An anchor for anchoring tensile members to bone includes: a housing extending along a central axis, with a hollow interior; a collet in the hollow interior having a central bore for accepting tensile members and an exterior surface, the collet being configured to swage around and against tensile members; a sleeve having a peripheral wall defining interior and exterior surfaces, the sleeve disposed in the housing's hollow interior axially adjacent to the collet, and movable parallel to the central axis between first and second positions; and wherein at least one of the collet exterior surface and the sleeve interior surface is tapered and the sleeve and the collet are arranged so movement of the sleeve from the first position to the second position causes the sleeve interior surface to bear against the collet exterior surface, causing the collet to swage radially inwards around and against one or more tensile members.

Devices, systems and methods for fixating soft tissue to bone. In one embodiment, a repair device system for fixating soft tissue to bone includes a carrier member, multiple anchors, and a bone anchor. The carrier member includes multiple pad portions and a bone coupling portion. Each of the pad portions are aligned with an adjacent pad portion. The pad portions are configured to be positioned over a side of the soft tissue and the bone coupling portion is coupled to the multiple pad portions. Each anchor is sized and configured to extend through the at least one opening defined in one of the multiple pad portions and through the soft tissue. The bone anchor is configured to be coupled to the bone coupling portion and configured to be secured to the bone.

Systems and methods for fixating a graft in a bone tunnel are provided. In general, the system includes a tissue fixation device having a delivery configuration and a deployed configuration, at least one graft retention loop coupled to the tissue fixation device, and a drill pin having a sidewall surrounding a cavity at a proximal end of the pin and at least one longitudinally oriented opening in the sidewall in communication with the cavity, the cavity being configured to fully seat the tissue fixation device. The drill pin is configured to substantially contain therein the tissue fixation device when in the delivery configuration and to enable deployment of the tissue fixation device through the opening. Drill pins configured to contain a tissue fixation device are also provided.

The present invention provides compositions and methods for attaching tendon to bone. The present invention provides compositions and methods for treating rotator cuff injuries. In one embodiment, a method for treating rotator cuff injuries comprises providing a composition comprising PDGF disposed in a biocompatible matrix and applying the composition to at least one site of tendon reattachment on the humeral head.

Systems and methods for fixating a graft in a bone tunnel are provided. In general, the system includes a tissue fixation device having a delivery configuration and a deployed configuration, at least one graft retention loop coupled to the tissue fixation device, and a drill pin having a sidewall surrounding a cavity at a proximal end of the pin and at least one longitudinally oriented opening in the sidewall in communication with the cavity, the cavity being configured to fully seat the tissue fixation device. The drill pin is configured to substantially contain therein the tissue fixation device when in the delivery configuration and to enable deployment of the tissue fixation device through the opening. Drill pins configured to contain a tissue fixation device are also provided.

An adjustable fixation system for coupling a tissue or graft to bone is disclosed including a suture construct including a first limb, a second limb and a body therebetween. The body is continuously braided with the first and second limbs and has a longitudinal passage therethrough. The first and second limbs define a braided portion including a braided core. The suture construct is configured to form at least one adjustable loop formed by passing the first limb between braids of the suture construct, along the longitudinal passage and back out between braids of the adjustable suture construct. Tension on at least one of the first or second limbs reduces a diameter of the longitudinal passage around a length of the first limb and thereby the braided core disposed along the body longitudinal passage and knotlessly locks the adjustable loop.

Connective tissue-to-bone interface scaffolds (e.g., ligament-to-bone interface scaffolds, tendon-to-bone interface scaffolds, etc.). These scaffolds may be a single integrated implant or may be a modular (e.g., two-part) implant system.

Connective tissue-to-bone interface scaffolds (e.g., ligament-to-bone interface scaffolds, tendon-to-bone interface scaffolds, etc.). These scaffolds may be a single integrated implant or may be a modular (e.g., two-part) implant system.

Systems and methods for fixating a graft in a bone tunnel are provided. In general, the system includes a tissue fixation device having a delivery configuration and a deployed configuration, at least one graft retention loop coupled to the tissue fixation device, and a drill pin having a sidewall surrounding a cavity at a proximal end of the pin and at least one longitudinally oriented opening in the sidewall in communication with the cavity, the cavity being configured to fully seat the tissue fixation device. The drill pin is configured to substantially contain therein the tissue fixation device when in the delivery configuration and to enable deployment of the tissue fixation device through the opening. Drill pins configured to contain a tissue fixation device are also provided.

Connective tissue-to-bone interface scaffolds (e.g., ligament-to-bone interface scaffolds, tendon-to-bone interface scaffolds, etc.). These scaffolds may be a single integrated implant or may be a modular (e.g., two-part) implant system.