An expandable intervertebral implant is provided for insertion into an intervertebral space defined by adjacent vertebrae. The expandable intervertebral implant includes a pair of outer sleeve portions and an inner core disposed between the outer sleeve portions. Movement of the inner core relative to the outer sleeve portions causes the outers sleeve portions to deflect away from each other, thereby engaging the expandable intervertebral implant with the vertebrae and adjusting the height of the intervertebral space.

A vertebral insert may include a first linkage, a second linkage, and a third linkage. The first, second, and third linkages may at least partially defining a cavity. The insert may be movable between a collapsed configuration and an expanded configuration, and the movement of the first and second linkages with respect to one another may be configured to reciprocally move the insert between the collapsed and expanded configurations.

An expandable intervertebral implant is provided for insertion into an intervertebral space defined by adjacent vertebrae. The expandable intervertebral implant includes a pair of outer sleeve portions and an inner core disposed between the outer sleeve portions. Movement of the inner core relative to the outer sleeve portions causes the outers sleeve portions to deflect away from each other, thereby engaging the expandable intervertebral implant with the vertebrae and adjusting the height of the intervertebral space.

An expandable intervertebral implant is provided for insertion into an intervertebral space defined by adjacent vertebrae. The expandable intervertebral implant includes a pair of outer sleeve portions and an inner core disposed between the outer sleeve portions. Movement of the inner core relative to the outer sleeve portions causes the outers sleeve portions to deflect away from each other, thereby engaging the expandable intervertebral implant with the vertebrae and adjusting the height of the intervertebral space.

An implant for restoring height of a vertebral body. The implant includes upper and lower plates configured to be moved away from one another in the craniocaudal direction for the implant to be deployed. Supports are coupled to the upper plate and a distal end portion, and arranged in a crisscross configuration in the proximal-to-distal direction in each of an insertion configuration and a deployed configuration. The crisscross configuration facilitates increased expansion of the implant. The supports may be laterally spaced from one another to define a void space for receiving retaining element, and inner and outer arcuate surfaces may provide a generally cylindrical profile to the implant. One of the supports may be a support fork arranged in a V-shaped configuration. A length of the supports may be approximately 50-90% of a length of the upper and lower plates. The implant may be formed through additive manufacturing.

An expandable intervertebral implant is provided for insertion into an intervertebral space defined by adjacent vertebrae. The expandable intervertebral implant includes a pair of outer sleeve portions and an inner core disposed between the outer sleeve portions. Movement of the inner core relative to the outer sleeve portions causes the outers sleeve portions to deflect away from each other, thereby engaging the expandable intervertebral implant with the vertebrae and adjusting the height of the intervertebral space.

An implant for restoring height of a vertebral body. The implant includes upper and lower plates configured to be moved away from one another in the craniocaudal direction. A first support and a second support are arranged to crisscross in a proximal-to-distal direction to facilitate increased expansion of the implant, and a third support and a fourth support may be arranged to crisscross in the proximal-to-distal direction. Certain supports may be laterally spaced from one another to define a void space for receiving a retaining element. An upper support fork may include a first pair of supports arranged in a V-shaped configuration and converge at an apex that is coupled to an underside of the upper plate. A lower support fork may include a second pair of supports arranged in a V-shaped configuration and converge at another apex that is coupled to an upper side of the lower plate.

An interbody spinal cage when implanted can be manipulated non-invasively to change dimensions conforming to contours of adjacent vertebral bones. The interbody spinal cage includes a flexible shell that encases multiple variable-length rods. Each of the multiple variable-length rods includes telescoping tubes and an actuator for increasing and decreasing the length of the telescoping tubes. Each of the variable-length rods includes a retention member to limit movements of the telescoping tubes, wherein the retention member can be engaged and disengaged. Both the retention member and the actuator can be operated from outside the body in which the interbody spinal cage is implanted.

An expandable intervertebral implant is provided for insertion into an intervertebral space defined by adjacent vertebrae. The expandable intervertebral implant includes a pair of outer sleeve portions and an inner core disposed between the outer sleeve portions. Movement of the inner core relative to the outer sleeve portions causes the outers sleeve portions to deflect away from each other, thereby engaging the expandable intervertebral implant with the vertebrae and adjusting the height of the intervertebral space.

Enzymatic and non-enzymatic detectors and associated membrane apparatus, and methods of use, such as within a fully implantable sensor apparatus. In one embodiment, detector performance is controlled through selective use of membrane configurations and enzyme region shapes, which enable accurate detection of blood glucose level within the solid tissue of the living host for extended periods of time. Isolation between the host's tissue and the underlying enzymes and reaction byproducts used in the detectors is also advantageously maintained in one embodiment via use of a non-enzyme containing permeable membrane formed of e.g., a biocompatible crosslinked protein-based material. Control of response range and/or rate in some embodiments also permits customization of sensor elements. In one variant, heterogeneous detector elements are used to, e.g., accommodate a wider range of blood glucose concentration within the host. Methods of manufacturing the membranes and detectors, including methods to increase reliability, are also disclosed.