ultrasound guide controller (44). In operation, the ultrasound probe (20) projects an ultrasound plane intersecting an anatomical region (e.g. a liver). The target biopsy needle (30) include two or more ultrasound receivers (31) for sensing the ultrasound plane as the target biopsy needle (30) is inserted into the anatomical region. In response to the ultrasound receiver(s) (31) sensing the ultrasound plane, the ultrasound guide controller (44) predicts a biopsy trajectory of the target biopsy needle (30) within the anatomical region relative to the ultrasound plane. The prediction indicates the biopsy trajectory is either within the ultrasound plane (i.e., an in-plane biopsy trajectory) or outside of the ultrasound plane (i.e., an out-of-plane biopsy trajectory).

A fixture for securing a sonography transducer in place against a test surface of a phantom has a cap having a cap surface, wherein the cap is formed to seat against an edge of the phantom and to maintain spacing between the cap surface and the test surface. One or more cutouts in the cap surface are dimensioned to accept the sonography transducer. One or more flexible supports within or adjacent the one or more cutouts are configured to stabilize at least one side of the transducer within the cutout.

Apparatus for calibration includes a mount and one or more acoustic targets. The mount, which is adapted to hold a medical probe, includes an acoustic imaging device that emits ultrasonic beam in a plane, while permitting an orientation of the plane of the ultrasonic beam to be adjusted. The one or more acoustic targets are arranged to continuously intersect the plane of the ultrasonic beam over a given range of orientation angles.

The disclosure herein relates to systems, methods, and devices for medical image analysis, diagnosis, risk stratification, decision making and/or disease tracking. In some embodiments, the systems, devices, and methods described herein are configured to analyze non-invasive medical images of a subject to automatically and/or dynamically identify one or more features, such as plaque and vessels, and/or derive one or more quantified plaque parameters, such as radiodensity, radiodensity composition, volume, radiodensity heterogeneity, geometry, location, and/or the like. In some embodiments, the systems, devices, and methods described herein are further configured to generate one or more assessments of plaque-based diseases from raw medical images using one or more of the identified features and/or quantified parameters.

To uniformly extract a secondary flow based on quantitative calculation even in a complicated blood flow in a heart chamber or a blood vessel. There is provided a secondary flow detection device, including: a degree-of-swirl map calculation unit that obtains a velocity vector map calculated based on an echo signal reflected by an inspection target, calculates, as a value indicating a degree of a spatial change of a velocity vector, a degree of swirl based on the velocity vector map, and calculates, as a degree-of-swirl map, a spatial distribution of an iso-degree-of-swirl line obtained by connecting the degree of swirl of an equal value; a secondary flow candidate extraction unit that extracts, as a secondary flow candidate, an iso-degree-of-swirl line satisfying a predetermined condition among the iso-degree-of-swirl line indicated in the degree-of-swirl map; a feature amount calculation unit that calculates a feature amount of the velocity vector inside the secondary flow candidate; a secondary flow determination unit that determines whether the secondary flow candidate is a desired secondary flow based on the feature amount; and a secondary flow extraction unit that extracts and outputs the secondary flow determined by the secondary flow determination unit.

A multi-modality phantom is provided. The multi-modality phantom includes a container and an insert. The container defines an exterior that is separated from an interior space and designed to receive a tissue-mimicking medium for an ultrasound imaging process. The container further includes at least one access port formed in the container to perform the ultrasound imaging process of the interior space. The insert can be dimensioned to be selectively arranged within the interior space of the container. The insert includes imaging features arranged to simulate an environment and constructed to yield simultaneous imaging results when performing the ultrasound imaging process and at least one non-ultrasound imaging process.

A method of non-destructive evaluation of mechanical properties of a material using ultrasonic waves in a monostatic configuration is disclosed. The method comprises remotely scanning a sample of the material without directly contacting the sample, measuring an acoustic impedance of the scanned sample, and calculating mechanical properties of the material using the acoustic impedance.

Provided is a simulation phantom including a simulated target volume and a simulated normal tissue encasing the simulated target volume, wherein the simulated target volume and a portion of the simulated normal tissue abutting the simulated target volume have a first characteristic to enable the simulation phantom to be imaged on a first imaging device, and the simulated target volume and the portion of the simulated normal tissue abutting the simulated target volume further have a second characteristic to enable the simulation phantom to be imaged on a second imaging device different from the first imaging device.

A photoacoustic tomography system includes a first ring-shaped mirror having a central axis therethrough and configured to converge light inwardly towards the central axis and a subject, and an adjustment mechanism configured to move the first ring-shaped mirror along the central axis to a plurality of different positions. Each position of the plurality of different positions allows the first ring-shaped mirror to illuminate a respective ring of light around a respective portion of the subject, and an acoustic signal detector is movable along the central axis such that acoustic signals can be detected from the respective portion of the subject when illuminated by the first ring-shaped mirror while at each respective position of the plurality of different positions.

The wave number and phase velocity (shear wave speed) of ultrasound energy within an organ of interest are calculated using a herein-disclosed phase gradient calculation method. This calculation method is less sensitive to imperfections in the reverberant field distribution and requires a smaller support window, relative to earlier calculation methods based on autocorrelation. Applications are shown in simulations, phantoms, and in vivo liver.