A method of modifying a refractive profile of an eye having an intraocular device implanted therein, wherein the method includes determining a corrected refractive profile for the eye based on an initial refractive profile, identifying one or more locations within the intraocular device based on the corrected refractive profile, and directing a pulsed laser beam at the locations to produce the corrected refractive profile. A system of modifying an intraocular device located within an eye, wherein the system includes a laser assembly and a controller coupled thereto. The laser assembly outputs a pulsed laser beam having a pulse width between 300 picoseconds and 10 femtoseconds. The controller directs the laser assembly to output the pulsed laser beam into the intraocular device. One or more slip zones are formed within the intraocular device in response thereto, and the slip zones are configured to modify a refractive profile of the intraocular device.

Systems and methods involving an intraocular implant with input and/or output electronics are described. In some embodiments, the system includes an intraocular lens having at least one optic operably coupled to a haptic, one or more input electronics on the haptic and/or the optic; and one or more output electronics on the haptic and/or the optic for receiving and/or transmitting data.

To provide an intraocular lens to which a mark for assisting more accurate fixation in an eye has been applied. Provided is an intraocular lens including an optical part having a mark that is detectable under illumination of a specific wavelength range outside a wavelength range of visible light, and a support part that supports the optical part, in which the mark is indicated by a geometric pattern that allows for identification of an optical center position of the optical part and information regarding posture of the optical part in an eye.

Intraocular lenses for reducing the risk of posterior capsule opacification (PCO) are described herein. PCO can be reduced with an IOL design that increases the pressure at the posterior capsular bend, for example, by including a sharper edge design, an enlarged optical zone, and/or an increased vault height. An example ophthalmic lens can include an optic (200) including an anterior surface (202) defining an anterior side of the optic, a posterior surface (204) defining a posterior side of the optic, and an edge (210) arranged between the anterior and posterior surfaces. The edge and the posterior surface can form an angle, where the angle is less than about 90 degrees. Additionally, the ophthalmic lens can have an increased vault height. At least one of the angle or the increased vault height be configured to increase pressure on a capsular bend in a subject's eye.

A light adjustable lens illumination system comprises an illumination source, for generating a light beam; a light delivery system, for projecting the light beam onto a Light Adjustable Lens (LAL), implanted into an eye, wherein a fraction of the light beam propagates past the LAL to a retina of the eye; and a protective beam-shaper, for shaping the light beam to have an intensity pattern with a relative central intensity reduction that varies along an axis; wherein the relative central intensity reduction at the retina is greater than the relative central intensity reduction at a LAL plane.

An intraocular lens is provided that includes a refractive element and a mask. The refractive element has a first power in a first meridian and a second power greater than the first power in a second meridian. A magnitude of the first and second powers and a location of the first and second meridians are configured to correct astigmatism in a human eye. The mask is configured to block a substantial portion of light from passing through an annular region thereof and to permit a substantial portion of light to pass through a central aperture thereof to enhance an astigmatism correction rotational misplacement range and depth of focus.

Exemplary light control devices and methods provide a regional variation of visual information and sampling (“V-VIS”) of an ocular field of view that improves or stabilizes vision, ameliorates a visual symptom, reduces the rate of vision loss, or reduces the progression of an ophthalmic or neurologic condition, disease, injury or disorder. The V-VIS devices and methods generate a moving aperture effect anterior to a retina that samples and delivers to the retina environmental light from an ocular field of view at a sampling rate between 50 hertz and 50 kilohertz. Certain of these V-VIS devices and methods may be combined with augmented or virtual reality, vision measurement, vision monitoring, or other therapies including, but not limited to, pharmacological, gene, retinal replacement and stem cell therapies.

A filling apparatus for filling a lens device with a volume of optical liquid including a dispensing system, a venting system having a vacuum pump and a vacuum chamber, a measurement system, and a lens device holding system. The dispensing system includes a source of optical liquid, a positive displacement pump, and a filling needle having a lumen in fluid communication with the source of optical liquid. The filling needle is configured to penetrate an injection zone of the lens device for filling an internal chamber of the lens device. The measurement system is configured to measure a lens zone of the lens device. The lens device holding system includes a lens fixture for maintaining a position of the lens device relative to the filling needle and the measurement system. Related systems, devices, and methods are provided.

An intraocular lens system comprising at least one intraocular lens having an anterior surface and a posterior surface, wherein at least one surface of the lens is aspherical to provide for a continuum of retinal images to be focused at the retina in an area between two retinal eccentricities. The system may include an anterior light-converging intraocular lens 16 for positioning within the eye, the anterior lens having an anterior surface and a posterior surface; and a posterior light-diverging intraocular lens 17 for positioning within the eye posterior to the anterior lens, the posterior lens having an anterior surface and a posterior surface; wherein one or both surfaces of the anterior lens and/or one or both surfaces of the posterior lens are aspherical.

An apparatus has a central lens body for providing vision correction for a patient. The lens body has a central aperture and is configured as one of: a diffractive lens or a refractive lens. The lens body has at least one haptic extending from the lens body, and the central aperture has a form of a circular hole extending fully through the lens body when the apparatus is implanted in the eye. The lens body is formed from a substantially transparent material and the central aperture includes a darkened perimeter. The darkened perimeter of the central aperture includes a darkened internal wall extending through the lens body from an anterior surface to a posterior surface of the lens body.