A system and method for altering bone growth on and within an orthopedic implant that includes an implant body; a plurality of electrodes, wherein each electrode is at least partially embedded in the implant body, and comprises: a set of primary electrodes comprising at least one electrode, wherein a non-embedded segment of each primary electrode is proximal to a bone growth region, a set of secondary electrodes comprising at least one electrode, wherein a non-embedded segment of each secondary electrode is distal to the bone growth region, and wherein the plurality of electrodes are configured to function in a stimulation operating mode, such that a subset of primary electrodes function as cathodes and a subset of secondary electrodes function as anodes; a control system comprising a processor, and circuitry that connects to the plurality of electrodes; and a power system.

The present invention relates to an artificial joint comprising a first joint portion (101), a second joint portion (105) and an intermediate portion (103). The first joint portion and the second joint portion each comprise an electrically conductive material and the intermediate portion comprises a non-conductive material and is arranged in between the first joint portion and the second joint portion such that the first joint portion is electrically isolated from the second joint portion. The artificial joint further comprises an internal electronic unit (110) provided inside of the isolating portion being connected to the first joint portion via at least one first electrode (111) and to the second joint portion via at least one second electrode (113). Thus, a first voltage can be applied to the first joint portion and a second electric voltage can be applied to the second joint portion, the voltages being with reference to a common reference potential.

Provided herein are biocompatible scaffolds engineered to convey growth stimulatory light to cells and augment their growth on the scaffolds both in vitro and in vivo. Also provide are methods of modifying biocompatible transparent waveguides to control delivery of light from the waveguide material.

A system and method for altering bone growth on and within an orthopedic implant comprising an implant body, wherein the implant body comprises an exterior surface and an interior surface defining an internal cavity of the implant body, a plurality of electrodes, wherein each electrode is at least partially embedded in the implant body, and comprises at least, a first set of the plurality of electrodes 116, composed of a first material, and a second set of the plurality of electrodes, composed of a second material; and a control system, comprising a processor and circuitry that connects to the plurality of electrodes, wherein the processor, through operating modes, provides machine instructions to control direction and magnitude of current traveling through each electrode from the plurality of electrodes; and a power system, comprising a power source and circuitry that provides electrical power for function of the plurality of electrodes.

An implant and/or an implant component is made available, having a main body which, at least on a surface, contains or consists of an electrically conductive material, and having a layer of calcium hydroxide applied to the electrically conductive material of the main body. The implant or the implant component is characterized in that the layer of calcium hydroxide contains calcium phosphate, specifically in a percentage by weight that is less than the percentage by weight of calcium hydroxide in this layer. A method for making available the implant according to the invention or the implant component according to the invention is also proposed. The implant made available and the implant component made available are characterized in that they have a local and temporary antimicrobial action, prevent formation of antibiotic-resistant microorganisms, act on bone substance in a manner that promotes growth, and produce no adverse side effects in the body.

An orthopedic prosthesis for stimulating bone growth may include a substrate having at least one bone-facing surface and at least one internal surface, at least one piezoelectric nanostructure coupled to the at least one bone-facing surface of the substrate, at least one charge storing material placed within the orthopedic prosthesis proximate the at least one internal surface, and an interconnect in electrical communication with the at least one piezoelectric nanostructure and the charge storing material. The at least one piezoelectric nanostructure may be configured to generate an electric charge in response to at least one mechanical force applied to the at least one piezoelectric nanostructure and the interconnect may be configured to transfer the electric charge to the at least one charge storing material to promote bone in-growth within the orthopedic prosthesis and/or on the at least one bone-facing surface.

A system and method for altering bone growth on and within an orthopedic implant comprising an implant body, wherein the implant body comprises an exterior surface and an interior surface defining an internal cavity of the implant body, a plurality of electrodes, wherein each electrode is at least partially embedded in the implant body, and comprises at least, a first set of the plurality of electrodes 116, composed of a first material, and a second set of the plurality of electrodes, composed of a second material; and a control system, comprising a processor and circuitry that connects to the plurality of electrodes, wherein the processor, through operating modes, provides machine instructions to control direction and magnitude of current traveling through each electrode from the plurality of electrodes; and a power system, comprising a power source and circuitry that provides electrical power for function of the plurality of electrodes.

A medical implant system is described for inhibiting infection associated with a joint prosthesis implant. An inventive system includes an implant body made of a biocompatible material which has a metal component disposed on an external surface of the implant body. A current is allowed to flow to the metal component, stimulating release of metal ions toxic to microbes, such as bacteria, protozoa, fungi, and viruses. One detailed system is completely surgically implantable in the patient such that no part of the system is external to the patient while the system is in use. In addition, externally controlled devices are provided which allow for modulation of implanted components.

A scaffold comprised of a plurality of PLLA layers, which may include stem cells, for regenerating bone or tissue. The PLLA layers are separated by a plurality of hydrogel layers. The PLLA layers comprise a nanofiber mesh having a piezoelectric constant to apply an electrical charge to the bone or tissue upon application of ultrasound energy.

A system and method for electrical stimulation in an orthopedic implant that includes at least one implantable component with an implant body, a plurality of electrodes, and implant circuitry is effective to convert an external wireless power transmission to an electrical current and effective to control the plurality of electrodes; and at least one non-implant with a power source, and transmitter circuitry to generate the electromagnetic field that couples with the implant circuitry.