A transcatheter heart valve includes a paravalvular seal that is configured for transfemoral delivery. The valve includes an outer frame and the seal is formed from a plurality of outwardly extending fibers.

A stent graft configured to facilitate the placement of a secondary stent is provided and a method thereof. The stent graft can include an elongated body with a frame structure, a lumen, and apertures at both ends of the elongated body. The frame structure can be covered by a graft material. At least one station can be located in the graft material. The at least one station has a perimeter defined by a ring structure connected to the graft material and an aperture bounded by the perimeter. The aperture can be covered by graft material. The at least one station can be fenestrated to facilitate placement of a secondary stent.

The invention relates to a medical device, the medical device comprising a balloon catheter, a first stent, and a second stent; the balloon catheter having a shaft and an inflatable balloon mounted to the shaft at the distal end the balloon having a distal portion having a first outer diameter and a proximal portion having a second outer diameter, wherein the first diameter is smaller than the second diameter and a transition region located between the distal portion and the proximal portion, a first stent having a first nominal diameter mounted on the distal portion of the balloon and a second stent having a second nominal diameter mounted on the proximal portion of the balloon, a distal portion of the second stent overlapping a proximal portion of the first stent, wherein the proximal end of the first stent is positioned proximal to the distal end of the second stent, the medical device further comprising a pre-cannulation means providing a passage from the interior of the second stent to the exterior of the first stent passing the stent overlapping portion between the inner surface of the second stent and the outer surface of the first stent.

A device for treating a diseased native valve in a patient is provided, the device including a frame structure and a plurality of leaflets. The device can further include a spiral anchor configured to extend around an outer circumference of the frame structure. The anchor can be configured to deliver a contrast agent into or near a target tissue. Other embodiments and methods of use are also provided.

Some embodiments are directed to methods and systems for percutaneously treating dissections in a patient's vasculature, such as, without limitation, the aorta. The method can include deploying a catheter containing a collapsed anchoring element, frame, and cover through a first vessel to an entry point of the dissection. The anchoring element can be secured to the second branch vessel. The frame can be expanded in the first branch vessel. The cover can be unfolded over at least a portion of the entry point. The cover then reduces blood flow into the entry point.

An introduction arrangement for a fenestrated or branched stent graft (13) intended for deployment into the lumen of a vessel having a blind vessel extending from it. The introducer (1) has a distal end intended to remain outside a patient in use and a proximal end with a nose cone dilator (11) and an arrangement to retain the branched stent graft distally of the nose cone dilator. A sheath (15) on the introducer extends over the branched stent graft to the nose cone dilator. An indwelling catheter (21) extends from the distal end of the introducer and enters the fenestration or side arm and through to the nose cone dilator, the indwelling catheter has a guide wire (29) extending through it. The guide wire can be extended beyond the nose cone dilator in use before the sheath is withdrawn from the branched stent graft so that it can be snared from the contra-lateral artery.

A single access method of repairing an aneurysm in a bifurcated vascular lumen is described. A primary graft portion is configured in the bifurcated vascular lumen before a guide wire is configured through the primary graft portion and into a contralateral vessel of the bifurcated vascular lumen from the access opening. The guide wire may be a directed into the contralateral vessel and around the bifurcation in the primary graft portion by steerable sheath, a directional sleeve or a sheath having an aperture and secured to the primary graft portion by a balloon. The contralateral limb is then advanced through the access opening in the ipsilateral vessel, around the bifurcation and into the contralateral vessel.

A catheter assembly for delivery of an expandable implant having at least one branch portal, which utilizes a secondary sleeve for releasably constraining a middle portion of the expandable implant after releasing a primary constraining sleeve used for constraining the expandable implant toward a delivery configuration for endoluminal delivery; and methods of using the same.

An aortic graft assembly includes a tubular component that defines a wall aperture having a proximal end that extends perpendicular to a major longitudinal axis of the tubular aortic component, and a tunnel graft connected to the wall of the tubular aortic component and extending from the wall aperture toward a proximal end of the tubular aortic component. The aortic graft assembly is delivered to a patient through the wall aperture and into interfering relation with the tunnel graft to treat aortic aneurysms.

Medical devices and methods for placing a bifurcated stent into a bifurcating blood vessel are described herein. Also, described herein are methods for treating aorto-iliac occlusive disease. The bifurcated stent can be mounted onto a catheter comprising at least two balloons by mounting a first branch stent of the bifurcated stent onto a first balloon and a second branch stent of the bifurcated stent onto a second balloon, and a main body of the bifurcated stent onto the first balloon and second balloon.