The invention relates to a knit having barbs protruding outwards from both faces obtained by knitting yarns of biocompatible material in guide-bars B2, B3 and B4 of a knitting machine, wherein the knitting patterns followed by guide-bars B2 and B3 involve at least two needles and produce an arrangement of yarns defining two faces of the knit, the knitting pattern followed by guide-bar B4 making stitches generating loops protruding outwards from each of the faces of the knit, guide-bar B4 being threaded with a hot-melt monofilament yarn, heat-setting the knit, forming barbs by cutting the loops via melting.

Implantable medical constructs formed by winding using winding support structures that can be flexible and can be integrated into the medical construct with biocompatible fiber(s) and/or yarn(s) and at least one continuous length collagen fiber. The implantable medical construct can include open suture anchor apertures formed using posts during a winding sequence.

The invention relates to a prosthetic porous knit based on a monofilament of a biocompatible polymer material, the pattern followed for the knitting of said monofilament on a warp knitting machine having two guide bars B1, B2 being the following, according to the ISO 11676 standard: Bar B1: 1.2/4.5/4.3/4.5/4.3/1.0/1.2/1.0// Bar B2: 4.3/1.0/1.2/1.0/1.2/4.5/4.3/4.5// The invention further relates to a method for producing such a knit and to a hernia prosthesis comprising such a knit.

A gastroesophageal reflux preventer and related methods are provided. A gastroesophageal reflux preventer is configured to be positioned around the exterior of a body organ and may include an elongate portion including a plurality of nodes positioned along at least a portion of the length of the elongate portion.

A method and apparatus is provided for creating a modified tissue graft, wherein an anatomical site at which the modified tissue graft is to be placed is identified, desired characteristics for the modified tissue graft are identified based at least upon the anatomical site, one or more types of graft modifications and regions of the tissue graft to be modified are identified to achieve the desired characteristics; and at least a first area and a second area of the exterior surface of the tissue graft are modified by compressing, cutting and/or removing one or more portions thereof to create first designed surface features which cause the tissue graft to have first characteristics in the first area and second designed surface features which cause the tissue graft to have second characteristics in the second area.

A composite scaffold having a highly porous interior with increased surface area and void volume is surrounded by a flexible support structure that substantially maintains its three-dimensional shape under tension and provides mechanical reinforcement during repair or reconstruction of soft tissue while simultaneously facilitating regeneration of functional tissue.

The present invention relates to a prosthesis (100) comprising an openworked three-dimensional knit (101) comprising a front face and a rear face, each face being formed with one or more laps of yarns defining pores on said face, the front face being bound to the rear face by connecting yarns defining a spacer, characterized in that the connecting yarns are distributed so that they define an entanglement of yarns crossing each other at the spacer, without obstructing the pores of the front and rear faces.

The invention relates to a method for forming a mesh having a barbed suture attached thereto, comprising the following steps: a) producing a knitted structure on a knitting machine comprising at least one needle-bed with three guide bars, on a length corresponding to N stitches ranging from 1 to N, wherein i) a first knit portion is produced along stitches ranging from 1 to x, where 1<x<N, ii) a second knit portion is produced for stitches ranging from (x+1) to N, in which the knitting pattern produces at least one weft stitched chain stitch, b) cutting the second knit portion on both sides of the weft stitched chain stitch and along an edge separating the second knit portion from the first knit portion, while maintaining the weft stitched chain stitch attached to the first knit portion. The invention also relates to the mesh obtained by this method.

A reinforcement device for reinforcing tissues having one or more structural deficiencies includes a longitudinally-extending reinforcing layer for treating the structural deficiency, a plurality of spiked naps distributed across the reinforcing layer and projecting therefrom for adhering to the tissue, and a dissolvable matrix layer covering at least a portion of the reinforcing layer and a portion of the plurality of spiked naps. The matrix layer increases the time before the spiked naps substantially adhere to the tissue, thereby allowing the practitioner additional time to position the reinforcement device.

A mesh for repair/prevention of a parastomal hernia during ostomy treatment is disclosed. More specifically, a pre-molded mesh having a unique shape to provide support to the abdominal wall adjacent a stoma formed during an ostomy procedure to prevent/repair formation of a parastomal hernia is disclosed which also provides a clearance channel through which the bowel can pass in a manner that prevents collapse or obstruction of the exposed segment of the bowel.