The present invention relates to a three-dimensional multiphasic synthetic tissue scaffold comprising first, second and third compartments, wherein: each said compartment comprises distinct microstructural, and/or chemical, and/or mechanical properties, and is connected with at least one other compartment of the scaffold via a continuous interface; the tissue scaffold is porous; and the external morphology of the tissue scaffold mimics that of a mammalian joint or a component thereof. The invention further relates to a method for producing the three dimensional multiphasic synthetic tissue scaffold using a polymeric material, the method comprising using a three-dimensional (3D) bioprinter to print the tissue scaffold by continuously deposit the polymeric material onto a platform until the tissue scaffold is produced in its entirety.

A method for bone reconstruction includes aligning a first bone with a second bone using a plurality of guidewires to correct rotational deformity of the first and second bones. A first module of a targeting apparatus is positioned in proximity to the first bone. A tip of the first module is engaged with the first bone. A second module of the targeting apparatus is positioned in proximity to the second bone. A tip of the second module is engaged with the second bone. Alignment of the first module and the second module is secured. The alignment is verified using a guidewire, the guidewire wire is inserted through a passage extending through the second module. A length between the first bone and the second bone is determined using a depth gauge. An implant is selected based on the determined length for delivery along the passage extending through the second module.

A surgical implant for a proximal carpal row replacement surgery employs a scanned image of each of the scaphoid, lunate and triquetrum bones for generating a unitary, homogeneous model defining a fused shape for implantation as the proximal carpal row. The implant utilizes a contralateral image of healthy bones of the patient for generating the replacement model, and employs shrink-wrap and smoothing processing to generate the unitary replacement. The resulting implant replaces the intercalary bone structures of the scaphoid, lunate and triquetrum with a single appliance, and is slideably engaged with the distal carpal row via a surgical tunnel and tethered by a resectioned tendon, ligament, or other connective member. The implant facilitates wrist function since the unitary implant replaces skeletal structures that are encapsulated by adjacent bones and frequently move as a unit, while eliminating gaps, voids and ligaments between the intercalary structure.

A joint replacement device includes a male component with a structure to couple to a bone on one side of a joint, and an outer articulation surface that is attached to the structure via a neck. A female component is configured to couple to a bone on an opposite side of the joint and includes a cavity that is surrounded by an inner articulation surface. An opening of the cavity is shaped to enable insertion of the outer articulation surface into the cavity when the outer articulation surface is aligned with the opening, and to prevent separation of the male component from the female component when rotated so as not to align with the opening. The neck is located within the opening and the outer articulation surface is rotatable within the outer articulation surface with a rotation that is limited by dimensions of the opening and the neck.

A method for bone reconstruction includes aligning a first hone with a second bone using a plurality of guidewires to correct rotational deformity of the first and second bones. A first module of a targeting apparatus is positioned in proximity to the first bone. A tip of the first module is engaged with the first bone. A second module of the targeting apparatus is positioned in proximity to the second bone. A tip of the second module is engaged with the second bone. Alignment of the first module and the second module is secured. The alignment is verified using a guidewire, the guidewire wire is inserted through a passage extending through the second module. A length between the first bone and the second bone is determined using a depth gauge. An implant is selected based on the determined length for delivery along the passage extending through the second module.

The present invention relates to a three-dimensional multiphasic synthetic tissue scaffold comprising first, second and third compartments, wherein: each said compartment comprises distinct microstructural, and/or chemical, and/or mechanical properties, and is connected with at least one other compartment of the scaffold via a continuous interface; the tissue scaffold is porous; and the external morphology of the tissue scaffold mimics that of a mammalian joint or a component thereof. The invention further relates to a method for producing the three dimensional multiphasic synthetic tissue scaffold using a polymeric material, the method comprising using a three-dimensional (3D) bioprinter to print the tissue scaffold by continuously deposit the polymeric material onto a platform until the tissue scaffold is produced in its entirety.

A joint replacement device includes a male component with a structure to couple to a bone on one side of a joint, and an outer articulation surface that is attached to the structure via a neck. A female component is configured to couple to a bone on an opposite side of the joint and includes a cavity that is surrounded by an inner articulation surface. An opening of the cavity is shaped to enable insertion of the outer articulation surface into the cavity when the outer articulation surface is aligned with the opening, and to prevent separation of the male component from the female component when rotated so as not to align with the opening. The neck is located within the opening and the outer articulation surface is rotatable within the outer articulation surface with a rotation that is limited by dimensions of the opening and the neck.

A method for bone reconstruction includes aligning a first hone with a second bone using a plurality of guidewires to correct rotational deformity of the first and second bones. A first module of a targeting apparatus is positioned in proximity to the first bone. A tip of the first module is engaged with the first bone. A second module of the targeting apparatus is positioned in proximity to the second bone. A tip of the second module is engaged with the second bone. Alignment of the first module and the second module is secured. The alignment is verified using a guidewire, the guidewire wire is inserted through a passage extending through the second module. A length between the first bone and the second bone is determined using a depth gauge. An implant is selected based on the determined length for delivery along the passage extending through the second module.

A surgical implant for a proximal carpal row replacement surgery employs a scanned image of each of the scaphoid, lunate and triquetrum bones for generating a unitary, homogeneous model defining a fused shape for implantation as the proximal carpal row. The implant utilizes a contralateral image of healthy bones of the patient for generating the replacement model, and employs shrink-wrap and smoothing processing to generate the unitary replacement. The resulting implant replaces the intercalary bone structures of the scaphoid, lunate and triquetrum with a single appliance, and is slideably engaged with the distal carpal row via a surgical tunnel and tethered by a resectioned tendon, ligament, or other connective member. The implant facilitates wrist function since the unitary implant replaces skeletal structures that are encapsulated by adjacent bones and frequently move as a unit, while eliminating gaps, voids and ligaments between the intercalary structure.

A scapholunate stabilisation implant includes a central part having an elastic deformation capacity enabling the traction movements of the implant, and two end parts having an elastic deformation capacity enabling the torsional movements of the implant, the end parts being provided with at least one hole through which the fixing screw is passed, the central part and the end parts being connected by rods that can withstand the torsional deformations of the implant.