Assemblies, systems, kits, and methods related to an endoprosthetic rotating hinge assembly. The exemplary embodiments disclosed herein can comprise a preassembled rotating hinge subassembly having a hingedly rotating femur box configured to be mechanically engaged to a femoral component via a femur fastening mechanism, the femur fastening mechanism being non-axially aligned with a tibial axis of rotation when the knee is in flexion or extension.

Cellulose-reinforced hydrogels may include a cellulose nanofiber network and an interstitial hydrogel portion within interstitial regions of the cellulose nanofiber network, the interstitial hydrogel portion comprising polyvinyl alcohol (PVA), wherein the hydrogel component has a crystallinity of 20% or greater.

The present invention discloses a metal-ceramic composite joint prosthesis and applications and a manufacturing method thereof. The joint prosthesis comprises a metal body and a ceramic body, wherein the metal body is integrally formed and comprises a porous structure layer, a boundary layer and a root-like layer, the boundary layer is located between the porous structure layer and the root-like layer, the root-like layer comprises a plurality of root-like filament clusters connected to the boundary layer but not in contact with one another, each root-like filament cluster comprises a main root perpendicularly connected to the boundary layer and a plurality of fibrous roots connected to the lateral side of the main root, the fibrous roots extend obliquely towards the side away from the boundary layer, and the ceramic body covers the root-like filament clusters and is formed on the boundary layer. The joint prosthesis achieves the compositing of metal and ceramic, thereby achieving both a wear-resistant ceramic body required for a joint friction surface and a porous metal structure with a good bone ingrowth effect required for an osseointegration surface. The root-like filament clusters of the root-like layer are rooted in the ceramic body, to form a tight and stable connection between the ceramic body and the metal body, and the root-like clusters being not in contact with one another prevents the ceramic body from locally breaking or cracking.

Provided herein are biomimetic osteochondral implants that are generally useful for the at least partial resurfacing of damaged cartilage within a joint. The implants are constructed to have a modular, layered structure in which the physical properties (e.g., stiffness and lubricity) or dimensions of each layer can be adjusted (e.g., by using the appropriate material and controlling the thickness thereof) based on the anatomy to be replaced. For example, the material and or thicknesses of the layers can be selected to approximate the physical properties and/or dimensions of cartilage (and, optionally, chondral and subchondral bone). Also provided herein are methods of treatment involving the use of said biomimetic osteochondral implants to repair an osteochondral defect in a joint.

An interbody device may include a main body and an arm movably connected thereto. The device may have a first end, a second end opposite the first end in a direction of a longitudinal axis of the device, a first side, a second side opposite the first side in a direction of a first transverse axis of the device, a third side, and a fourth side opposite the third side in a direction of a second transverse axis of the device. An overall distance between the first side and the second side may increase along at least a majority of a length of the device in a direction from the first end toward the second end, and an overall distance between the third side and the fourth side may increase along at least a majority of the length in a direction from the second end toward the first end.

Cellulose-reinforced hydrogels may include a cellulose nanofiber network and an interstitial hydrogel portion within interstitial regions of the cellulose nanofiber network, the interstitial hydrogel portion comprising polyvinyl alcohol (PVA), wherein the hydrogel component has a crystallinity of 20% or greater.

An intervertebral disc includes a superior endplate having an upper vertebral contacting surface and a lower bearing surface, wherein the upper vertebral contacting surface of the superior endplate has a central portion that is raised relative to a peripheral portion of the superior endplate, and wherein the lower bearing surface has a concavity disposed opposite the raised central portion. The disc includes an inferior endplate having a lower vertebral contacting surface and an upper surface, wherein the lower vertebral contacting surface of the inferior endplate has a central portion and wherein the upper bearing surface has a concavity disposed opposite the central portion. A core is positioned between the upper and inferior endplates, the core having upper and lower core bearing surfaces configured to mate with the bearing surfaces of the upper and inferior endplates. The upper vertebral contacting surface of the superior end plate has a different shape than the lower vertebral contacting surface of the inferior end plate.

A coating of blue-black or black zirconium of uniform and controlled thickness on a zirconium or zirconium alloy material is accomplished through the treatment of an amorphous zirconium or zirconium alloy substrate, which may have an altered surface roughness. The treatment of amorphous zirconium or zirconium alloy substrates includes oxidation of the substrates. A zirconium coating of uniform and controlled thickness is especially useful in various applications because the uniformly thick zirconium surface of controlled depth provide a barrier against implant corrosion caused by ionization of the metal substrates.

A liner is arranged for use in prosthetic and orthopedic devices. The liner defines first and second end portions, and inner and outer surfaces. The liner includes an inner layer having a frictional component and forms at least part of the periphery of the inner liner surface. The inner layer defines a plurality of apertures. A porous element is in communication with the inner liner surface and is connected to the inner layer such that the apertures permit a transfer of air from the inner surface to the porous element. A base layer adjoins the porous element and extends between the first and second end portions of the liner.

The present invention discloses a metal-ceramic composite joint prosthesis and applications and a manufacturing method thereof. The joint prosthesis comprises a metal body and a ceramic body, wherein the metal body is integrally formed and comprises a porous structure layer, a boundary layer and a root-like layer, the boundary layer is located between the porous structure layer and the root-like layer, the root-like layer comprises a plurality of root-like filament clusters connected to the boundary layer but not in contact with one another, each root-like filament cluster comprises a main root perpendicularly connected to the boundary layer and a plurality of fibrous roots connected to the lateral side of the main root, the fibrous roots extend obliquely towards the side away from the boundary layer, and the ceramic body covers the root-like filament clusters and is formed on the boundary layer. The joint prosthesis achieves the compositing of metal and ceramic, thereby achieving both a wear-resistant ceramic body required for a joint friction surface and a porous metal structure with a good bone ingrowth effect required for an osseointegration surface. The root-like filament clusters of the root-like layer are rooted in the ceramic body, to form a tight and stable connection between the ceramic body and the metal body, and the root-like clusters being not in contact with one another prevents the ceramic body from locally breaking or cracking.