A stem (100) for use in a joint prosthesis, such as a femoral stem for a hip joint prosthesis, the stem comprising: a solid central core (102); a proximal outer layer (127) disposed over a proximal portion (101a) of the central core, wherein the proximal outer layer comprises a set of longitudinal ribs (120), defining slots (130) there between; and a distal outer layer made of a deformable porous material disposed over a distal portion (101b) of the central core. The arrangement is such that the stem (100) can be made with a relatively large diameter yet without being excessively stiff, for cementless fixation in osteoporotic patients. The deformability of the distal outer layer also mitigates against the risk of intraoperative bone fractures.

A bone graft system includes a two-dimensional mesh sheet sized and shaped to, when folded along fold lines, form a three-dimensional graft containment structure configured to be packed with a bone graft material for placement within a target area of a bone, the mesh sheet including a first end flap connected to a remaining portion of the mesh sheet via a first fold line and a second end flap connected to the remaining portion of the mesh sheet via a second fold line, a third fold line extending from the first fold line to the second fold line so that the remaining portion is configured to be wrapped around folded first and second end flaps to form the graft containment structure, the first and second end flaps substantially corresponding to a profile of the target area of the bone.

A medical appliance or prosthesis may comprise one or more layers of electrospun nanofibers, including electrospun polymers. The electrospun material may comprise layers including layers of polytetrafluoroethylene (PTFE). Electrospun nanofiber mats of certain porosities may permit tissue ingrowth into or attachment to the prosthesis.

A medical appliance or prosthesis may comprise one or more layers of electrospun nanofibers, including electrospun polymers. The electrospun material may comprise layers including layers of polytetrafluoroethylene (PTFE). Electrospun nanofiber mats of certain porosities may permit tissue ingrowth into or attachment to the prosthesis.

Acetabular implant and method for its manufacture, wherein the implant has a bone side with a contact surface to be fixed against the bone of the hip socket. A plastically deformable zone with an open porous structure connects to the contact surface, the zone being formed by a three-dimensional structure composed of strut elements with opposite ends, wherein these strut elements are connected at their ends in nodes. The zone is made of a material having an elongation at break of at least 15%.

A medical appliance or prosthesis may comprise one or more layers of electrospun nanofibers, including electrospun polymers. The electrospun material may comprise layers including layers of polytetrafluoroethylene (PTFE). Electrospun nanofiber mats of certain porosities may permit tissue ingrowth into or attachment to the prosthesis.

A bone graft system includes a two-dimensional mesh sheet sized and shaped to, when folded along fold lines, form a three-dimensional graft containment structure configured to be packed with a bone graft material for placement within a target area of a bone, the mesh sheet including a first end flap connected to a remaining portion of the mesh sheet via a first fold line and a second end flap connected to the remaining portion of the mesh sheet via a second fold line, a third fold line extending from the first fold line to the second fold line so that the remaining portion is configured to be wrapped around folded first and second end flaps to form the graft containment structure, the first and second end flaps substantially corresponding to a profile of the target area of the bone.

An expandable intervertebral implant is disclosed for use in between adjacent vertebral bodies in a spine. An expandable intervertebral implant may include an upper plate having a first upper side and a second upper side, a lower plate having a first lower side, a second lower side, and a first lattice that connects the first upper side to the first lower side. The expandable intervertebral implant may further include a second lattice that connects the second upper side of the upper plate to the second lower side of the lower plate and an opening having a longitudinal axis between the upper plate, lower plate, first lattice, and second lattice. The expandable intervertebral implant may further include an expansion mechanism comprising a driver that expands the upper plate and the lower plate away from each other along a cephalad-caudal axis by deforming the first lattice and the second lattice.

A method of making a multi-layer osteogenic carrier device for use in a vertebral column of a patient, comprising producing an elongated tubular structure, the elongated tubular structure comprising a closed end and an open end, wherein the open end is adapted for introducing an osteoinductive, osteogenic, and/or osteoconductive substance; cutting the elongated tubular structure to a certain length; introducing the osteoinductive, osteogenic, and/or osteoconductive substance into the open end of the elongated tubular structure; and closing the open end of the elongated tubular structure to form the multi-layer osteogenic carrier device.

A spinal stabilization system for use in a vertebral column of a patient, comprising: a multi-layer osteogenic carrier device comprising: a delivery layer comprising a porous material and an osteogenic material; and a support layer in communication with the delivery layer, the support layer capable of substantially conforming to an anatomical feature in the vertebral column of the patient, wherein the support layer holds the delivery layer in proximity to the anatomical feature; at least one rod; at least one rod clip; and at least one fastener are disclosed. The multi-layer osteogenic carrier device can further comprise an adhesive layer capable of adhering the carrier to at least a portion of an anatomical feature, the adhesive layer in communication with at least a portion of the delivery layer.