A method and apparatus for coupling a soft tissue implant into a locking cavity formed within a bone is disclosed. A bone engaging fastener is coupled to bone. A second fastener is coupled to a suture construction. The second fastener is coupled to the first fastener. Soft tissue is coupled to the suture construction.

Expandable prosthetic devices used for treating a variety of conditions, including rotator cuff injuries, broken and/or depressed bone fractures, infection and/or inflammation in the body. In one embodiment, a prosthesis includes an implant having a pressure regulating valve. The implant is capable of being positioned between a first tissue and an opposing second tissue in a void space and of deforming under pressure in response to articulation of a joint. The pressure regulating valve is configured to open based on a predetermined pressure in the implant.

A method of reinforcing a biological construct according to an exemplary aspect of the present disclosure includes, among other things, attaching a suture loop/needle construct to a reinforcement material and stitching the reinforcement material to a biological construct to form a reinforced biological construct. The reinforcement material is attached to the suture loop/needle construct prior to approximating the reinforcement material to the biological construct.

The present disclosure relates to tissue engineering, and more particularly to a method for treating or repairing rotator cuff or other tendon tears or damage using scaffold-free 3-dimensional engineered tendon constructs.

Technologies are disclosed for an implant device that may be configured to repair tissue. The device may include a distal end configured to be connectable to at least a first part of the tissue. The device may include a proximate end configured to be connectable to at least a second part of the tissue. The device may include a substrate configured to form a connection between the first part of the tissue and the second part of the tissue. The device may include a longitudinal axis that may extend between the distal end to the proximate end within the substrate. The device may include at least one preformed channel in the substrate. The device may include at least one suture preloaded at least partially within the at least one channel. The at least one preformed channel may be formed during and/or proximate to a formation of the device.

Methods and system for the repair of a ruptured anterior cruciate ligament using a femoral attachment are provided. Aspects of the invention include a scaffold attached by a suture to an fixation device. The fixation device and suture are secured to a femur and not to a tibia near or at the repair site.

Devices and methods for reinforcing tissue grafts are described herein. In one embodiment, an implant is described that includes a proximal end portion having a through-hole formed therein, a distal end portion, and a reinforcing insert disposed in the through-hole. The insert includes a proximal face, a distal face opposed to the proximal face, a first upper surface extending between the proximal and distal faces and having a generally convex shape that abuts against at least a portion of a sidewall of the through-hole, and a second lower surface extending between the proximal and distal faces and having a generally concave shape. The second lower surface and portions of the sidewall of the through-hole not abutted by the first upper surface form a reinforced through-hole of the implant.

A bioactive scaffold for use in reconstruction of an anterior cruciate ligament of a patient, may include a tissue matrix configured to wrap around a graft configured to extend from a first bone of a joint to a second bone of the joint. The tissue matrix may include collagen type I. The tissue matrix may include a first plurality of apertures extending through the tissue matrix along a first edge of the tissue matrix and a second plurality of apertures extending through the tissue matrix along a second edge of the tissue matrix. At least one filament may be configured to be laced through the first plurality of apertures and the second plurality of apertures and draw the first edge of the tissue matrix toward the second edge of the tissue matrix when the at least one filament is subjected to tension thereby closing the tissue matrix around the graft.

A method and apparatus for coupling a soft tissue implant into a locking cavity formed within a bone is disclosed. A bone engaging fastener is coupled to bone. A second fastener is coupled to a suture construction. The second fastener is coupled to the first fastener. Soft tissue is coupled to the suture construction.

Devices and methods for reinforcing tissue grafts are described herein. In one embodiment, an implant is described that includes a proximal end portion having a through-hole formed therein, a distal end portion, and a reinforcing insert disposed in the through-hole. The insert includes a proximal face, a distal face opposed to the proximal face, a first upper surface extending between the proximal and distal faces and having a generally convex shape that abuts against at least a portion of a sidewall of the through-hole, and a second lower surface extending between the proximal and distal faces and having a generally concave shape. The second lower surface and portions of the sidewall of the through-hole not abutted by the first upper surface form a reinforced through-hole of the implant.