A method of performing arthroplasty of an anatomical joint for receipt of an implant is disclosed. The method includes developing a preoperative plan, designing a patient specific guide based on the preoperative plan, obtaining the patient specific guide, placing the patient specific guide relative to the identified bone, fixing a pair of pins into the bone to establish an Alpha plane and executing the preoperative plan while referencing the Alpha plane. A desired amount of remaining first bone is determined based on a condition of the anatomical joint and a desired orientation of the implant. The patient specific guide includes a pair of bores defined therein and located in positions to accept a complementary pair of pins. The bores are arranged at locations on the patient specific guide to orient the respective pins in a direction optimized for surgeon access to the first bone and to establish the Alpha plane.

Provided herein are compositions and methods for treating bone fractures. In particular, provided herein are systems comprising carbon fiber sleeves and biocompatible polymers and the use of such systems in treating or preventing bone fractures.

A method for producing bone grafts using 3-D printing is employed using a 3-D image of a graft location to produce a 3-D model of the graft. This is printed using a 3-D printer and a printing medium that produces a porous, biocompatible, biodegradable material that is conducive to osteoinduction. For example, the printing medium may be PCL, PLLA, PGLA, or another approved biocompatible polymer. In addition such a method may be useful for cosmetic surgeries, reconstructive surgeries, and various techniques required by such procedures. Once the graft is placed, natural bone gradually replaces the graft.

Provided herein are biomimetic osteochondral implants that are generally useful for the at least partial resurfacing of damaged cartilage within a joint. The implants are constructed to have a modular, layered structure in which the physical properties (e.g., stiffness and lubricity) or dimensions of each layer can be adjusted (e.g., by using the appropriate material and controlling the thickness thereof) based on the anatomy to be replaced. For example, the material and or thicknesses of the layers can be selected to approximate the physical properties and/or dimensions of cartilage (and, optionally, chondral and subchondral bone). Also provided herein are methods of treatment involving the use of said biomimetic osteochondral implants to repair an osteochondral defect in a joint.

A medical implant for treating bone defects. The implant has at least one hollow body delimiting an inner chamber in the interior of the hollow body, a fluid feed line connected in a fluid-permeable manner with the inner chamber, and a fluid discharge line connected in a fluid-permeable manner with the inner chamber. The hollow body consists at least in places or wholly of at least one plastic material that is impermeable to liquids and permeable to oxygen and to carbon dioxide, such that oxygen is deliverable from a fluid passed through the hollow body to, and carbon dioxide is absorbable into the fluid from, the surroundings of the hollow body. Also disclosed is a bone defect treatment system having such a medical implant and the fluid, wherein the fluid contains oxygen and is suitable for absorbing oxygen, and to a method for gas-flushing a surface of a medical implant.

The present invention relates to a stem for or of an implant having a longitudinal axis and at least one recess adapted for cemented implantation into the medullary cavity and/or a cavity created by surgery of a long bone, characterized in that the recess is interrupted by a barrier. Further the present invention relates to a method for preparing a stem of an implant according to any one of the preceding claims for implantation, comprising the step of placing cement into the recess (12) on both sides of the barrier.

A system and method for improving upon an ability of a surgeon to repair traumatic bone injury using new materials, components, and structures. A structure may be used as an implant or a component of an external fixator for a fractured long bone with that structure having anisotropic and viscoelastic properties, such as through additive manufacturing techniques.

An implant assembly for a long bone having a longitudinal axis. The implant assembly has a stem that is received in a surgically prepared medullary canal of the long bone. The stem defines at least one transverse through-opening that extends through the stem from a first portion of the outer surface of the stem to an opposed second portion of the outer surface of the stem. Each transverse through-opening has a central axis that is substantially perpendicular to the longitudinal axis of the stem. Each transverse through-opening receives a fastener and has a longitudinal dimension, measured relative to the longitudinal axis of the stem, that is sufficient to permit axial movement, relative to the longitudinal axis of the stem, of the stem relative to each fastener.

A method of performing arthroplasty of an anatomical joint for receipt of an implant is disclosed. The method includes developing a preoperative plan, designing a patient specific guide based on the preoperative plan, obtaining the patient specific guide, placing the patient specific guide relative to the identified bone, fixing a pair of pins into the bone to establish an Alpha plane and executing the preoperative plan while referencing the Alpha plane. A desired amount of remaining first bone is determined based on a condition of the anatomical joint and a desired orientation of the implant. The patient specific guide includes a pair of bores defined therein and located in positions to accept a complementary pair of pins. The bores are arranged at locations on the patient specific guide to orient the respective pins in a direction optimized for surgeon access to the first bone and to establish the Alpha plane.

A method of constructing a patient-specific orthopedic implant comprising: (a) comparing a patient-specific abnormal bone model, derived from an actual anatomy of a patient's abnormal bone, with a reconstructed patient-specific bone model, also derived from the anatomy of the patient's bone, where the reconstructed patient-specific bone model reflects a normalized anatomy of the patient's bone, and where the patient-specific abnormal bone model reflects an actual anatomy of the patient's bone including at least one of a partial bone, a deformed bone, and a shattered bone, wherein the patient-specific abnormal bone model comprises at least one of a patient-specific abnormal point cloud and a patient-specific abnormal bone surface model, and wherein the reconstructed patient-specific bone model comprises at least one of a reconstructed patient-specific point cloud and a reconstructed patient-specific bone surface model; (b) optimizing one or more parameters for a patient-specific orthopedic implant to be mounted to the patient's abnormal bone using data output from comparing the patient-specific abnormal bone model to the reconstructed patient-specific bone model; and, (c) generating an electronic design file for the patient-specific orthopedic implant taking into account the one or more parameters.