The embodiments of the present invention provide a system and method for light and shadow guided needle positioning. DICOM images of a patient are captured for identifying a point of insertion of a needle on the patient's body and a target point inside the patient's body. Needle coordinates are computed based on the captured DICOM images to position the mechanical arms. Light is projected at a particular angle on the needle to form shadows of the needle. Laser light beams are projected to form cross hair at the point of insertion. Images or videos of the point of insertion, shadow of the needle and the cross hair are captured and displayed on a monitoring unit. A virtual circle is projected on the displayed image and is aligned with the point of insertion, shadow of the needle and cross hair in order to insert the needle precisely.

The embodiments of the present invention provide a system and method for light and shadow guided needle positioning. DICOM images of a patient are captured for identifying a point of insertion of a needle on the patient's body and a target point inside the patient's body. Needle coordinates are computed based on the captured DICOM images to position the mechanical arms. Light is projected at a particular angle on the needle to form shadows of the needle. Laser light beams are projected to form cross hair at the point of insertion. Images or videos of the point of insertion, shadow of the needle and the cross hair are captured and displayed on a monitoring unit. A virtual circle is projected on the displayed image and is aligned with the point of insertion, shadow of the needle and cross hair in order to insert the needle precisely.

A surgical device comprising an elongated body, a tissue penetrating apparatus and a light projector. The elongated body can reach with distal end thereof a surface of an organ within a subject's body. The tissue penetrating apparatus can be extended from the elongated body distal end along a curved penetration path restricted to a chosen penetration plane. The light projector can generate a shaped illumination on the surface of the organ indicative of an intersection of the penetration plane with the surface of the organ.

Various embodiments of a surgical instrument are disclosed. The surgical instrument includes a handle, a working element extending from the handle configured to be positioned internal of a target site while the handle is external to the target site, and a laser guide configured to generate at least one emitted marker. The emitted marker corresponds to movement of the working element internal of the target site. Various embodiments of methods using the surgical instrument are also disclosed.

Various embodiments of a surgical instrument are disclosed. The surgical instrument includes a handle, a working element extending from the handle configured to be positioned internal of a target site while the handle is external to the target site, and a laser guide configured to generate at least one emitted marker. The emitted marker corresponds to movement of the working element internal of the target site. Various embodiments of methods using the surgical instrument are also disclosed.

A system and method are provided for performing fluoroscopic procedures with assistance of guiding laser beam projections to reduce a reliance on harmful radiation emitting fluoroscopic imaging devices during the procedure. The system and method reduce an amount of radiation exposure to patients and medical personnel during procedures that require assistive real-time imaging. Specifically, an automated laser guidance system and method of use is provided to reduce fluoroscopic radiation, reduce operation time, and increase operative accuracy.

A method of analysis using mass spectrometry and/or ion mobility spectrometry is disclosed comprising: (a) using a first device to generate smoke, aerosol or vapour from a target in vitro or ex vivo cell population; (b) mass analysing and/or ion mobility analysing said smoke, aerosol or vapour, or ions derived therefrom, in order to obtain spectrometric data; and (c) analysing said spectrometric data in order to identify and/or characterise said target cell population or one or more cells and/or compounds present in said target cell population.

A method of analysis using mass spectrometry and/or ion mobility spectrometry is disclosed comprising: (a) using a first device to generate smoke, aerosol or vapour from a target in vitro or ex vivo cell population; (b) mass analysing and/or ion mobility analysing said smoke, aerosol or vapour, or ions derived therefrom, in order to obtain spectrometric data; and (c) analysing said spectrometric data in order to identify and/or characterise said target cell population or one or more cells and/or compounds present in said target cell population.

A medical puncture needle includes: a metal needle body formed in a tubular shape and including: a blade surface formed at a distal end portion of the needle body, a first transmission window configured to transmit light, and a second transmission window configured to transmit light transmitted through the first transmission window. The second transmission window is located on a proximal end side relative to the blade surface. The first transmission window and the second transmission window are shifted from each other in a circumferential direction of the needle body.

A robotic surgery system includes: (1) a positioning stage and (2) at least one manipulator arm mounted to the positioning stage, wherein the manipulator arm includes a track and a tool carriage moveably mounted to the track, and the tool carriage includes a base and a pair of light emitting devices mounted to the base.