The present disclosure includes apparatuses for a bone graft harvesting device. An example apparatus includes a blade tip including a proximal end and a distal end, wherein the distal end of the blade tip includes a number of blades configured to morcellate bone in response to being rotated and a lead tip located within the blade tip and configured to maintain the bone graft harvesting apparatus centered on a bone graft punch hole.

Adult autologous stem cells cultured on a porous, three-dimensional tissue scaffold-implant for bone regeneration by the use of a hyaluronan and/or dexamethasone to accelerate bone healing alone or in combination with recombinant growth factors or transfected osteogenic genes. The scaffold-implant may be machined into a custom-shaped three-dimensional cell culture system for support of cell growth, reservoir for peptides, recombinant growth factors, cytokines and antineoplastic drugs in the presence of a hyaluronan and/or dexamethasone alone or in combination with growth factors or transfected osteogenic genes, to be assembled ex vivo in a tissue incubator for implantation into bone tissue.

Disclosed is directed to a method for restoring bone in an animal comprising: accessing a site to be restored; loading a syringe body with a flowable bone graft material; mating the syringe body with a delivery tube; positioning the delivery tube at the site to be restored; using a syringe piston to advance the said material into the delivery tube; using the syringe piston or a plunger that mates with the delivery tube after removal of the syringe body to deliver the bone graft to the site at a force of less than 50 lbs. extrusion force; wherein said material is at least 75% porous with a mineral to polymer ratio of 80:20.

A milling module for converting bone stock into bone chips comprises a shell adapted for removeable attachment to a base module including a motor. The shell comprises a body, a milling element, a lid, and a locking element. The milling element for converting bone stock into bone chips is movably disposed in the shell. The lid is shaped for removeable attachment to the body to allow removal of residual bone chips from the milling element. The locking element is movable between an unlocked position wherein the locking element is positioned relative to the lid to allow removal of the lid from the body, and a locked position wherein the locking element is positioned relative to the lid to prevent removal of the lid from the body.

The device according to the invention for preparing a bone transplant (100) outside the human or animal body comprises a base element (101) and at least one holding element (102). The at least one holding element (102) is inserted in the base element (101) of the device for preparing a bone transplant (100). In the method according to the invention for configuration of the device according to the invention, the at least one holding element (102) is inserted into the base element of the device for preparing a bone transplant (100). In the method according to the invention for preparing a bone transplant outside the human or animal body with the device according to the invention (100), a bone fragment to be prepared is placed into the holding element (102) inserted in the base element (100), the bone fragment to be prepared is fixed with the inserted holding element, and the bone fragment to be prepared is processed.

A bone material dispensing apparatus for preparing, mixing, and dispensing bone material into a foldable container is provided. In some embodiments, the dispensing apparatus comprises a tray and a foldable container. The tray includes a mixing surface, a dispensing surface and a means to measure the amount of material to be dispensed. A kit including a tray, a foldable container, and a spatula are also provided. A method of using the dispensing apparatus to deliver the bone material to a bone detect is also provided.

A milling module (60) for converting bone stock into bone chips comprises a shell (34) adapted for releasable attachment to a base module (32). The shell has an inlet opening (152) through which bone stock is introduced into the shell and an outlet opening (96) through which bone chips are discharged from the shell. A milling element (170) is moveably disposed in the shell between the inlet opening and the outlet opening for converting bone stock into bone chips. The shell includes abase (62) adapted for releasable attachment to the base module. The base includes the outlet opening and a lid (126) removably attached thereto. The lid includes the inlet opening of the shell. The base and the lid are collectively configured so that removal of the lid from the base allows the milling element to be accessed.

A device for hydrating particulate bone material is provided. The device comprises a tubular member having an interior surface and an exterior surface. The interior surface is configured to receive the particulate bone material and a hydration fluid. The exterior surface has a plurality of pores configured to allow the hydration fluid to flow into the interior surface of the tubular member and hydrate the particulate bone material. The plurality of pores are smaller in size than the particulate bone material. Methods of dispensing particulate the bone material are also provided.

A bone mill includes a housing, at least a first bone milling tool, a proximal bearing sleeve, and a distal bearing sleeve. The housing defines a work chamber. The work chamber has a first axial end, a second axial end, a feed input opening, and an output opening. The bone milling tool is configured to be disposed within the work chamber, and extends at least from a first axial end to the second axial chamber. The proximal bearing sleeve is supported by the housing proximate the first axial end, and a distal bearing sleeve supported by the housing proximate the second axial end. The proximal bearing sleeve and the distal bearing sleeve support the bone milling tool and allow rotation of the bone milling tool within the work chamber about an axis.

A device for collecting bone fragments includes a housing (512) and a filter element (522) disposed in the housing. The filter element has a first end (524), a second end (526), and a sidewall (528) that defines an inner peripheral (530) and outer peripheral (532) surface and includes a plurality of filter apertures (534). The inner peripheral surface at least partially defines a collection chamber (536) for collection of a composition comprising bone fragments. The outer peripheral surface of the sidewall and the housing are spaced apart from one another to define an exterior radial volume (540). The filter element also has a proximal portion (535) adjacent the second end (526) which defines at least one drain aperture (555). The composition is acquired and collected in the collection chamber with the exterior radial volume providing a primary fluid communication path with a vacuum source and the at least one drain aperture providing a supplementary fluid communication path with the vacuum source.